[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"attention-deficit-hyperactivity-disorder-in-adults\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:attention-deficit-hyperactivity-disorder-in-adults":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100652556","the-effect-of-5-hydroxytryptophan-on-adhd-traits-and-eye-movements-100652556",false,"NCT07777328","The Effect of 5-hydroxytryptophan on ADHD Traits and Eye Movements","The Effect of 5-hydroxytryptophan on Microsaccades and Distractibility in Individual With High Levels of ADHD Traits: a Randomised, Double-blind Trial","Inclusion Criteria:\n\n* 18-65 years of age\n* Normal or corrected to normal vision with contact lenses.\n* Score of \\\u003C9 or \\>14 on the ASRS v5 (assessed in pre screen questionnaire)\n\nExclusion Criteria:\n\n* Current use of psychostimulant medication or medication for the treatment of ADHD\n* Current use of medications known to impact the serotonergic system (e.g., SSRIs).\n* Smoking or vaping\n* Pregnancy\n* Breast feeding\n* Lactose intolerance\n* Veganism\n* Dyslexia",true,"ALL","18 Years","65 Years",{"count":21,"type":22},150,"ESTIMATED","INTERVENTIONAL",[25],"NA","The aim of this project is to look at the impact of 5-Hydroxytryptophan (5-HTP) on distractibility. 5-HTP is the precursor to the neurotransmitter serotonin and is a chemical that the body produces naturally. There is evidence that distractibility is associated with a decreased level of serotonin. This research aims to see if giving people 5-HTP will alter their distractibility, which will form part of an initial assessment as to whether 5-HTP could be used to support people with attention problems. The study involves completing a short survey about mental health and behaviours, and if eligible, participation in an in-person study at the University of Sheffield. The in-person session involves completing some cognitive tasks to look at eye movement, taking 5-HTP or a sugar tablet with no active ingredients, and then completing the tasks again after a 90-minute wait.",[28,29,30],"Attention Deficit and Hyperactivity Disorder (ADHD)","Attention Deficit Hyperactivity Disorder in Adults","Attention Deficits",[32,33,34,35,36,37],"5-Hydroxytryptophan","Serotonin","ADHD","microsaccades","eye tracking","attention","RECRUITING","2026-08-18",{"date":41,"type":42},"2026-08-20","ACTUAL",{"date":44,"type":42},"2025-11-25",{"date":46,"type":22},"2027-06",{"name":48,"class":49},"University of Sheffield","OTHER"]