[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"anxiety-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:anxiety-disease":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100650258","tracking-risk-in-adolescents-and-children-for-early-identification-of-common-mental-disorders-100650258",false,"NCT07744490","Tracking Risk in Adolescents and Children for Early Identification of Common Mental Disorders","A Longitudinal Study for Risk Identification of Common Mental Disorders in High-Risk Children and Adolescents","TRACE","Inclusion Criteria:\n\n1. Aged 7-17 years at enrollment.\n2. Meeting at least one of the following conditions: Having at least one first-degree relative with a depressive disorder, anxiety disorder, or obsessive-compulsive disorder; or exhibiting clinically relevant but subthreshold depressive, anxiety, obsessive-compulsive, or repetitive behavioral symptoms.\n3. Not meeting the full diagnostic criteria for a depressive disorder, anxiety disorder, or obsessive-compulsive disorder at baseline, as assessed using the K-SADS-PL.\n4. Willing and able to participate in the scheduled assessments and follow-up visits.\n5. Written informed consent provided by a parent or legal guardian and assent provided by the participant\n\nExclusion Criteria:\n\n1. A current or previous diagnosis of a depressive disorder, anxiety disorder, or obsessive-compulsive disorder.\n2. A severe psychiatric condition requiring immediate clinical intervention, including acute suicide risk, a psychotic disorder, or a bipolar disorder.\n3. A major neurological disorder, severe head injury, or serious or unstable medical condition that may interfere with study participation.\n4. Intellectual or cognitive impairment that prevents the participant from understanding or completing the study assessments.\n5. Inability or unwillingness of the participant or legal guardian to comply with the study procedures.","ALL","7 Years","17 Years",{"count":21,"type":22},200,"ESTIMATED","2 Years","OBSERVATIONAL","This prospective observational cohort study will enroll approximately 200 children and adolescents aged 7-17 years who are at elevated risk for common mental disorders, including depressive disorders, anxiety disorders, and obsessive-compulsive disorder, based on family history or subthreshold emotional or behavioral symptoms. Participants will be followed for two years. Clinical assessments, questionnaires, EEG, biological samples, and MRI will be collected at scheduled intervals. The study aims to identify factors associated with the onset and progression of these disorders and support early risk identification.",[27,28,29,30],"High Risk","Depression \u002F Major Depressive Disorder","Anxiety Disease","Obsessive - Compulsive Disorder",[32,33,34,35],"children and adolescence","pediatric","high risk","mental disease","NOT_YET_RECRUITING","2026-07-30",{"date":39,"type":40},"2026-08-04","ACTUAL",{"date":42,"type":22},"2026-07-25",{"date":44,"type":22},"2030-12-31",{"name":46,"class":47},"Shanghai Mental Health Center","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":69,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":48},"100619960","vr-counseling-to-reduce-public-speaking-anxiety-100619960","NCT07351409","VR-Counseling to Reduce Public Speaking Anxiety","Immersive Virtual Reality as a Tool for Reducing Public Speaking Anxiety in Students Accessing the University Psychological Counseling Service: A Randomized Controlled Trial","VR-Counseling","Inclusion criteria are:\n\n1. current enrollment at the university;\n2. request for psychological counseling at the UPCS;\n3. fluency in Italian;\n4. provision of written informed consent;\n5. the presence of at least moderate levels of anxiety and perceived stress, as indicated by scores on standardized assessment instruments. Specifically, scores between STAI scores from 35 to 50 and PRPSA scores from 85 to 110.\n\nExclusion criteria are:\n\n1. current psychotic disorder;\n2. acute suicidality;\n3. severe substance dependence;\n4. severe sensory or motor impairments that would prevent safe use of VR equipment;\n5. inability to attend the planned sessions;\n6. concurrent participation in other specialized psychotherapy programs.","18 Years","40 Years",{"count":60,"type":22},72,"INTERVENTIONAL",[63],"NA","Public Speaking Anxiety (PSA) is a common manifestation of social anxiety among university students that can negatively impact academic performance and psychological well-being. Virtual Reality (VR) based interventions combined with Cognitive Behavioral Therapy (CBT) represent a promising approach to address PSA by enabling controlled, gradual exposure to feared social situations through realistic simulations of audiences and settings. This randomized controlled trial will evaluate whether integrating VR sessions into standard psychological counseling provided by the University Psychological Counseling Service (UPCS) improves anxiety and PSA outcomes in university students compared with counseling alone.\n\nParticipants will be randomized to one of two groups: (1) a control group receiving standard psychological counseling intervention, or (2) an experimental group receiving psychological counseling supplemented with VR interventions delivered via immersive 360° video scenarios. The VR-based intervention includes a VR-Exposure and Response Prevention (ERP) module offering graded exposure to anxiety-provoking public speaking contexts, and a VR-Acceptance and Commitment Training (ACT) module aimed at enhancing mindfulness and psychological flexibility through guided experiential exercises. Psychological outcomes and physiological responses recorded during sessions will be analyzed to compare the effectiveness of VR-integrated counseling versus standard counseling alone. This study addresses the limited evidence on CBT combined with 360° video-based VR exposure for PSA in university students and introduces a novel VR-based ERP and ACT protocol tailored to a university counseling setting.",[66,67,29,68],"Anxiety and Distress","Anxiety","Public Speaking Anxiety",[70,71,72],"Public speaking anxiety","university counseling","Virtual Reality","2026-01-09",{"date":75,"type":40},"2026-01-20",{"date":77,"type":22},"2026-03-01",{"date":79,"type":22},"2026-12-31",{"name":81,"class":47},"University of Calabria"]