[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-prostatitischronic-pelvic-pain-syndrome-cpcpps\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-prostatitischronic-pelvic-pain-syndrome-cpcpps":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100646902","clinical-evaluation-of-the-efficacy-and-safety-of-a-medical-device-in-the-form-of-rectal-suppositories-prospidol-for-the-treatment-of-symptoms-associated-with-chronic-prostatitischronic-pelvic-pain-syndrome-100646902",false,"NCT07685847","Clinical Evaluation of the Efficacy and Safety of a Medical Device in the Form of Rectal Suppositories (Prospidol®) for the Treatment of Symptoms Associated With Chronic Prostatitis\u002FChronic Pelvic Pain Syndrome.","Inclusion Criteria:\n\n* male subjects aged between 18 and 60;\n* clinical presentation typical of prostatitis and a clinical diagnosis of chronic prostatitis type IIIa or IIIb (CP\u002FCPPS) for at least 3 months;\n* no treatment for at least 2 months;\n* PSA \\\u003C 3 ng\u002FmL;\n* digital rectal examination negative for nodules or BPH;\n* negative microbiological tests on urine and seminal fluid;\n* baseline score on the validated Italian version of the NIH-CPSI pain domain questionnaire \\> 7 or total NIH-CPSI score \\> 15;\n* digital rectal examination not suggestive of prostate cancer.\n\nExclusion Criteria:\n\n* patients with signs of infection and a PSA level \\> 3 ng\u002Fml;\n* other active prostate conditions;\n* patients with active neoplastic, neurodegenerative or immunological conditions, those who are immunocompromised, or those who are already taking supplements or functional foods for any reason;\n* patients undergoing treatment with systemic or topical corticosteroids;\n* patients who will not sign the informed consent form;\n* patients unable to participate in a clinical trial for any reason (e.g. psychiatric patients, those with cancer, on dialysis, or with severe liver or kidney failure);\n* patients with allergies to any of the components of the medical device (MD) under investigation.","MALE","18 Years","60 Years",{"count":19,"type":20},40,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to evaluate whether a medical device is effective and safe in treating chronic prostatitis\u002Fchronic pelvic pain syndrome (CP\u002FCPPS) in adult men.\n\nThe main questions it aims to answer are:\n\n* Does the treatment reduce pain symptoms (measured by NIH-CPSI score) by more than 30% after one month?\n* Does the treatment improve urinary symptoms, quality of life, and sexual function?\n* What adverse events or side effects occur during treatment? Researchers will conduct a multicenter, open-label study involving 40 participants diagnosed with CP\u002FCPPS. All participants will receive the same treatment, and their outcomes will be monitored over time.\n\nParticipants will:\n\nUse one suppository daily for 10 days each month for 3 months Attend clinical visits at the start of the study and after 30, 60, and 90 days Complete validated questionnaires (NIH-CPSI, IPSS, SF-36, IIEF) at each visit Report any side effects or symptoms throughout the study At the end of the study, researchers will analyze symptom improvement, quality of life changes, and treatment tolerability.",[26],"Chronic Prostatitis\u002FChronic Pelvic Pain Syndrome (CP\u002FCPPS)",[28,29,30,31],"prostate","prostatitis","suppository","CP\u002FCPPS","RECRUITING","2026-06-29",{"date":35,"type":36},"2026-07-06","ACTUAL",{"date":38,"type":36},"2025-09-01",{"date":40,"type":20},"2026-09",{"name":42,"class":43},"S&R Farmaceutici S.p.A.","INDUSTRY",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":4},"100617863","acupuncture-for-erectile-dysfunction-100617863","NCT07324148","Acupuncture for Erectile Dysfunction","Acupuncture for Erectile Dysfunction Among Patients With Chronic Prostatitis\u002FChronic Pelvic Pain Syndrome: a Clinical Trial","Inclusion Criteria:\n\n* Conforms to the diagnosis of CP\u002FCPPS and pED at the same time;\n* Aged between 18-50 years old;\n* 8≤IIEF-5 score≤21\n* Have a fixed sexual partner and a regular sexual intercourse of ≥1 time\u002Fweek during treatment period;\n* Voluntarily sign an informed consent form.\n\nExclusion Criteria:\n\n* Patients with drug-induced or organic ED.\n* The existence of lesions that may affect erectile function, such as penile cancer, penile sclerosis, penile anatomical deformity, testicular cancer, urinary system stones or neuropathy, etc.\n* History of trauma or surgery in pelvic region.\n* Patients with hypogonadism.\n* Usage of drugs or therapies that relieve CP\u002FCPPS or ED symptoms in the previous 1 month.\n* Have received hormonal or psychiatric drugs in the previous 3 months.\n* Bladder outlet obstruction, overactive bladder, neurogenic bladder, interstitial cystitis, glandular cystitis, sexually transmitted diseases, bladder tumors, prostate cancer, penile cancer, penile stone, other types of prostatitis.\n* With a residual urine ≥100ml.\n* Symptomatic urinary tract infection.\n* Diseases affecting the function of the lower urethra, such as multiple sclerosis, senile dementia, Parkinson's disease, spinal cord injury, caua equina nerve injury, stroke and multisystem atrophy, etc.\n* Severe diseases in heart, lung, brain, liver, kidney and hematopoietic system , mental illness and obvious cognitive function disorders.\n* Patients with poor compliance","50 Years",{"count":53,"type":20},100,[23],"Chronic Prostatitis\u002FChronic Pelvic Pain Syndrome (CP\u002FCPPS) is a prevalent chronic urological disease. CP\u002FCPPS severely impacts patients' quality of life. It is characterized by recurrent pelvic floor pain, lower urinary tract symptoms, and often accompanied by psychological issues and sexual dysfunction (duration ≥3 months, no confirmed infection\u002Fpathology).\n\nThe investigators have completed a large-sample, multi-center randomized controlled trial (RCT) involving 440 patients with CP\u002FCPPS before. The clinical trial confirmed the sustained efficacy of acupuncture for the symptoms of pain, lower urinary tract symptoms, and anxiety and depression among patients with CP\u002FCPPS. However, the trial revealed no significant improvements in sexual dysfunction in the acupuncture group compared to the sham acupuncture group after 8 weeks of treatment.To address this limitation, the current study is designed, which aims to optimize the clinical acupuncture protocol for CP\u002FCPPS and evaluate whether it can enhance outcomes for psychogenic erectile dysfunction (ED) associated. Additionally, mass cytometry and liquid suspension chip technology will be used to explore systemic and local immune mechanisms underlying acupuncture's effects for CP\u002FCPPS. Functional magnetic resonance imaging (fMRI) and metabolomics will be integrated to analyze patients' systemic states from central nervous system and metabolic perspectives, comprehensively elucidating the multi-dimensional mechanisms by which acupuncture alleviates CP\u002FCPPS.",[26,57,58],"Erectile Dysfunctions","Acupuncture","NOT_YET_RECRUITING","2026-01-06",{"date":62,"type":36},"2026-01-08",{"date":64,"type":20},"2026-01-01",{"date":66,"type":20},"2028-06-30",{"name":68,"class":69},"Guang'anmen Hospital of China Academy of Chinese Medical Sciences","OTHER"]