[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"calcium-silicate-based-sealer-csbs\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:calcium-silicate-based-sealer-csbs":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100659472","efficiency-of-calcium-hydroxide-and-calcium-silicate-based-sealers-in-maxillary-and-mandibular-molars-on-post-root-canal-pain-100659472",false,"NCT07865429","Efficiency of Calcium Hydroxide and Calcium Silicate-Based Sealers in Maxillary and Mandibular Molars on Post-Root Canal Pain","Effectiveness of Calcium Silicate- and Calcium Hydroxide-Based Sealers on Post-Endodontic Pain","CBSS","Inclusion Criteria:\n\n1. Medically healthy patients\n2. Age: 18 to 45 years\n3. Vital Pulp with moderate to severe pre-operative pain score (VAS score 4-10 on EPT).\n4. Symptomatic apical periodontitis\n5. Mandibular and maxillary molars.\n6. Periapical index (PAI) scores 1-2.\n\nExclusion Criteria:\n\n1. Patients experiencing root resorption\n2. Teeth with incomplete root development\n3. Calcified canals\n4. Severe malocclusion\n5. Pregnant or breastfeeding patients\n6. Patients who have used analgesics or anti-inflammatory medications within the past 24 hours","ALL","18 Years","45 Years",{"count":21,"type":22},96,"ESTIMATED","INTERVENTIONAL",[25],"NA","patients reported at department of Operative dentistry diagnosis section , patients coming to operative department of DIDC-DUHS with the chief complain of moderate to severe pain will be assessed .Complete history of each patient will be obtained along with clinical examination including percussion test, presence of swelling, sinus tract and mobility of tooth. Pulp sensitivity will be assessef. Periapical x-ray will be used to evaluate periapical status PAI score. . Following anesthesia, the tooth will be isolated with a rubber dam to maintain a dry operating field. An access cavity will then be prepared. The presence of bleeding within the pulp chamber will be regarded as an indicator of pulp vitality. The (WL) will be established using patency files . An endodontic motor (eight teeth E-connect) will be programmed for root canal instrumentation. Root canals will be irrigated with sodium hypochlorite (NaOCl). Root canals will be dried using paper points, and will take master cone periapical radiograph before final obturation procedure. For the CSBS group (CERASEAL; Meta Biomed Co., Cheongju, Korea), the sealer will be applied and a single cone will be used for obturation. For the CHBS group (Seal apex), the obturation will be completed via cold lateral condensation. The teeth will be restored with composite (LUNA SDI). Single operator will perform the complete procedure. Analgesic ibuprofen 400 mg (Brufen) will be prescribed to the patient in case of severe pain",[28],"Calcium Silicate Based Sealer (CSBS)","NOT_YET_RECRUITING","2026-10-04",{"date":32,"type":33},"2026-10-08","ACTUAL",{"date":35,"type":22},"2026-10-15",{"date":37,"type":22},"2027-06-01",{"name":39,"class":40},"Dow University of Health Sciences","OTHER"]