[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"autologous-breast-reconstruction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:autologous-breast-reconstruction":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100649035","long-term-evaluation-of-quality-of-life-and-aesthetic-outcomes-after-autologous-breast-reconstruction-using-the-profunda-artery-perforator-pap-flap-100649035",false,"NCT07728565","Long-term Evaluation of Quality of Life and Aesthetic Outcomes After Autologous Breast Reconstruction Using the Profunda Artery Perforator (PAP) Flap","QUALIPAP","Inclusion Criteria:\n\n* Female patients aged 18 years or older.\n* History of unilateral or bilateral breast reconstruction using a profunda artery perforator (PAP) flap.\n* Breast reconstruction performed between 2014 and 2024 at the European Georges Pompidou Hospital.\n* Able to understand study procedures and complete study questionnaires.\n* Provided non-opposition\u002Fconsent to participate according to French regulations.\n\nExclusion Criteria:\n\n* Patients younger than 18 years.\n* Breast reconstruction performed using techniques other than PAP flap.\n* Breast reconstruction performed outside the study period (2014-2024).\n* Patients under legal protection measures.\n* Severe cognitive impairment or major psychiatric disorder preventing questionnaire completion.\n* Hearing impairment preventing participation in the interview process.\n* Insufficient French language proficiency.\n* Missing essential clinical data.\n* Explicit refusal to participate.","FEMALE","18 Years",{"count":19,"type":20},264,"ESTIMATED","1 Day","OBSERVATIONAL","Breast reconstruction using autologous tissue is an important option for women undergoing mastectomy for breast cancer. The profunda artery perforator (PAP) flap is a reliable alternative when abdominal tissue is unavailable or unsuitable for reconstruction. Although the PAP flap is increasingly used, limited data are available regarding long-term patient-reported quality of life, aesthetic outcomes, and donor-site morbidity.\n\nThis monocentric observational study aims to evaluate long-term quality of life in women who underwent breast reconstruction with a PAP flap at the European Georges Pompidou Hospital between 2014 and 2024. Participants will complete validated patient-reported outcome questionnaires (BREAST-Q Reconstruction Module and PROMIS-29) and undergo a standardized clinical and photographic assessment. Aesthetic outcomes will be evaluated using objective photographic analysis and blinded expert review.\n\nThe study will provide comprehensive information on patient satisfaction, functional outcomes, aesthetic results, and donor-site sequelae following PAP flap breast reconstruction.",[25,26,27],"Breast Cancer","Acquired Absence of Breast","Autologous Breast Reconstruction",[29,30,31,27,32,33,34,35,36,37],"PAP Flap","Profunda Artery Perforator Flap","Breast Reconstruction","Quality of Life","BREAST-Q","PROMIS-29","Aesthetic Outcome","Donor Site Morbidity","Mastectomy","NOT_YET_RECRUITING","2026-07-30",{"date":41,"type":42},"2026-08-03","ACTUAL",{"date":44,"type":20},"2026-08-01",{"date":46,"type":20},"2028-08-31",{"name":48,"class":49},"Assistance Publique - Hôpitaux de Paris","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":17,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":4},"100562338","phase-4-the-impact-of-nutritional-optimization-to-enhance-postoperative-outcomes-using-the-r-support-supplements-100562338","NCT06601868","The Impact of Nutritional Optimization to Enhance Postoperative Outcomes Using the R-Support Supplements","R-Support","Inclusion Criteria:\n\n* ASAI\\&II\n* Age 18-65\n* Type of surgery:\n\n  * Abdominoplasty o Breast reduction\n  * Breast reconstruction through a DIEaP-flap\n  * Extensive circumferential liposuction and body contouring surgery\n\nExclusion Criteria:\n\n* Patients with systemic illness, including:\n\n  * Diabetes\n  * Immune deficiencies\n  * Severe cardiovascular disease\n  * Renal insufficiency\n* Active smokers or smokers that didn't quit 4 weeks prior to surgery\n* Patients under chemotherapy (Patients currently undergoing chemotherapy are not allowed to participate in this study. Patient undergoing previous chemotherapy are allowed to participate in this study, as long as the chemotherapy ended 6 months before the planned surgery and are currently in remission or free of disease.)\n* Patients after bariatric surgery with partial or complete stomachresection\n* Patients taking SSRI medication\n* Pregnancy\n* ASAIII\\&IV\n* Gluten intolerance\n* Lactose intolerance\n* Allergy or hypersensitivity to fish, soya, milk, shellfish.",true,"ALL","65 Years",{"count":62,"type":20},200,"INTERVENTIONAL",[65],"PHASE4","The aim of this pilot study is to evaluate the potential benefits of nutrient supplementation on post-operative recovery for patients undergoing certain types of surgery, compared to those who do not receive such supplementation. The multi-center study will be conducted in Belgium and the Netherlands at UZ Brussel, Delta CHIREC, and Zuyderland Medical Center.\n\nThe pilot study will serve as a precursor to a randomized controlled trial and will include 200 patients. Participants must be classified as ASA I or II, aged between 18 and 65, and undergoing abdominoplasty, breast reduction, breast reconstruction through a DIEP-flap, or extensive circumferential liposuction and body contouring surgery.\n\nEligible patients who provide informed consent will be randomly assigned to either the intervention group, receiving R-Support supplementation, or the control group, without supplementation. Each group will consist of 100 patients. The study will span 8 weeks, with a 2-week preoperative period and a 6-week postoperative period. The treatment will involve a 28-day supplementation period, with R-Support Recover Prepare given 14 days preoperatively and R-Support Recover After given 14 days postoperatively.\n\nPostoperative recovery will be assessed using the PRP-Questionnaire and Functional Recovery Index, which together will measure physical and psychological recovery, as well as the speed of recovery in the early postoperative phase. The study hypothesizes that the intervention group will experience quicker recovery than the control group. Additionally, data on hospital stay duration and early postoperative complications will be collected, with the expectation that better-prepared bodies will recover faster, potentially leading to fewer hospitalized days and complications. The study aims to demonstrate enhanced postoperative recovery, reduced early complications (such as wound dehiscence and infection), and shorter hospital stays.",[68,69,27,70],"Abdominoplasty","Breast Reduction","Body Contouring Surgery","2024-09-18",{"date":73,"type":42},"2024-09-20",{"date":75,"type":20},"2024-10-01",{"date":77,"type":20},"2025-12-31",{"name":79,"class":49},"Universitair Ziekenhuis Brussel"]