[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"avoidantrestrictive-food-intake-disorder-arfid\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:avoidantrestrictive-food-intake-disorder-arfid":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100642283","cognitive-behavioral-therapy-vs-nutrition-counseling-for-avoidantrestrictive-food-intake-disorder-part-ii-100642283",false,"NCT07641205","Cognitive-behavioral Therapy vs. Nutrition Counseling for Avoidant\u002FRestrictive Food Intake Disorder Part II","Cognitive and Neural Mechanisms of Cognitive-Behavioral Therapy for Avoidant\u002FRestrictive Food Intake Disorder Part II: Mediation Effects","COUNTERACT-2","Inclusion Criteria:\n\n* Males and Females ages 10-18 years old\n* Current ARFID assessed via Feeding and Eating Disorders Model from the \"Enhanced\" Structured Interview for DSM-5 (SCID-5)\n* Normal TSH or free T4 levels to rule out thyroid disease as cause of symptoms inclusionary for randomization\n* Negative celiac screening panel indicating no active celiac disease as cause of symptoms inclusionary for randomization\n* Fluency and literacy in English\n\nExclusion Criteria:\n\n* Patient requires weight restoration treatment (e.g., \\\u003C 5th percentile of BMI, height, or weight for sex and age; patient has fallen off individual growth trajectory; patient's medical providers have recommended weight restoration) such that 15 sessions of CBT-AR is not appropriate\n* Pregnancy, breastfeeding, or recent initiation\u002Fcessation of estrogen-containing systemic contraceptives within 8 weeks of the pre-treatment study visit (as these could impact neuroimaging)\n* Current\u002Fhistory of psychosis via Mini-International Neuropsychiatric Interview child\u002Fadolescent version (MINI KID)\n* Substance\u002Falcohol use disorder (active within the past month) via MINI KID\n* Medical instability requiring inpatient care according to the American Psychiatric Association 2006 treatment guidelines for eating disorders\n* Laboratory abnormalities indicating a need for higher level of care (assessed by complete blood count and comprehensive metabolic panel) exclusionary for randomization\n* Complete lack of oral intake (suggesting a need for inpatient care)\n* Tube feeding (suggesting a need for tube weaning) Significant weight\u002Fshape concern-motivating eating pathology as evidenced by a global Eating Disorders Examination Questionnaire (EDE-Q) score greater than 4\n* Active suicidal ideation with intent or plan via the 5-item Self-Injurious Thoughts and Behaviors Interview-Revised (SITBI-R)\n* Contraindications to MRI\n* History of major gastrointestinal tract surgery or serious medical condition (e.g., cancer)\n* Medical history of intellectual disability\n* Illiteracy","ALL","10 Years","18 Years",{"count":21,"type":22},70,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study is a randomized controlled trial assessing the efficacy of cognitive- behavioral therapy (CBT-AR) and nutrition counseling for avoidant\u002Frestrictive food intake disorder (ARFID) for children and adolescents (ages 10-18 years).",[28],"Avoidant\u002FRestrictive Food Intake Disorder (ARFID)","NOT_YET_RECRUITING","2026-10-05",{"date":32,"type":33},"2026-10-07","ACTUAL",{"date":35,"type":22},"2027-11",{"date":37,"type":22},"2029-10",{"name":39,"class":40},"Massachusetts General Hospital","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":23,"phases":51,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":54,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":41},"100585116","development-and-testing-of-a-mobile-app-to-scale-delivery-of-cognitive-behavioral-therapy-for-avoidantrestrictive-food-intake-disorder-100585116","NCT06898177","Development and Testing of a Mobile App to Scale Delivery of Cognitive-behavioral Therapy for Avoidant\u002FRestrictive Food Intake Disorder","Inclusion Criteria:\n\n1. Current avoidant\u002Frestrictive food intake disorder based on DSM-5 criteria\n2. Must not have completed face-to-face CBT-AR at the Eating Disorders Clinical and Research Program at Massachusetts General Hospital\n3. Ability to speak, write, and understand English\n4. Residence in the United States\n5. Access to an internet-connected smartphone device\n\nExclusion Criteria:\n\n1. Underweight status (i.e., BMI \\\u003C 18.5 kg\u002Fm2)\n2. Complete lack of oral intake or dependence on supplemental feeding\n3. Feeding or eating disorder other than ARFID\n4. Any comorbid clinically significant disorder that would require attention beyond the study treatment\n\n6\\. Medical instability requiring inpatient care according to the American Psychiatric Association 2023 treatment guidelines for eating disorders 7. Medical history of intellectual disability 8. Illiteracy","55 Years",{"count":50,"type":22},60,[25],"Avoidant\u002Frestrictive food intake disorder (ARFID) is a serious and impairing eating disorder - occurring in up to 4% of adults - for which most individuals do not have access to treatment. The proposed study aims to develop and test a mobile app to scale delivery of cognitive-behavioral therapy for ARFID. Knowledge gained will contribute to the development of a clinically accessible, scalable, inexpensive treatment for ARFID, a highly impairing disorder for which there are significant barriers to care access.",[28],"RECRUITING","2026-06-15",{"date":57,"type":33},"2026-06-16",{"date":59,"type":33},"2026-04-13",{"date":61,"type":22},"2030-04-01",{"name":39,"class":40}]