[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-medical-illness\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-medical-illness":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100647092","sanamente-a-peer-led-program-to-reduce-health-disparities-in-rural-latinoa-communities-100647092",false,"NCT07705776","SanaMente: A Peer-Led Program to Reduce Health Disparities in Rural Latino\u002Fa Communities","SanaMente: A Peer-Led, Evidence-Based Mental Health and Lifestyle Program to Reduce Health Disparities in Rural Latino\u002Fa Communities","SanaMente","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Identify as Hispanic\u002FLatino\u002Fa.\n* Patients of La Clínica del Pueblo in Carbondale, Colorado.\n* Spanish-speaking (bilingual Spanish-English speakers are eligible).\n* Interest in improving your physical and emotional well-being.\n* Are currently managing or are at risk for chronic medical or metabolic conditions (e.g., diabetes, cardiovascular disease, liver, or kidney conditions), but a diagnosis is not required.\n* Experiencing or at risk for stress, low mood, or anxiety (formal diagnosis not required)\n* Willingness and ability to participate in the SanaMente program.\n* Willing to provide a release of information authorizing study staff to communicate with La Clínica del Pueblo in the event that a participant endorses suicidality or if it becomes necessary to share relevant medical information to ensure participant safety and appropriate care.\n\nExclusion Criteria:\n\n* Individuals who are unable to provide informed consent.\n* Individuals who are unwilling or unable to participate in the group-based or one-to-one SanaMente sessions.",true,"ALL","18 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to evaluate the feasibility, acceptability, and preliminary effectiveness of the SanaMente peer-led mental health and lifestyle program for rural Latino\u002Fa adults with chronic medical conditions and mental health concerns. The main questions it aims to answer are:\n\n* Is the SanaMente program feasible and acceptable for rural Latino\u002Fa adults with chronic medical conditions and mental health concerns?\n* Does participation in the SanaMente program improve mental health outcomes (depression, anxiety, and stress), healthy lifestyle behaviors (sleep, physical activity, and nutrition), and overall well-being?\n\nThis is a single-arm pilot study without comparison group.\n\nParticipants will:\n\n* Participate in the 6-8 week SanaMente peer-led group program.\n* Complete surveys at baseline, mid-program, and post-program assessing mental health, lifestyle behaviors, overall well-being, and program satisfaction.\n* Complete an exit survey and have the option to participate in a focus group to provide feedback on the program's usability, acceptability, perceived impact, and suggestions for improvement.",[28,29,30],"Depression and\u002For Anxiety in the Mild-to-moderate Range","Stress (Psychology)","Chronic Medical Illness",[32,33,34,35],"rural","Peer-led intervention","Chronic disease","Latino\u002Fa mental health","RECRUITING","2026-07-10",{"date":39,"type":40},"2026-07-15","ACTUAL",{"date":42,"type":40},"2026-03-06",{"date":44,"type":22},"2026-12-10",{"name":46,"class":47},"University of Colorado, Boulder","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":18,"minAge":56,"maxAge":19,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":72,"overallStatus":84,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":48},"100630104","comparative-effectiveness-of-sparcs-and-unified-protocol-for-youth-with-chronic-medical-conditions-and-trauma-related-distress-100630104","NCT07483333","Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress","Supporting Purposeful Interventions & Resilience In Trauma (SPIRIT) Program: Implementing Trauma-Specific Screening and Stratified Interventions for Youth With a Chronic Medical Condition","Inclusion Criteria:\n\n* Youth (aged 8-18 years) who received a SPIRIT program psychological trauma screening and were deemed clinically appropriate for SPIRIT group therapy. Clinically appropriate means the youth can historically engage in a group setting (e.g., school, camp, therapy group) without significant disruption to the group process or other participants.\n* Youth and parent\u002Flegal guardian are willing and able to provide informed consent\u002Fassent for randomization.\n* Youth and parent\u002Flegal guardian are fluent in English or Spanish.\n* Youth is not currently engaged in individual therapy at the time of enrollment (per patient\u002Fparent report).\n\nExclusion Criteria:\n\n* Wards of the state or DCFS youth in care.\n* Youth with reported or observed symptoms that would significantly impair group therapy engagement, including but not limited to: intellectual disability, moderate-to-severe autism spectrum disorder, active suicidal ideation, uncontrolled psychosis, or other acute psychiatric symptoms that could disrupt the group process.\n* Regular use of alcohol or other substances that interfere with participation or disrupt the group process.\n* Youth requiring immediate higher-level psychiatric care (e.g., intensive outpatient programming, partial hospitalization, inpatient psychiatric admission, or residential treatment) at the time of first randomization.","8 Years",{"count":58,"type":22},400,[25],"The goal of this clinical trial is to compare the effectiveness of trauma-focused therapies for improving mental health symptoms and daily functioning in youth with chronic medical conditions who have experienced psychological trauma and trauma-related distress. The study evaluates two evidence-based cognitive-behavioral therapies - Structured Psychotherapy for Adolescents Responding to Chronic Stress (SPARCS) and the Unified Protocol (UP) - delivered in group and individual formats to determine which approach, or combination of approaches, best reduces trauma symptoms and supports coping and adjustment. The study will also help researchers understand how to best support youth who continue to experience distress after an initial round of therapy.\n\nThe main questions it aims to answer are:\n\n* Does SPARCS group therapy or UP group therapy lead to greater improvements in trauma symptoms and functional impairment?\n* For youth who do not show enough improvement after group therapy, does adding SPARCS or UP individual therapy lead to better outcomes?\n* Which sequence of group and individual therapies leads to the greatest improvements in trauma symptoms and functioning?\n\nResearchers will compare two evidence-based therapies currently offered at Ann \\& Robert H. Lurie Children's Hospital of Chicago. Youth will first be randomly assigned to receive either SPARCS or UP in a group format. After completing group therapy, youth who still need additional support will be randomly assigned again to receive individual or family therapy using SPARCS or UP. This stepwise approach will help identify which sequence of therapies leads to the best overall outcomes for youth.\n\nParticipants will:\n\n* Take part in group therapy sessions using either SPARCS or UP\n* For those needing additional support after group therapy, participate in individual SPARCS or UP therapy\n* Complete brief assessments of mental health and daily functioning at enrollment, and every 12 weeks thereafter for 48 weeks, as part of their regular care through Ann \\& Robert H. Lurie Children's Supporting Purposeful Interventions \\& Resilience in Trauma (SPIRIT) program",[62,63,64,65,66,67,30,68,69,70,71],"Trauma Exposure","Trauma","Trauma and Stressor Related Disorder","Mental Health Functioning","Chronic Medical Conditions","Chronic Medical Condition","Posttraumatic Stress Disorder PTSD","Posttraumatic Stress Disorders","Posttraumatic Stress Symptoms","Posttraumatic Stress",[73,74,75,76,77,78,79,80,81,82,83],"pediatric trauma","posttraumatic stress disorder","chronic medical conditions","pediatrics","trauma symptoms","trauma and stressor related disorder","trauma informed care","Sequential, Multiple Assignment Randomized Trial","Supporting Purposeful Interventions and Resilience in Trauma","Unified Protocol","Structured Psychotherapy for Adolescents Responding to Chronic Stress","NOT_YET_RECRUITING","2026-03-16",{"date":87,"type":40},"2026-03-19",{"date":89,"type":22},"2026-07",{"date":91,"type":22},"2029-09-29",{"name":93,"class":47},"Anthony Vesco"]