[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"biliary-atresia-kasai-portoenterostomy-status\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:biliary-atresia-kasai-portoenterostomy-status":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100647369","eras-in-choledochal-cyst--biliary-atresia-100647369",false,"NCT07709702","ERAS in Choledochal Cyst & Biliary Atresia","Early Oral Feeding Versus Conventional Feeding After Surgery for Biliary Atresia and Choledochal Cyst: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. All children diagnosed with choledochal cyst type I and IV on MRCP or CT scan, undergoing elective Roux-En-Y hepaticojejunostomy\n2. All children with provisional diagnosis of biliary atresia undergoing Roux-En-Y portoenterostomy\n\nExclusion Criteria:\n\n1. Patients with suspected biliary atresia not undergoing portoenterostomy after Per-op cholangiogram either due to ruling out of disease or advanced disease deemed candidates for liver transplant\n2. patients with history of Emergency surgery or external drainage of choledochal cyst\n3. Hemodynamically unstable patients after surgery\n4. Previous history of GI surgery","ALL","1 Month","14 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to compare two feeding approaches after surgery for biliary atresia and choledochal cyst in children.\n\nTraditionally, children are kept without oral feeding for more than 48 hours after these operations until bowel activity returns. However, newer Enhanced Recovery After Surgery (ERAS) programs suggest that starting feeding earlier may help children recover faster.\n\nIn this study, children undergoing surgery for biliary atresia or choledochal cyst will be randomly assigned to one of two groups. One group will start oral liquids within 24 hours after surgery and gradually progress to normal feeding as tolerated (early feeding group). The other group will receive conventional care, where feeding is started after more than 48 hours once bowel activity has returned.\n\nResearchers will compare both groups for postoperative complications such as wound infection and anastomotic leakage, as well as the duration of hospital stay. Additional observations will include vomiting, abdominal distension, need for reinsertion of a nasogastric tube, requirement for repeat surgery, and time taken to resume normal feeding.\n\nParticipation in the study will not affect the standard surgical treatment provided. All children will receive routine perioperative care and will be monitored closely throughout their hospital stay and follow-up visits. The findings of this study may help determine whether early oral feeding is a safe and effective strategy to improve recovery and reduce hospitalization after pediatric hepatobiliary surgery.",[27,28],"Choledochal Cyst Resection","Biliary Atresia, Kasai Portoenterostomy Status",[30,31,32,33,34,35,36,37,38],"ERAS","Choledochal Cyst","Pediatric","Children","Post-Operative Management","Biliary Atresia","Feeding Protocol","Fast-Tract Discharge","Hospital Stay","RECRUITING","2026-07-13",{"date":42,"type":43},"2026-07-16","ACTUAL",{"date":45,"type":43},"2024-07-27",{"date":47,"type":21},"2026-08",{"name":49,"class":50},"Muhammad Zubair Shoukat","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":60,"enrollmentInfo":61,"targetDuration":63,"studyType":64,"phases":4,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":51},"100602910","cholangitis-definition-and-treatment-after-kasai-hepatoportoenterostomy-for-biliary-atresia-track-ba-study-tracking-cholangitis-post-kasai-in-biliary-atresia-100602910","NCT07129655","Cholangitis Definition and Treatment After Kasai Hepatoportoenterostomy for Biliary Atresia: TRACK-BA Study (TRacking Cholangitis Post Kasai in Biliary Atresia)","Cholangitis Definition and Treatment After Kasai Hepatoportoenterostomy for Biliary Atresia: a Feasibility Study","TRACK-BA","Inclusion Criteria:\n\n* patients with a suspected diagnosis cholangitis within 1 year after Kasai hepatoportoenterostomy\n\nExclusion Criteria:\n\n* recurrent cholangitis, cholangitis \\>1 year after Kasai","2 Years",{"count":62,"type":21},40,"1 Year","OBSERVATIONAL","Biliary atresia is a rare liver disease affecting newborns. In those babies bile ducts are blocked, and bile cannot flow from the liver to the intestines. Biliary atresia patients require a special surgery called \"Kasai operation\" to restore the bile flow. A common and serious problem after surgery is an infection of the bile ducts, called cholangitis, which can damage the liver and lead an earlier need for liver transplantation.\n\nIn 2022, a group of international experts led by the Swiss Pediatric Liver Center from the HUG created new guidelines to help identify and treat cholangitis more consistently.\n\nThis study will test how well these new definitions work in real life of hospitals. Over one year, physicians will collect data on children in whom they suspect cholangitis in the first year after their Kasai. The goal is to see whether these new definitions are applicable in the clinical setting.\n\nThe study will involve around 40 patients and will use secure methods to store data. The findings will help improve how cholangitis is diagnosed and treated, making care more effective and consistent for children with biliary atresia.",[28,67],"Cholangitis",[69,70,71],"biliary atresia","Kasai hepatoportoenterostomy","acute cholangitis","NOT_YET_RECRUITING","2025-08-11",{"date":75,"type":43},"2025-08-19",{"date":77,"type":21},"2025-10-01",{"date":79,"type":21},"2026-09-30",{"name":81,"class":50},"University Hospital, Geneva"]