[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-masticatory-myofascial-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-masticatory-myofascial-pain":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100659228","masticatory-muscle-activity-using-a-24-hour-wearable-device-100659228",false,"NCT07861906","Masticatory Muscle Activity Using a 24-Hour Wearable Device","Reevaluating the Role of Masticatory Muscle Activity in Chronic Myofascial Pain Using a 24-Hour Wearable Device","For the chronic myofascial pain group, the Inclusion Criteria are:\n\n* Patients of record of the dental institutes at Midwestern University, College of Dental Medicine-Illinois\n* Receiving a diagnosis of chronic masticatory myofascial pain according to the Diagnostic Criteria for Temporomandibular Disorders after a consult with the orofacial pain specialist\n* Reporting painful symptomatology on the day of the monitoring\n* Age 18+\n* Ability to connect to the Internet\n* Ability to read and speak English or Italian language\n\nExclusion Criteria:\n\n* Patients undergoing orthodontic treatments\n* Not on stable medication regimen on the day of the monitoring\n* Starting to wear an occlusal appliance on the day of the monitoring\n* Changed occlusal appliance within the past 3 months\n\nFor the healthy control group, Inclusion Criteria are:\n\n* Sex and age-matched otherwise healthy adults (without any pain-related masticatory myofascial pain upon examination)\n* Patients of record of the dental institutes at Midwestern University, College of Dental Medicine-Illinois\n* Ability to connect to the Internet\n* Ability to read and speak English language\n\nExclusion criteria:\n\n* Patients undergoing orthodontic treatments\n* Not on stable medication regimen on the day of the monitoring\n* Starting to wear an occlusal appliance on the day of the monitoring\n* Changed occlusal appliance within the past 3 months",true,"ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","OBSERVATIONAL","Patients with chronic masticatory myofascial pain (MFP) often report that stress and parafunctional oral habits aggravate their pain, consistent with the widespread belief that stress and parafunctional habits lead to increased\u002Fsustained jaw muscle activity and subsequent pain. Yet, these assumptions have never been directly tested, given the lack of tools to measure masticatory muscle activity in real-world settings. This protocol describes a prospective, longitudinal, case-control observational study that will enroll 50 patients total (25 with clinician-diagnosed chronic MFP and 25 age- and sex-matched healthy controls) from the university-based dental clinics at Midwestern University, Illinois. Consenting participants will be instructed to complete a baseline biopsychosocial battery assessing self-reported awake and sleep bruxism (using the Oral Behavior Checklist, OBC), anxiety\u002Fdepression symptoms (using the Patient Health Questionnaire, PHQ-4), perceived stress (using the Perceived Stress Scale, PSS), insomnia symptoms (using the Insomnia Severity Index, ISI) and chronic pain intensity (using the Graded Chronic Pain Scale, GCPS). All participants will be provided a 24-hour electromyograph (EMG) device (dia-BRUXO, Biotech-Novations, Sanremo, Italy) placed on the left masseter, recording jaw muscle activity. Brief ecological momentary assessments will be sent during the 24-hour period, assessing pain intensity, self-reported parafunctional habits, stress and anxiety. The primary aim will be to establish if self-reported awake and sleep bruxism and\u002For biopsychosocial distress are as-sociated with EMG-recorded masticatory muscle activity. The secondary aim will test if masticatory muscle activity is associated with jaw pain intensity.",[25],"Chronic Masticatory Myofascial Pain",[27,28,29,30,31,32,33],"masticatory myofascial pain","temporomandibular disorders","ecologic momentary assessment","ambulatory EMG activity","orofacial pain","parafunctional activities","clenching","RECRUITING","2026-10-01",{"date":37,"type":38},"2026-10-06","ACTUAL",{"date":40,"type":38},"2025-06-01",{"date":42,"type":21},"2027-09-30",{"name":44,"class":45},"Midwestern University","OTHER"]