[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cardiopulmonary-exercise-test-interpretation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cardiopulmonary-exercise-test-interpretation":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100657171","ai-assisted-anaerobic-threshold-interpretation-in-cardiopulmonary-exercise-testing-100657171",false,"NCT07833137","AI-Assisted Anaerobic Threshold Interpretation in Cardiopulmonary Exercise Testing","A Randomized Two-Period Crossover Reader Study of Artificial Intelligence-Assisted Anaerobic Threshold Interpretation in Cardiopulmonary Exercise Testing","PACE-Reader","Inclusion Criteria:\n\n* Age 18 years or older.\n* Licensed physician or physician enrolled in a recognized postgraduate clinical training program at the study institution.\n* Eligible for one of the two prespecified seniority strata: senior physicians are attending physicians or above with at least 5 years of independent CPET interpretation experience; junior physicians are residents or specialty trainees with less than 5 years of independent CPET interpretation experience.\n* Able to interpret CPET examinations and use the study interface after standardized orientation.\n* Willing and able to complete both study periods and the prespecified washout interval.\n* Provides written informed consent.\n\nExclusion Criteria:\n\n* Direct involvement in development, training, hyperparameter selection, or checkpoint selection of the PACE-Former model.\n* Prior access to the study case libraries, reference-standard annotations, or model outputs for the study examinations.\n* Unable to complete the required interpretation tasks or the 14 ± 3 day washout interval.\n* Withdrawal of consent before completion of study procedures.",true,"ALL","18 Years",{"count":21,"type":22},16,"ESTIMATED","INTERVENTIONAL",[25],"NA","This prospective randomized two-period crossover reader study will evaluate whether assistance from a frozen artificial intelligence model improves physicians' interpretation of the anaerobic threshold (AT) in cardiopulmonary exercise testing (CPET). Sixteen physicians, including 8 senior and 8 junior readers, will each interpret 150 de-identified CPET examinations once without AI assistance and once with AI assistance. The primary outcome is the within-physician difference in absolute AT localization error between the assisted and unassisted conditions. Secondary outcomes include signed timing error, agreement on whether AT is present, estimates within 15 and 30 seconds of the reference, inter-reader reliability, interpretation time, and whether the effect of AI assistance differs by physician seniority.",[28],"Cardiopulmonary Exercise Test Interpretation",[30,31,32,33,34,35],"Artificial Intelligence","Anaerobic Threshold","Cardiopulmonary Exercise Testing","Clinical Decision Support","Reader Study","Human-AI Collaboration","NOT_YET_RECRUITING","2026-09-16",{"date":39,"type":40},"2026-09-22","ACTUAL",{"date":42,"type":22},"2026-09-25",{"date":44,"type":22},"2026-11-25",{"name":46,"class":47},"Shanghai Zhongshan Hospital","OTHER"]