[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-kidney-diease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-kidney-diease":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,55],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":33,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100650590","improving-patient-centered-care-for-underserved-older-african-american-patients-with-cardiovascular-comorbidities-100650590",false,"NCT07748858","Improving Patient-Centered Care for Underserved Older African American Patients With Cardiovascular Comorbidities","Improving Patient-Centered Care for Underserved Older African American Patients With Cardiovascular Comorbidities: A Pilot Study of the Patient Priorities Care Approach at Cooper Green Mercy Health Services Authority (PPC-HEART)","PPC Heart","Inclusion Criteria:\n\n* greater than or equal to 50 years old\n* at least one CVD (i.e., coronary artery disease, hypertension, heart failure, arrhythmias, cardiomyopathy, peripheral artery disease, stroke, and valvular heart disease)\n* at least one coexisting chronic condition (i.e., inflammatory joint disease, COPD\u002Fasthma, diabetes, chronic kidney disease, and cancer one-year post-treatment)\n* a caregiver of a participant, or a provider who serves this population.\n\nExclusion Criteria:\n\n* Axis I psychiatric (schizophrenia, bipolar disorder), dementia, suicidal ideation,\n* active substance use disorder nursing home or assisted living facility residence.","ALL","50 Years","99 Years",{"count":21,"type":22},29,"ESTIMATED","OBSERVATIONAL","This is formative evaluation trial guided by the Values Clarification Theory25 and the Cultural Values Theory26, with specific aims to: Aim 1. Develop a culturally appropriate version of the PPC Approach for older AAs with CVCs by assembling a community advisory group of 3 primary care clinicians, 3 older AA patients with CVCs, and 3 AA persons who care for AA patients with CVCs to solicit feedback on the PPC Approach. Aim 2. Determine the acceptability (e.g., program appraisal interviews) and feasibility (e.g., avg. length of program sessions, program participation rate, study completion rate) of the PPC Approach among a sample 20 of under-resourced older southern AA patients with CVCs receiving primary care at Cooper Green Mercy Health Services Authority. Aim 3. Examine the ability of participants to complete pre- and post-test (8 weeks post-baseline) measures of perception of care, treatment burden, shared decision-making, and patient-clinician communication exchange.",[26,27,28,29,30,31,32],"Cardiovascular","Comorbidity","Diabetes","Inflammatory Joint Diseases","Chronic Kidney Diease","Chronic Obstructive Pulmonary Disease (COPD)","Cardiovascular Disease",[34,35,36,37,38,39,40,41],"Cardiovascular Diseases","Chronic Kidney Disease","Chronic Obstructive Pulmonary Disease","Patient-Centered Care","Shared Decision Making","Care Coordination","Older Adults","Multiple Chronic Conditions","RECRUITING","2026-07-31",{"date":45,"type":46},"2026-08-06","ACTUAL",{"date":48,"type":46},"2026-05-01",{"date":50,"type":22},"2027-06",{"name":52,"class":53},"University of Alabama at Birmingham","OTHER",1,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":4,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":17,"minAge":63,"maxAge":4,"enrollmentInfo":64,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":66,"conditions":67,"keywords":72,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":5},"100630965","chronic-kidney-disease-and-metabolic-disorders-in-the-elderly-100630965","NCT07494526","Chronic Kidney Disease and Metabolic Disorders in the Elderly","Research on the Prevention, Control, and Intelligent Management Decision-Making for Comorbidities of Chronic Kidney Disease and Metabolic Disorders in the Elderly","For Sub-cohort 1, the inclusion and exclusion criteria are as follows:\n\nInclusion Criteria:\n\n1. Baseline age ≥ 65 years.\n2. Availability of baseline data on serum creatinine and at least one urinary protein measurement.\n3. Urinary protein measurements include: UACR, UPCR, 24-hour urine protein quantification, and urine protein dipstick test.\n4. Baseline date requirement: Between January 1, 2010, and December 31, 2025.\n5. Follow-up requirement meeting at least one of the following: At least one serum creatinine measurement with an interval of ≥ 6 months after baseline. Occurrence of a primary endpoint event (new-onset CKD).\n\nExclusion Criteria:\n\nPresence of CKD at baseline, defined as: Glomerular filtration rate (eGFR) \\\u003C 60 ml\u002F(min·1.73m²) or positive urine protein; or the presence of an ICD-10 diagnostic code for CKD in medical records.\n\nFor Sub-cohort 2 (CKD Patients), the inclusion and exclusion criteria are as follows:\n\nInclusion Criteria:\n\n1. Baseline age ≥ 65 years.\n2. Meeting the diagnostic criteria for CKD: Glomerular filtration rate (eGFR) \\\u003C 60 ml\u002F(min·1.73m²) or urine protein (UACR ≥ 30 mg\u002Fg); or based on ICD-10 codes.\n3. Baseline date requirement: Between January 1, 2010, and December 31, 2025.\n4. Follow-up requirement meeting at least one of the following:\n\nOccurrence of a primary endpoint event (mortality, ESRD); At least one serum creatinine measurement with an interval of ≥ 6 months after baseline.\n\nExclusion Criteria:\n\n1. End-stage renal disease (ESRD) at baseline (eGFR \\\u003C 15 ml\u002F(min·1.73m²), or prior receipt of kidney transplant or dialysis), based on ICD codes).\n2. Diagnosis of acute kidney injury (AKI) within the preceding 3 months.\n3. New York Heart Association (NYHA) Class III or IV heart failure or occurrence of acute myocardial infarction within the preceding 6 months.\n4. Child-Pugh Class B or C liver cirrhosis.\n5. Malignant neoplasm.",true,"65 Years",{"count":65,"type":22},100000,"The goal of this observational study is to investigate the impact of metabolic comorbidities on outcomes in elderly Chinese adults, through two parallel sub-cohorts: one comprising elderly individuals without chronic kidney disease (CKD) at baseline, and one comprising elderly patients with established CKD.\n\nThe main questions it aims to answer are:\n\nDo metabolic diseases (diabetes, hypertension, hyperlipidemia, hyperuricemia, calcium-phosphorus disorders) increase the risk of incident CKD, major adverse cardiovascular events (MACE), and all-cause mortality in elderly individuals without CKD at baseline? What are the optimal diagnostic thresholds and criteria for CKD in the elderly population? How do metabolic comorbidities affect long-term outcomes - including all-cause mortality, end-stage renal disease (ESRD), and cardiovascular events - in elderly patients with established CKD? What is the comorbidity profile and disease burden of elderly CKD patients in China?\n\nParticipants in both sub-cohorts will:\n\nUndergo baseline assessments including laboratory tests and clinical evaluations.\n\nProvide longitudinal follow-up data through scheduled clinic visits and medical record linkage.\n\nContribute to a large-scale cohort of 100,000 elderly participants across multiple centers in China.",[30,68,69,70,71],"Diabetes Mellitus","Hypertension","Hyperlipidemia","Hyperuricemia",[73,74,75],"chronic kidney disease","elderly","metabolic disorders","NOT_YET_RECRUITING","2026-03-20",{"date":79,"type":46},"2026-03-27",{"date":81,"type":22},"2026-04",{"date":83,"type":22},"2028-12",{"name":85,"class":53},"Chinese PLA General Hospital"]