[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cardiorespiratory-failure\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cardiorespiratory-failure":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":38,"overallStatus":48,"whyStopped":4,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":53,"completionDateStruct":55,"leadSponsor":57,"locationsCount":60},"100654748","hermes-quality-and-safety-of-advanced-respiratory-support-during-patient-transport-100654748",false,"NCT07805603","HERMES: Quality and Safety of Advanced Respiratory Support During Patient Transport","The HERMES Program: An International Multicenter Prospective Study of Quality and Safety During Transport of Patients Receiving Advanced Respiratory Support","HERMES","Inclusion Criteria:\n\n* Patients undergoing a clinically indicated prehospital, interhospital, or intrahospital transport.\n* Patients receiving advanced respiratory support at the beginning of the transport episode, including at least one of the following:\n\nHigh-flow nasal oxygen (HFNO); Noninvasive ventilation (NIV), including continuous positive airway pressure or bilevel positive airway pressure; Invasive mechanical ventilation.\n\n* Respiratory support and transport management determined by the treating clinical team according to routine clinical practice and local institutional protocols.\n* Availability of the minimum data required to document the transport episode, including respiratory-support modality and transport outcome.\n* Provision of informed consent by the patient or legally authorized representative when required by the applicable local ethics committee and national regulations, or inclusion under an approved waiver or alternative consent procedure where applicable.\n\nExclusion Criteria:\n\n* Transport performed without HFNO, NIV, or invasive mechanical ventilation.\n* Transport in which respiratory-support modality or another therapeutic intervention is assigned specifically by the HERMES study protocol rather than by routine clinical care.\n* Transport episodes for which the minimum dataset required to determine the primary outcome cannot be obtained.\n* Withdrawal of consent when consent is required and withdrawal occurs before the participant's data can be included according to applicable regulations.\n* Transport episodes entered in error or duplicate records referring to the same transport event.","ALL",{"count":19,"type":20},565,"ESTIMATED","OBSERVATIONAL","The HERMES Phase III study is an international, multicenter, prospective observational investigation designed to characterize the quality and safety of patient transport during advanced respiratory support.\n\nThe study will enroll patients undergoing prehospital, interhospital, or intrahospital transport while receiving advanced respiratory support, including high-flow nasal oxygen (HFNO), noninvasive ventilation (NIV), or invasive mechanical ventilation, as determined by routine clinical practice. The study protocol will not assign respiratory-support modalities, transport strategies, or therapeutic interventions.\n\nThe primary objective is to prospectively evaluate clinical, technical, organizational, and transport-related factors associated with the safe continuation of respiratory support throughout patient transport. Data collection will include patient characteristics, respiratory-support modality and settings, transport characteristics, physiologic monitoring, transport-team composition, oxygen and electrical power resources, equipment-related events, interruptions or modifications of respiratory support, clinical deterioration, rescue interventions, escalation of respiratory support, and other transport-associated adverse events.\n\nHERMES Phase III constitutes the prospective multicenter component of a broader research program that previously included an international survey of respiratory-support transport practices and an exploratory prospective feasibility evaluation of portable external power during ambulance transport.",[24,25,26,27,28,29,30,31,32,33,34,35,36,37],"Acute Respiratory Failure","Respiratory Insufficiency","Respiratory Distress","Critical Illness","Chronic Respiratory Failure","Cardiorespiratory Failure","Mechanical Ventilation","Noninvasive Ventilation","High-Flow Nasal Oxygen Therapy","Advanced Respiratory Support","Patient Transport","Transport of Critically Ill Patients","Patient Safety During Transport","Patient Safety",[34,39,40,41,31,42,43,44,45,37,46,47],"Intrahospital Transport","Interhospital Transport","Prehospital Transport","High-Flow Nasal Oxygen","Invasive Mechanical Ventilation","Transport Safety","Respiratory Support","Critical Care Transport","Electrical Power Continuity","NOT_YET_RECRUITING","2026-09-01",{"date":51,"type":52},"2026-09-04","ACTUAL",{"date":54,"type":20},"2026-12-31",{"date":56,"type":20},"2027-12-31",{"name":58,"class":59},"Medipol University","OTHER",4]