[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"carbonyl-stress\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:carbonyl-stress":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":5},"100652028","effects-of-flavonoid-foods-on-carbonyl-stress-100652028",false,"NCT07767149","Effects of Flavonoid Foods on Carbonyl Stress","Effects of Flavonoid-rich Foods on Carbonyl Stress","Inclusion Criteria:\n\n* 1\\. Age 25-70 years 2. BMI between 18 and 30 3. Have no known allergy to test food 4. have no known allergies to green tea, apples, blueberries, soy milk, and pineapples 5. Be not engaging in high-intensity exercise 6. Having blood and urine clinical tests in the normal range. 7. Be not taking antibiotics for six months 8. Be not currently taking medication\n\n  1. No taking any prescription drugs\n  2. If supplements were taken, flavonoid-enriched supplements (see list below) should be avoided.\n\n     Major brands Notes Soy Isoflavones All flavonoid-enriched supplements should be avoided. Lipo-Flavonoid Citrus Bioflavonoids Complex Super Flavonoids Super Antioxidants Quercetin Supplement Essential-C and flavonoids Milk Thistle Other flavonoids supplements, including but not limited: Luteolin, Rutin, etc\n  3. No any drugs or supplements within three weeks of the experiment 9. Be nonsmoking 10. Have no alcoholic intoxication\n\n  \u003C!-- -->\n\n  1. No alcoholic addiction\n  2. \\\u003C 3-4 drinks per week (less than 2 glasses (300 mL) per drink)\n  3. No alcohol within 3 three weeks of the experiment 11. Have no extended exposure to industrial wastes\n\nExclusion Criteria:\n\n* 1\\. Disease: gout, heart disease, peripheral vascular disease, degenerative kidney, degenerative liver, diabetes, GI disorders, or endocrine disorders 2. Cancer patients\n\n  1. Currently diagnosed cancer patients will be excluded.\n  2. Medication free for \\>2 years could be considered.",true,"ALL","25 Years","70 Years",{"count":21,"type":22},36,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized crossover study will compare low- and high-flavonoid diets in healthy adults to identify flavonoid-derived biomarkers in urine and plasma. Using targeted LC-MS metabolomics, researchers will measure known and novel flavonoid metabolites and evaluate whether a higher flavonoid intake reduces carbonyl stress markers, including reactive carbonyl species (RCS) and advanced glycation end products (AGEs).",[28,29,30],"Human Health","Flavonoids","Carbonyl Stress",[32,33,34,35,36],"flavonoids","Carbonyl stress","Advanced glycation end products (AGEs)","Metabolomics","Reactive carbonyl species (RCS)","RECRUITING","2026-08-11",{"date":40,"type":41},"2026-08-17","ACTUAL",{"date":43,"type":22},"2026-09-02",{"date":45,"type":22},"2027-12-31",{"name":47,"class":48},"North Carolina Agriculture & Technical State University","OTHER"]