[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"bone-neoplasm\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:bone-neoplasm":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,41,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100647365","intraoperative-neuromonitoring-of-sacral-reflexes-to-predict-post-operative-function-in-patients-undergoing-sacrectomy-for-pelvic-bone-malignancy-or-patients-undergoing-spinal-procedures-without-sacral-root-involvement-100647365",false,"NCT07707024","Intraoperative Neuromonitoring of Sacral Reflexes to Predict Post Operative Function in Patients Undergoing Sacrectomy for Pelvic Bone Malignancy or Patients Undergoing Spinal Procedures Without Sacral Root Involvement","Phase 2a Prospective Study of Intraoperative Neuromonitoring of the Bulbocavernosus and External Urethral Sphincter Reflexes","Inclusion Criteria:\n\n* Documented informed consent of the participant and\u002For legally authorized representative.\n\n  * Assent, when appropriate, will be obtained per institutional guidelines\n* Age: ≥ 18 years\n* Ability to complete study questionnaires\n* Willingness to comply with all study procedures, including postoperative patient-reported outcome (PRO) assessments\n* Undergoing surgery at City of Hope involving either:\n\n  * Complete or partial sacrectomy for primary or metastatic bone tumors, or\n  * Thoracolumbar intervention in which the sacral roots are not exposed or manipulated (reference cohort)\n\nExclusion Criteria:\n\n* Prior sacrectomy or prior surgery resulting in complete sacral nerve transection\n* For thoracolumbar cohort patients, prior diagnosis or patient report of bowel or bladder dysfunction\n* Cognitive or psychiatric conditions preventing reliable completion of PRO instruments","ALL","18 Years",{"count":19,"type":20},50,"ESTIMATED","INTERVENTIONAL",[23],"NA","This clinical trial tests how well monitoring the sacral reflexes during surgery (intraoperatively) works to predict the post operative function for patients undergoing removal of the lowest part of the spine (sacrectomy) for pelvic bone cancers or patients undergoing spinal procedures. These surgical procedures can lead to damage to sacral root nerves which can result in impairment to the lower extremities, bowel, bladder, and sexual function. Intraoperative monitoring of sacral reflexes can provide objective, real-time information about pelvic nerve function during surgery. This can aid surgical decision-making and help surgeons better prepare patients to understand the changes that may have occurred to their function as a result of surgery. Intraoperative neuromonitoring may work well to predict postoperative function in patients undergoing sacrectomy for pelvic bone malignancy or patients undergoing spinal procedures.",[26,27],"Bone Neoplasm","Metastatic Malignant Neoplasm in the Bone","NOT_YET_RECRUITING","2026-07-10",{"date":31,"type":32},"2026-07-16","ACTUAL",{"date":34,"type":20},"2027-01-10",{"date":36,"type":20},"2029-06-10",{"name":38,"class":39},"City of Hope Medical Center","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":59,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},"100319721","assessment-of-healing-and-function-after-reconstruction-surgery-for-bone-sarcomas-100319721","NCT03442465","Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas","Assessment of Healing and Function After Surgical Reconstruction for Neoplasms Involving Bone","Inclusion Criteria:\n\n* All patients undergoing reconstructive surgery for neoplasms involving bone on the orthopaedic surgery service at MSK\n* Current or prior history of primary neoplasms involving osseous structures, including all subtypes\n* Confirmation of diagnosis that has been performed by the MSK's Department of Pathology via direct review of tissue\u002Fslides\n* Patients must read and understand English\n* Age \\>\u002F=4\n* Patients must read and understand English\n\nExclusion Criteria:\n\n* Patients that weight \\\u003C17 kilograms","4 Years",{"count":50,"type":20},300,"OBSERVATIONAL","The purpose of this study is to look at the amount of function that returns in participants that have reconstruction with bone graft or artificial device and in participants who have tumor surgery plus regenerative osseous surgery.\n\nThe study will look at the level of function for a period of 3 years after the surgery. Another purpose of this study is to look at how well the bone heals in participants undergoing regenerative surgery",[54,55,56,57,58,26],"Bone Sarcoma","Osteosarcoma","Chondrosarcoma","Ewing's Sarcoma","Osseous Sarcoma",[60,61],"18-014","Memorial Sloan Kettering Cancer Center","RECRUITING","2026-04-16",{"date":65,"type":32},"2026-04-17",{"date":67,"type":32},"2018-02-14",{"date":69,"type":20},"2027-02-14",{"name":61,"class":39},5,{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":40},"100392748","novel-imaging-techniques-for-the-characterization-of-musculoskeletal-tumors-ii-100392748","NCT04394052","Novel Imaging Techniques for the Characterization of Musculoskeletal Tumors II","Novel Imaging Techniques for the Characterization of Musculoskeletal Tumors II: Texture Analysis and Artificial Intelligence","TUMOSTEO II","Inclusion Criteria:\n\n* Patients suspected to have a bone or soft-tissue tumor referred for imaging for initial tumors characterization and staging.\n\nExclusion Criteria:\n\n* Pregnancy\n* Breast feeding patients\n* Renal insufficiency\n* Contra indications to MRI or CT\n* Prior surgery or treatment to the evaluated lesion.",{"count":81,"type":20},740,"This study aims at evaluating the value of various artificial intelligence based techniques to improve the characterization and image post-processing for patients with musculoskeletal tumors.",[84,26],"Soft Tissue Neoplasm",[86,87,88,89,90,91],"MRI","CT","Texture analysis","Ultra-high resolution","Tumors","Musculoskeletal","2020-07-20",{"date":94,"type":32},"2020-07-21",{"date":96,"type":32},"2020-06-01",{"date":98,"type":20},"2030-06-01",{"name":100,"class":39},"Central Hospital, Nancy, France"]