[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"breast-hypertrophy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:breast-hypertrophy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100646681","espb-versus-intravenous-lidocaine-for-pain-after-mastopexy-100646681",false,"NCT07687069","ESPB Versus Intravenous Lidocaine for Pain After Mastopexy","Erector Spinae Plane Block (ESPB) Versus Intravenous Lidocaine Infusion for Postoperative Pain and Quality of Recovery in Patients Undergoing Breast Reduction Surgery: A Single Center, Prospective, Randomized Study.","Inclusion Criteria:\n\n* ASA physical status I-III\n* Scheduled for elective breast reduction surgery for non-oncological indications\n\nExclusion Criteria:\n\n* Refusal or inability to provide written informed consent\n* History of chronic somatic or neuropathic pain\n* Current psychiatric disorders or ongoing treatment with antidepressant medications\n* Poorly controlled cardiovascular disease\n* Known allergy or intolerance to amide local anesthetics, including lidocaine and bupivacaine\n* Current alcohol abuse or substance use disorder","FEMALE","18 Years","75 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","Elective breast reduction surgery is associated with moderate-to-severe postoperative pain and a risk of developing chronic postsurgical pain. Enhanced Recovery After Surgery (ERAS) protocols and the Procedure-Specific Postoperative Pain Management (PROSPECT) guidelines emphasize the importance of multimodal analgesia to reduce pain, minimize opioid consumption, and accelerate functional recovery following surgical procedures, including breast surgery.\n\nThe erector spinae plane block (ESPB) has demonstrated effectiveness in breast reduction surgery by reducing postoperative pain intensity, perioperative opioid and non-opioid analgesic consumption, and improving patient satisfaction and recovery time. Furthermore, the use of ESPB has been associated with a reduced incidence of postoperative nausea and vomiting. ESPB is performed with the patient in the sitting position and involves ultrasound-guided identification of the vertebral transverse processes on the side of the block, typically in the interscapular region, followed by the injection of approximately 20 mL of local anesthetic adjacent to the transverse process. When required, the procedure is performed bilaterally at the same vertebral level. ESPB is considered one of the simplest regional anesthesia techniques to perform.\n\nIntravenous lidocaine infusion has been shown to significantly reduce opioid requirements and postoperative pain intensity across a wide range of surgical procedures, particularly in abdominal and breast surgery. Moreover, intraoperative lidocaine infusion has been associated with a reduced risk of chronic postsurgical pain following breast surgery.\n\nThis study was designed to investigate whether intraoperative intravenous lidocaine infusion is non-inferior to ESPB in reducing postoperative pain and improving the quality of recovery following non-oncological breast reduction surgery. Intravenous lidocaine infusion may provide analgesic efficacy and recovery outcomes comparable to those achieved with ESPB, thereby representing a less invasive alternative within a multimodal analgesic strategy.",[27],"Breast Hypertrophy",[29,30,31,32,33],"breast reduction","postoperative pain","erector spine plane block","lidocaine","pain modulation","NOT_YET_RECRUITING","2026-07-03",{"date":37,"type":38},"2026-07-07","ACTUAL",{"date":40,"type":21},"2026-07",{"date":42,"type":21},"2028-08",{"name":44,"class":45},"Centre of Postgraduate Medical Education","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":4,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":46},"100457230","validation-of-scales-in-reconstructive-breast-surgery-100457230","NCT05233891","Validation of Scales in Reconstructive Breast Surgery","ValPlast","Inclusion Criteria:\n\n* Women who have had or will have reconstructive breast surgery in Sahlgrenska university hospital.\n\nExclusion Criteria:\n\n* Do not understand Swedish.","100 Years",{"count":56,"type":21},500,"OBSERVATIONAL","The main purpose of the project is to validate patient reported outcomes measures (PROMs) in reconstructive breast surgery. BREAST-Q will be evaluated for Swedish and Sweden.Hospital Anxiety and Depression Scale (HADS), EuroQol 5D (EQ5D), and SF-36 will be validated for reconstructive breast surgery. In addition, the complication classification system according to Clavien-Dindo will be validated for reconstructive breast surgery.",[60,27],"Breast Cancer",[62,63,64,65],"plastic surgery","breast reconstruction","patient reported outcome","complication","RECRUITING","2025-06-30",{"date":69,"type":38},"2025-07-03",{"date":71,"type":38},"2021-06-21",{"date":73,"type":21},"2027-12-21",{"name":75,"class":76},"Vastra Gotaland Region","OTHER_GOV"]