[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-graft-versus-host-disease-in-eye\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-graft-versus-host-disease-in-eye":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":5},"100654152","observational-cohort-study-on-ocular-chronic-graft-versus-host-disease-100654152",false,"NCT07794800","Observational Cohort Study on Ocular Chronic Graft-Versus-Host Disease","A Multicenter, Prospective, Non-Interventional Observational Cohort Study on Ocular Chronic Graft-Versus-Host Disease After Hematopoietic Stem Cell Transplantation - The Bright Study","Inclusion Criteria:\n\n* Age ≥14 years, both genders eligible;\n* First allogeneic hematopoietic stem cell transplantation;\n\n  * 100 days post-transplantation, with donor hematopoietic stem cell engraftment confirmed;\n* The subject or their legally authorized representative has provided full informed consent, signed the informed consent form, and is willing to complete subsequent follow-up visits\n\nExclusion Criteria:\n\n* Preexisting moderate-to-severe ocular surface disease prior to transplantation;\n* Active ocular infection;\n* Presence of other ocular conditions that, in the opinion of the ophthalmologist, may significantly affect the diagnosis of chronic ocular graft-versus-host disease, the evaluation of ocular surface parameters, or the completion of long-term follow-up;\n* Patients with active hematologic malignancies.","ALL","14 Years",{"count":19,"type":20},340,"ESTIMATED","2 Years","OBSERVATIONAL","This study is a multicenter, prospective, observational cohort study designed to enroll a total of 340 patients undergoing allogeneic hematopoietic stem cell transplantation. Through comprehensive evaluations by hematology departments, ophthalmology departments, and patient-reported outcomes, the study aims to assess patient-reported outcomes, overall incidence, risk factors, and other clinical outcomes in patients with chronic ocular graft-versus-host disease following allogeneic hematopoietic stem cell transplantation.",[25],"Chronic Graft Versus Host Disease in Eye","RECRUITING","2026-08-27",{"date":29,"type":30},"2026-08-31","ACTUAL",{"date":32,"type":30},"2026-06-01",{"date":34,"type":20},"2030-06-01",{"name":36,"class":37},"Ruijin Hospital","OTHER"]