[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"axillary-web-syndrome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:axillary-web-syndrome":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,53,79],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100652772","axillary-web-syndrome-after-breast-cancer-surgery-incidence-risk-factors-and-functional-outcomes-100652772",false,"NCT07780240","Axillary Web Syndrome After Breast Cancer Surgery: Incidence, Risk Factors, and Functional Outcomes","A Prospective Multicenter Cohort Study on the Incidence, Risk Factors, and Postoperative Functional Outcomes of Axillary Web Syndrome After Breast Cancer Surgery","Inclusion Criteria:\n\n* Age 18 years or older\n* Diagnosis of breast cancer with planned surgical treatment\n* Axillary staging performed by sentinel lymph node biopsy or axillary lymph node dissection\n* Written informed consent provided\n\nExclusion Criteria:\n\n* Preoperative restriction of shoulder range of motion\n* History of neuromuscular disease affecting the upper extremity\n* Metastatic disease\n* Anticipated inability to comply with the follow-up protocol","FEMALE","18 Years","80 Years",{"count":20,"type":21},250,"ESTIMATED","6 Months","OBSERVATIONAL","Axillary web syndrome (AWS), sometimes called \"cording,\" is a condition that can develop after breast cancer surgery in which the lymph nodes under the arm are removed or sampled. It appears as one or more tight, painful cord-like structures running from the armpit down the inner arm. It can limit shoulder movement, cause pain, and interfere with daily activities.\n\nIt is not yet clear how often AWS occurs, when it typically appears after surgery, which patients are most likely to develop it, or whether it is related to the arm swelling (lymphedema) that some patients experience after breast cancer treatment. Most previous studies looked back at patient records rather than following patients forward in time, so the answers remain uncertain.\n\nIn this study, women who are having breast cancer surgery with either sentinel lymph node biopsy or axillary lymph node dissection will be examined before their operation and then at set times afterward: 2, 4, and 8 weeks, and 3 and 6 months. At each visit, the study doctor will examine the armpit and arm for cords, measure how far the shoulder can move, ask the patient to rate any pain, and measure the circumference of both arms to check for swelling.\n\nThe study does not change the surgery or treatment a patient receives. It adds only these examinations and measurements, which are not painful and do not require blood tests or imaging. The researchers hope the results will help identify which patients are at higher risk, so that rehabilitation can be started earlier.",[26,27,28,29],"Axillary Web Syndrome","Breast Cancer","Breast Cancer Lymphedema","Postoperative Complications",[31,32,33,34,35,36,37,38,39],"axillary web syndrome","cording","lymphatic cording","sentinel lymph node biopsy","axillary lymph node dissection","shoulder range of motion","breast cancer surgery","postoperative morbidity","prospective cohort","RECRUITING","2026-08-19",{"date":43,"type":44},"2026-08-21","ACTUAL",{"date":46,"type":44},"2026-05-01",{"date":48,"type":21},"2027-10",{"name":50,"class":51},"Antalya City Hospital","OTHER",2,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":60,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":78},"100611136","deep-learning-for-musculoskeletal-complications-in-breast-cancer-100611136","NCT07236658","Deep Learning for Musculoskeletal Complications in Breast Cancer","AI-Powered Deep Learning Models for Prospective Prediction of Musculoskeletal Complications After Breast Cancer Surgery: Focus on Lymphedema, Axillary Web Syndrome, Neuropathy, and Pain","Inclusion Criteria:\n\nFemale sex Age ≥18 years Scheduled for surgery due to unilateral breast cancer\n\nExclusion Criteria:\n\nInability to comply with follow-up visits Bilateral breast cancer Male breast cancer Children (\\\u003C18 years) Pregnant women Postpartum women Breastfeeding women Individuals in intensive care Impaired consciousness Legally incapacitated individuals",{"count":61,"type":21},133,"Survival after breast cancer has increased due to early diagnosis and advances in treatment methods. Musculoskeletal problems related to cancer and its treatment constitute a significant part of the daily practice of physiatrists and rehabilitation specialists involved in oncological rehabilitation.\n\nLymphedema can occur at any stage of a patient's life following breast cancer. Patients with breast cancer-related lymphedema require lifelong treatment, and as the stage of lymphedema progresses, response to therapy decreases. Advanced stages of lymphedema negatively affect functional status, and patients experience difficulties in performing activities of daily living.\n\nAxillary web syndrome (AWS) is characterized by a taut cord extending from the axilla to the volar surface of the wrist, typically appearing within the first 8 weeks postoperatively. AWS can complicate the administration of radiotherapy. Shoulder dysfunction may occur independently or in association with AWS. In particular, scapular dyskinesis developing after mastectomy can lead to secondary shoulder conditions such as rotator cuff syndrome or adhesive capsulitis, which are commonly observed in these patients.\n\nPeripheral neuropathy is frequently seen in patients receiving chemotherapy, adversely affecting daily life and sometimes preventing continuation of treatment. Other complications related to chemotherapy and radiotherapy include cardiotoxicity, pulmonary toxicity, fatigue, osteoporosis, and cognitive impairment.\n\nThere are also specific painful syndromes that may occur after breast cancer, including post-mastectomy pain syndrome, phantom breast pain, and musculoskeletal symptoms associated with aromatase inhibitors. All these conditions can significantly impair daily functioning and even hinder continuation of cancer treatment. Therefore, predicting these complications and implementing or developing preventive interventions is crucial.\n\nIf it is possible to predict the early development of lymphedema, axillary web syndrome, peripheral neuropathy, and painful syndromes after breast cancer, early intervention may prevent progression. This study is designed to develop and validate a predictive model using deep learning methods to determine the risk of these complications in patients undergoing breast cancer surgery. Among deep learning architectures, ResNet50, AlexNet, GoogleNet, and UNet, which have been widely used in recent studies, are planned to be implemented.\n\nAdditionally, based on the results of this study, a risk calculation program will be developed, allowing clinicians to input baseline patient data and calculate the individual patient's risk for each complication prior to treatment. No specific risk is expected in the study.",[64,65,66,67,26],"Postmastectomy Lymphedema Syndrome","Breast Cancer Surgery Pain","Osteoporosis Secondary","Shoulder Adhesive Capsulitis","2026-03-30",{"date":70,"type":44},"2026-03-31",{"date":72,"type":44},"2025-07-01",{"date":74,"type":21},"2027-01-01",{"name":76,"class":77},"Ankara Etlik City Hospital","OTHER_GOV",1,{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":16,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":4,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":97,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":4},"100613440","effects-of-muscle-energy-techniques-with-and-without-manual-axial-distraction-in-post-mastectomy-patients-with-axillary-web-syndrome-100613440","NCT07266623","Effects of Muscle Energy Techniques With and Without Manual Axial Distraction in Post-Mastectomy Patients With Axillary Web Syndrome","Effects of Muscle Energy Techniques With and Without Manual Axial Distraction on Pain, Range of Motion Anf Functional Outcomes in Post-Mastectomy Patients With Axillary Web Syndrome","MET MAD PM AWS","Inclusion Criteria:\n\n* Patients diagnosed with AWS following breast cancer surgery\n* Females aged 30 to 60 years old\n* Participants must be within 1 month to 2 years post-surgery\n* Participants having limited shoulder ROM\n* Participants must have completed their post-surgery radiation therapy and chemotherapy minimum of 2-3 weeks\n\nExclusion Criteria:\n\n* Any previous history of shoulder pathology\n* Patients with a cervical problem that radiates pain down the shoulder\n* Pregnant females\n* Bilateral mastectomy\n* Ongoing cancer stage\n* Participants with ongoing chemotherapy\n* Frozen shoulder","30 Years","60 Years",{"count":90,"type":21},58,"INTERVENTIONAL",[93],"NA","This randomized controlled trial aims to evaluate the effects of muscle energy techniques with and without manual axial distraction among post-mastectomy patients with axillary web syndrome. Fifty-eight participants will be randomly allocated into two groups and will receive the interventions for six weeks. It is hypothesized that the group that will receive both the muscle energy technique and manual axial distraction will produce greater improvements compared to the other group that will receive only MET.",[26,96],"Post-mastectomy",[98,99,100,101,102],"Axillary web syndrome","Muscle energy techniques","Manual axial distraction","Functional outcomes","Range of motion","NOT_YET_RECRUITING","2025-12-15",{"date":106,"type":44},"2025-12-22",{"date":108,"type":21},"2025-12-13",{"date":110,"type":21},"2026-05-30",{"name":112,"class":51},"Lahore University of Biological and Applied Sciences"]