[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bacterial-colonization\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bacterial-colonization":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,40,63],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100651320","risk-factors-and-clinical-implications-of-double-j-ureteral-stent-bacterial-colonization-100651320",false,"NCT07760792","Risk Factors and Clinical Implications of Double-J Ureteral Stent Bacterial Colonization","Risk Factors and Clinical Implications of Double-J Ureteral Stent Bacterial Colonization: A Prospective Cohort Study","Inclusion Criteria:\n\n* Age 18 years or older.\n* Temporary Double-J stent insertion.\n* Standard urological indication.\n* Planned stent removal during follow-up.\n* Ability to attend follow-up and provide specimens.\n* Written informed consent.\n\nExclusion Criteria:\n\n* Active urosepsis at insertion.\n* Permanent or intended long-term stenting.\n* Concomitant nephrostomy tube or urinary diversion.\n* Severe immunosuppression or neutropenia.\n* Incomplete baseline data.\n* Loss to follow-up or failure to retrieve the stent.\n* Refusal to participate.","ALL","18 Years",{"count":19,"type":20},300,"ESTIMATED","48 Weeks","OBSERVATIONAL","This prospective cohort study will evaluate the risk factors associated with bacterial colonization of Double-J ureteral stents and examine its clinical implications. Adult patients undergoing temporary ureteral stent insertion for routine urological indications will be followed until stent removal, when urine and stent cultures will be obtained. The study will assess the association between colonization and factors such as indwelling time, diabetes mellitus, chronic kidney disease, prior urinary tract infection, prior antibiotic exposure, and stent-related symptoms.",[25,26],"Bacterial Colonization","Double-J Ureteral Stents","RECRUITING","2026-08-16",{"date":30,"type":31},"2026-08-18","ACTUAL",{"date":33,"type":31},"2026-08-10",{"date":35,"type":20},"2027-07-30",{"name":37,"class":38},"Al-Azhar University","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":14,"officialTitle":14,"acronym":4,"eligibilityCriteria":44,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":45,"targetDuration":47,"studyType":22,"phases":4,"briefSummary":48,"conditions":49,"keywords":51,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":39},"100650048","risk-factors-and-clinical-implications-of-double-j-ureteral-stent-bacterial-colonization-a-prospective-cohort-study-100650048","NCT07740811","Inclusion Criteria:\n\n* Patients undergoing temporary Double-J ureteral stent insertion.\n* Stent inserted for a standard urological indication, including ureteric stone disease, ureteral obstruction, postoperative drainage, or ureteral injury repair.\n* Planned stent removal during the study follow-up period.\n* Availability for clinical follow-up and specimen collection at insertion and removal.\n* Provision of written informed consent.\n\nExclusion Criteria:\n\n* Active urosepsis at the time of stent insertion.\n* Permanent or intended long-term stenting outside the study framework.\n* Concomitant nephrostomy tube or urinary diversion that may confound microbiological results.\n* Known severe immunosuppression or neutropenia if expected to substantially alter colonization risk.\n* Patients with incomplete baseline clinical data.\n* Patients lost to follow-up or whose stent could not be retrieved for microbiological analysis.\n* Refusal to participate.",{"count":46,"type":20},400,"2 Weeks","To identify the risk factors associated with bacterial colonization of Double-J ureteral stents and to evaluate its clinical implications, including bacteriuria, UTI, antimicrobial resistance, and stent-related symptoms.",[50,25],"UTI",[50,52,53,54],"Bacterial colonization","JJ stent","infection","2026-07-28",{"date":57,"type":31},"2026-08-03",{"date":59,"type":31},"2026-04-01",{"date":61,"type":20},"2028-05-01",{"name":37,"class":38},{"id":64,"slug":65,"hasResults":11,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":71,"targetDuration":4,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":81,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":39},"100648300","enteral-nutrition-and-colonization-resistance-through-microbiota-modulation-in-critically-ill-patients-100648300","NCT07719673","Enteral Nutrition and Colonization Resistance Through Microbiota Modulation in Critically Ill Patients","Enteral Nutrition to Enhance Colonization Resistance Through Gut Microbiota Modulation in Critically Ill Patients: A Randomized Controlled Pilot Trial","MICRON","Inclusion Criteria:\n\n* Patients with medical (non-surgical) conditions admitted to the ICU.\n* ICU admission within the previous 48 hours at the study site.\n* Initiation of enteral nutrition within the first 48 hours after ICU admission.\n* Written informed consent obtained for participation in the study.\n\nExclusion Criteria:\n\n* Surgical ICU patients.\n* Patients in whom enteral nutrition was not initiated within the first 48 hours after - ICU admission.\n* Patients with galactosemia.\n* Patients with major contraindications to enteral nutrition, including: intestinal obstruction, intestinal ischemia, intestinal perforation, severe hemodynamic instability, patients who refuse participation in the study.",{"count":72,"type":20},60,"INTERVENTIONAL",[75],"NA","The goal of this clinical trial is to learn whether enteral nutrition enriched with fiber can influence gut microbiota and improve resistance to colonization with multidrug-resistant bacteria in critically ill patients. The study will also evaluate the safety and clinical outcomes associated with fiber-enriched enteral nutrition.\n\nThe main questions it aims to answer are:\n\n* Does fiber-enriched enteral nutrition reduce the acquisition of colonization with multidrug-resistant bacteria during intensive care unit (ICU) hospitalization?\n* Does fiber-enriched enteral nutrition modify the composition and diversity of the intestinal microbiota?\n* Are there differences in clinical outcomes, including adverse events, between patients receiving fiber-enriched and non-fiber enteral nutrition?\n\nResearchers will compare patients receiving fiber-enriched enteral nutrition with patients receiving standard enteral nutrition without added fiber to determine whether fiber supplementation influences gut microbiota and colonization resistance.\n\nParticipants will:\n\n* Receive enteral nutrition through a feeding tube according to their clinical needs.\n* Receive either a fiber-enriched enteral nutrition formula or a standard enteral nutrition formula.\n* Have stool samples collected during ICU hospitalization for analysis of intestinal microbiota and detection of multidrug-resistant bacteria.\n* Be monitored for clinical outcomes, infections, antibiotic exposure, and adverse events during their ICU stay and follow-up period.",[25,78,79,80],"Multidrug Resistant Organisms","Critical Illness","Gut Microbiota Dysbiosis",[82,83,84,85,86],"enteral nutrition","bacterial colonization","multidrug resistant organisms","gut microbiota","critical care","NOT_YET_RECRUITING","2026-07-20",{"date":90,"type":31},"2026-07-22",{"date":92,"type":20},"2026-10",{"date":94,"type":20},"2027-12",{"name":96,"class":38},"Iuliu Hatieganu University of Medicine and Pharmacy"]