[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chemoprophylaxis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chemoprophylaxis":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100659579","phase-4-these-studies-that-evaluated-the-efficacy-of-antibiotics-for-leptospirosis-treatment-100659579",false,"NCT07865156","These Studies That Evaluated the Efficacy of Antibiotics for Leptospirosis Treatment.","The Study of the Efficacy of Doxycycline for Chemoprophylaxis Acute Leptospirosis Infection During Rainy Season in Thailand","Inclusion Criteria:\n\n* High-risk exposure typically refers to water or soil - particularly wet ground at workplace and\u002For contact with animal water reservoir\n\nExclusion Criteria:\n\n* Body temperature higher than 38 °C\n* Patients were confirmed to have leptospirosis within 3 months\n* Pregnancy or breastfeeding\n* Allergy to doxycycline\n* Cirrhosis Child-Pugh C, acute hepatitis, persistent elevated liver enzymes AST\u002FALT \\> 3 times\n* Doxycycline Interactions: phenytoin, carbamazepine, barbiturates, warfarin methotrexate, cyclosporin",true,"ALL","18 Years",{"count":20,"type":21},1000,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","The goal of this randomized controlled trial is to study antibiotic chemoprophylaxis to prevent leptospirosis of high-risk populations.\n\nThe main question it aims to answer is : Does the efficacy of chemoprophylaxis regimens to prevent prevent leptospirosis?",[27,28],"Leptospirosis","Chemoprophylaxis","NOT_YET_RECRUITING","2026-10-05",{"date":32,"type":33},"2026-10-08","ACTUAL",{"date":35,"type":21},"2026-11-01",{"date":37,"type":21},"2027-01-31",{"name":39,"class":40},"Chulalongkorn University","OTHER"]