[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cardiovascular-syndrome-metabolic\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cardiovascular-syndrome-metabolic":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100554514","effects-of-intermittent-dietary-restriction-on-cardiometabolic-risk-in-school-aged-children-100554514",false,"NCT06500078","Effects of Intermittent Dietary Restriction on Cardiometabolic Risk in School-aged Children","Effects of Intermittent Dietary Restriction on Cardiometabolic Risk in School-aged Children: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 7-18 years at baseline.\n* At least one of the following cardio-metabolic abnormalities:\n\n  1. Prediabetes (Impaired fasting glucose: 5.6 ≤ fasting blood glucose level ≤ 6.9 mmol\u002FL; or Impaired glucose tolerance: 7.8 ≤ blood glucose level after 2 hours postprandial ≤ 11.0 mmol\u002FL).\n  2. Lipid abnormalities (High-density lipoprotein cholesterol ≤ 1.04 mmol\u002FL; or Low-density lipoprotein cholesterol ≥ 3.37 mmol\u002FL; or Triglycerides ≥ 1.70 mmol\u002FL, or Total cholesterol ≥ 5.18 mmol\u002FL).\n  3. Elevated blood pressure (Systolic\u002Fdiastolic blood pressure consistently higher than the 90th percentile for gender, age, and height; or systolic\u002Fdiastolic blood pressure ≥ 120\u002F80 mmHg).\n\nExclusion Criteria:\n\n* Previously diagnosed with heart failure, severe malnutrition, immune deficiency, liver or kidney disease, cancer, or other diseases deemed unsuitable for participation.\n* Had a history of bariatric surgery.\n* Used weight loss pills or supplements in the last three months.\n* Other situations unsuitable for participation.","ALL","7 Years","18 Years",{"count":20,"type":21},324,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized trial aims to evaluate the health-promoting effects of intermittent dietary restrictions, including intermittent low-carbohydrate diet (ILCD) and calorie restriction (ICR), in school-aged children with cardiometabolic risk (CMR) compared with general health education based on dietary and physical activity guidelines for Chinese children.",[27],"Cardiovascular Syndrome, Metabolic",[29,30,31,32],"Intermittent carbohydrate restriction","Intermittent calorie restriction","Cardiometabolic risk","Children","RECRUITING","2026-07-02",{"date":36,"type":37},"2026-07-06","ACTUAL",{"date":39,"type":37},"2024-07-13",{"date":41,"type":21},"2027-12-31",{"name":43,"class":44},"Children's Hospital of Fudan University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":58,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":68,"leadSponsor":70,"locationsCount":45},"100548091","high-intensity-interval-traininghiit-on-cardio-metabolic-risk-in-school-age-children-100548091","NCT06416488","High-Intensity Interval Training(HIIT) on Cardio-metabolic Risk in School-age Children","The Effect of High-Intensity Interval Training(HIIT) on Cardio-metabolic Indicators in School-age Children With High Cardiovascular Diseases Risk--a Randomised Intervention Trial","Inclusion Criteria:\n\n* Aged 7-18 years at baseline.\n* At least one of the following cardio-metabolic abnormalities:\n\n  1. Prediabetes (Impaired fasting glucose: 5.6 ≤ fasting blood glucose level ≤ 6.9 mmol\u002FL; or Impaired glucose tolerance: 7.8 ≤ blood glucose level after 2 hours postprandial ≤ 11.0 mmol\u002FL).\n  2. Lipid abnormalities (High-density lipoprotein cholesterol ≤ 1.04 mmol\u002FL; or Low-density lipoprotein cholesterol ≥ 3.37 mmol\u002FL; or Triglycerides ≥ 1.70 mmol\u002FL, or Total cholesterol ≥ 5.18 mmol\u002FL).\n  3. Elevated blood pressure (Systolic\u002Fdiastolic blood pressure consistently higher than the 90th percentile for gender, age, and height; or systolic\u002Fdiastolic blood pressure ≥ 120\u002F80 mmHg).\n* Written consent from participants and their guardians.\n\nExclusion Criteria:\n\n* Previously diagnosed with heart failure, severe malnutrition, immune deficiency, liver or kidney disease, cancer, or other diseases deemed unsuitable for participation.\n* Taking weight loss drugs, or undergone weight loss surgery.\n* Attending behavior-based intervention programs (exercise or diet) within a year.\n* Regular HIIT (at least once per week).\n* Secondary obesity, such as neuropsychiatric disorders, endocrine disorders, sleep apnea syndrome, or other conditions.\n* Unable to take interventions due to health conditions, such as joint diseases, fractures, injuries.\n* Other situations unsuitable for participation.",{"count":54,"type":21},336,[24],"This study aims to evaluate the health promotion effects of high-intensity interval training (HIIT) intervention on school-age children who are at high risk for cardiovascular disease (CVD), as well as the long-term adherence and acceptability of HIIT in this population for future application.",[27],[59,60,61,62,63],"Cardiovascular diseases","Metabolic disorders","High-Intensity Interval Training","School-aged children","Childhood obesity","2025-12-09",{"date":66,"type":37},"2025-12-16",{"date":39,"type":37},{"date":69,"type":21},"2028-09",{"name":43,"class":44}]