[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"blockades-neuromuscular\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:blockades-neuromuscular":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100646960","upper-vs-lower-extremity-bp-in-spinal-cesarean-using-clearsight-100646960",false,"NCT07685730","Upper vs Lower Extremity BP in Spinal Cesarean Using ClearSight","Comparative Analysis of the Predictive Performance of Noninvasive Beat-by-Beat Blood Pressure and Flow Measurements at the Lower Extremity Versus the Upper Extremity for Neonatal Outcomes Under Spinal Anesthesia for Elective Cesarean Delivery","Inclusion Criteria:\n\n* Age ≥ 18 years old\n* Singleton pregnancy\n* Gestational age ≥ 37 weeks\n* Women undergoing CD under SAB or Combined Spinal-Epidural (CSE) electively.\n* Ability to consent in English and in Spanish language\n\nExclusion Criteria:\n\n* CD under or converted to general anesthesia\n* CD under epidural anesthesia or converted to epidural anesthesia\n* Diabetes Mellitus (DM)\u002FGestational Diabetes Mellitus (GDM)\n* Evidence of unstable cardiac disease other than HDP (including chronic hypertension, gestational hypertension, preeclampsia-eclampsia, and chronic hypertension with superimposed preeclampsia) judged by the investigator to have any impact on BP will make the subject unsuitable for participation in the study\n* Documented fetal anomaly\u002F congenital malformations and genetic syndromes\n* Intrauterine growth retardation\n* Unable to consent in English\u002FSpanish.\n* Prisoners",true,"FEMALE","18 Years",{"count":20,"type":21},327,"ESTIMATED","OBSERVATIONAL","This is a single-center, prospective observational study in patients undergoing cesarean delivery under spinal or combined spinal-epidural anesthesia. It compares whether continuous noninvasive hemodynamic measurements from the lower extremity (toe) better predict neonatal outcomes than upper extremity (arm\u002Ffinger) measurements during spinal-induced hypotension.\n\nParticipants receive standard spinal anesthesia and routine blood pressure management, with additional monitoring using the ClearSight™ system at both upper and lower extremities from before spinal anesthesia through delivery.\n\nThe primary outcome is a composite of neonatal outcomes (APGAR scores, need for respiratory support, cord gases, and NICU admission). Secondary outcomes include maternal side effects and comfort.\n\nOverall, the study evaluates whether lower-extremity hemodynamic monitoring improves detection of clinically relevant hypotension and prediction of neonatal outcomes compared to traditional arm measurements.",[25,26,27],"Anesthesia","Pregnancy Related","Blockades Neuromuscular","RECRUITING","2026-06-29",{"date":31,"type":32},"2026-07-06","ACTUAL",{"date":34,"type":32},"2025-02-06",{"date":36,"type":21},"2029-08-06",{"name":38,"class":39},"Ohio State University","OTHER"]