[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"calcific-tendinitis-of-shoulder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:calcific-tendinitis-of-shoulder":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,71],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100651090","ultrasound-guided-extracorporeal-shock-wave-therapy-for-calcific-tendinitis-100651090",false,"NCT07756307","Ultrasound-Guided Extracorporeal Shock Wave Therapy for Calcific Tendinitis","Effectiveness of Ultrasound-Guided Extracorporeal Shock Wave Therapy for Calcific Tendinitis of the Shoulder: A Randomized Double-Blind Controlled Trial","ESWT","Inclusion Criteria:\n\n* Age between 20 and 70 years\n* Unilateral calcific tendinitis of the shoulder confirmed by clinical physical examination, including a positive Neer's impingement test\n* Symptom duration of more than 3 months\n* Imaging (radiography and\u002For high-resolution ultrasound) demonstrating a calcific deposit within a rotator cuff tendon with a maximal diameter greater than 5 mm\n* Baseline self-reported pain intensity greater than 4 on the Visual Analog Scale (VAS, 0-10)\n* Willing and able to provide written informed consent\n\nExclusion Criteria:\n\n* Concomitant full-thickness rotator cuff tear\n* History of fracture or surgery involving the ipsilateral shoulder\n* Coagulopathy, or anticoagulant therapy that cannot be safely discontinued\n* Pregnancy or breastfeeding\n* Malignancy, particularly involving or adjacent to the shoulder region\n* Local infection or skin lesion at the intended treatment site\n* Injection therapy to the ipsilateral shoulder within the preceding 6 weeks\n* Any other condition that, in the judgment of the investigator, makes the participant unsuitable for participation in the trial","ALL","20 Years","70 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","Calcific tendinitis of the shoulder is a debilitating musculoskeletal condition that significantly impacts the working-age population, typically those between 30 and 60 years of age. Accounting for approximately 7- 17% of shoulder pain complaints, it is characterized by the pathological deposition of calcium hydroxyapatite crystals within the rotator cuff tendons, most notably the supraspinatus. The progression of the disease, particularly during the resorptive phase described in Uhthoff's cycle, is associated with a dramatic increase in intratendinous pressure and severe inflammatory pain, leading to substantial functional impairment and socioeconomic burden. While Extracorporeal Shock Wave Therapy (ESWT) is a well established non-invasive modality known to promote calcific resorption via cavitation effects and mechanotransduction-induced neovascularization, its clinical efficacy remains highly variable across current literature, with success rates ranging widely from 47% to 87%. This inconsistency is largely attributed to the limitations inherent in conventional \"blind\" or landmark-based targeting techniques. Given that calcific deposits are often small, deeply situated, or obscured by the acromion, palpation-guided targeting is frequently unreliable, resulting in suboptimal energy delivery to the pathology and potential collateral damage to surrounding healthy tissues. This one-year research project aims to evaluate the superior efficacy of \"Real-time Ultrasound-Guided\" ESWT compared to conventional methods. The investigators propose a prospective, randomized, double-blind, controlled trial (RCT) that will recruit 60 patients with confirmed calcific tendinitis. Participants will be stratified by Gärtner classification (Type I-III) to ensure balanced morphological distribution and then randomized into either an experimental group receiving Ultrasound-Guided Focused ESWT or a control group receiving Landmark-based\u002FSham ESWT. The study incorporates rigorous methodology, including a priori power analysis for sample size estimation, strict allocation concealment, and assessor blinding. Outcomes will be assessed at baseline, 4, and 12 weeks post-treatment. Primary outcomes include the Constant-Murley Score (CMS) and Visual Analog Scale (VAS), while secondary outcomes involve quantitative ultrasound analysis using ImageJ software to measure the reduction in calcific deposit volume and assess tendon integrity. The investigators hypothesize that the integration of realtime ultrasound guidance will significantly enhance therapeutic precision, leading to higher rates of calcific resorption and functional recovery. The findings are expected to provide high-level evidence to standardize ESWT protocols, thereby advancing the implementation of precision medicine in the field of physical and rehabilitation medicine.",[28],"Calcific Tendinitis of Shoulder",[30,31,32,15],"Calcific tendonitis","shoulder","ultrasound","RECRUITING","2026-08-09",{"date":36,"type":37},"2026-08-12","ACTUAL",{"date":39,"type":37},"2026-06-30",{"date":41,"type":22},"2027-08-31",{"name":43,"class":44},"Taipei Medical University WanFang Hospital","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":45},"100554762","the-effect-of-doppler-ultrasound-on-calcified-tendinitis-100554762","NCT06503302","The Effect of Doppler Ultrasound on Calcified Tendinitis","The Effect of Doppler Ultrasound on Calcified Tendinitis: a Double Blind, Randomized Controlled Trial","Inclusion Criteria:\n\n1. chronic shoulder pain for more than 1 month\n2. shoulder X-ray showed calcified deposit\n\nExclusion Criteria:\n\n1. patient with needle phobia\n2. patient with known allergy to medication like Triamcinolone and Lidocaine","18 Years","80 Years",{"count":56,"type":22},100,[25],"Calcific tendinitis of the shoulder, is a self-limiting disease characterized by the deposition of calcium phosphate crystals in the rotator cuff tendons. Patients will develop complications such as decreased range of motion of the shoulder joint, and thus reducing their quality of life. The most common site of occurrence is 1.5-2 cm away from the supraspinatus tendon insertion site on the greater tuberosity. The primary treatment for calcific tendinitis is conservative, such as non-steroidal anti-inflammatory analgesics for pain relieving, extracorporeal shock wave therapy, subacromial steroid injections, ultrasound-guided barbotage technique for aspirating and washing out calcific deposits. Ultrasound is being used in calcified tendinitis for evaluating its size, location, quality, and also using the color Doppler ultrasonography to evaluate its reactive inflammatory changes. However, the use of color Doppler ultrasonography in diagnosing and treating a shoulder pain with calcification is not being concluded yet. Therefore, the aim of this study is to evaluate the efficacy of color Doppler ultrasonography in calcified tendinitis.",[28],[61],"Doppler ultrasound","2026-04-27",{"date":64,"type":37},"2026-05-01",{"date":66,"type":37},"2024-07-10",{"date":68,"type":22},"2026-06",{"name":70,"class":44},"Taipei Medical University Shuang Ho Hospital",{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":77,"targetDuration":4,"studyType":79,"phases":4,"briefSummary":80,"conditions":81,"keywords":82,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":45},"100624452","a-novel-classification-in-calcific-tendinitis-of-the-shoulder-evaluating-mri-localization-and-related-treatment-strategies-100624452","NCT07409818","A Novel Classification in Calcific Tendinitis of the Shoulder: Evaluating MRI Localization and Related Treatment Strategies","Inclusion Criteria\n\n* Patients who underwent surgical treatment for calcific tendinitis\n* Presence of single or multiple calcific deposits within the rotator cuff tendons\n\nExclusion Criteria\n\n* History of prior ipsilateral shoulder surgery for indications other than calcific tendinitis\n* Revision surgery for calcific tendinitis\n* Incomplete clinical documentation or unavailable MRI data",{"count":78,"type":22},400,"OBSERVATIONAL","Calcific tendinitis of the shoulder is among the frequently encountered shoulder problems. Conservative treatment is often preferred for its management. Persistent pain, impingement symptoms due to large calcific deposits, and extension into the bone are indications for surgical intervention.\n\nAlthough many classification methods for calcific tendinitis have been defined in the literature, none of them is directly related to prognosis, treatment options, or surgical management.\n\nThe aim of this study is to create a new, easy-to-apply, practical, and treatment-related classification system for calcific tendinitis based on the localization of the deposits on MRI.\n\nFurthermore, the aim is to compile the current patient cohort according to this new classification and examine the relationship between the treatment applied and the deposit localization in the proposed classification.",[28],[83,31,84,85,86],"calcific tendinitis","magnetic resonance imaging","calcific deposit","novel classification","2026-02-06",{"date":89,"type":37},"2026-02-13",{"date":91,"type":37},"2025-10-02",{"date":93,"type":22},"2026-10-02",{"name":95,"class":44},"Koç University"]