[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-spinal-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-spinal-pain":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,77],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100575405","time-to-step-up-to-stepped-care-a-novel-strategy-for-cognitive-behavioral-therapy-for-insomnia-in-chronic-spinal-pain-100575405",false,"NCT06771856","Time to Step Up to Stepped Care: A Novel Strategy for Cognitive Behavioral Therapy for Insomnia in Chronic Spinal Pain","Time to Step Up to Stepped Care: A Novel Strategy for Cognitive Behavioral Therapy for Insomnia in Chronic Spinal Pain - a Randomized Controlled Trial","StepUp","Inclusion Criteria:\n\nInsomniacs (18-65y\u002Fo), with an Insomnia Severity Index score ≥15 (i.e., at least moderate insomnia) suffering from CSP, defined as non-specific spinal pain of at least 3 month's duration, currently seeking care for CSP, with a pain severity of ≥3\u002F10 on the Brief Pain Inventory are recruited. In the absence of other intrin-sic sleep disorders and shift work, insomnia is defined as \\>30 minutes sleep latency and\u002For minutes awake after sleep onset for \\>3 days\u002Fweek for \\>3 months.\n\nExclusion Criteria:\n\nHaving severe underlying sleep pathology, being pregnant or given birth in the preceding year, suffering from a chronic condition which is currently causing other pain complaints, or suffering from severe psychological or psychiatric dis-eases, dementia or cognitive impairment. Eligible participants are asked not to start new treatments or medication, and continuing the usual non-physical thera-py care (6 weeks prior to and during study participation to obtain a steady state). A sleep-related anamnesis and a polysomnography assessment are performed to determine and exclude severe underlying comorbid sleep disorders.","ALL","18 Years","65 Years",{"count":21,"type":22},129,"ESTIMATED","INTERVENTIONAL",[25],"NA","Chronic spinal pain (i.e., chronic neck pain and chronic low back pain) are highly prevalent, and are known for their immens personal and socio-economic burden. Chronic spinal pain is impacted by many aspects, and in this story, insomnia plays an important role. Clinical insomnia symptoms are very common in people suffering from chronic spinal pain, and the presence of insomnia is known to aggravate the chronic spinal pain symptoms. While research shows that tackling insomnia in these patients is helpful for these patients, the availability of cognitive behavioral therapy, the golden standard to treat insomnia, is unfortunately extremely limited. Therefore this study aims to investigate whether a stepped care approach to cognitive behavioral therapy is a solution to this problem.",[28],"Chronic Spinal Pain",[30,31,32],"insomnia","stepped care","cognitive behavioral therapy","RECRUITING","2026-08-18",{"date":36,"type":37},"2026-08-19","ACTUAL",{"date":39,"type":37},"2025-02-01",{"date":41,"type":22},"2027-12",{"name":43,"class":44},"Vrije Universiteit Brussel","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":75,"locationsCount":45},"100615478","protocol-for-a-randomized-controlled-trial-comparing-the-effectiveness-of-mechanical-diagnosis-and-therapy-versus-generalized-exercise-for-reducing-pain-in-surgeons-with-chronic-spinal-pain-100615478","NCT07293130","Protocol for a Randomized Controlled Trial Comparing the Effectiveness of Mechanical Diagnosis and Therapy Versus Generalized Exercise for Reducing Pain in Surgeons With Chronic Spinal Pain","Protocol for a Pragmatic, Randomized Controlled, Parallel-group Superiority Trial Comparing the Effectiveness of Mechanical Diagnosis and Therapy Versus Generalized Exercise for Reducing Pain in Surgeons With Chronic Spinal Pain and a Directional Preference","Inclusion Criteria:\n\n* Age 25-70 years\n* Currently working as a resident, fellow, or attending surgeon\n* Chronic spinal pain (low back, thoracic, or neck) lasting more than 3 months\n* Demonstrated directional preference on standardized clinical examination (i.e., movement in a specific direction reduces symptoms)\n* Sufficient proficiency in Danish to complete trial questionnaires\n* Willing and able to attend treatment sessions at designated physiotherapy clinics\n* Provide written informed consent\n\nExclusion Criteria:\n\n* Serious spinal pathology (e.g., fracture, malignancy, infection, inflammatory disease)\n* Cauda equina syndrome\n* Significant neurological deficits requiring urgent medical attention\n* Any diagnosed medical condition preventing safe participation in physical activity\n* Sick leave longer than 6 months at baseline\n* Pregnancy or having given birth within the past 3 months\n* Scheduled for major surgery within the next 3 months\n* Current participation in structured physiotherapy or spinal interventions outside the trial protocol","25 Years","70 Years",{"count":56,"type":22},62,[25],"Surgeons frequently experience chronic spinal pain due to prolonged static postures and repetitive movements during surgical procedures. Exercise therapy is recommended, but it is unclear which type of exercise is most effective for this population.\n\nThis randomized clinical trial will compare Mechanical Diagnosis and Therapy (MDT), also known as the McKenzie Method, with a structured program of generalized exercise in surgeons with chronic spinal pain who demonstrate a directional preference (i.e., movement in a specific direction that reduces symptoms).\n\nParticipants will be randomly assigned to one of the two interventions and followed for 26 weeks. The primary outcome is spinal pain intensity at 12 weeks measured on a 0-10 scale. Secondary outcomes include function, quality of life, and psychological factors.\n\nThis pragmatic trial is conducted in outpatient physiotherapy settings and aims to determine whether an individualized exercise approach (MDT) is more effective than generalized exercise in this occupational group.",[28],[61,62,63,64,65,66,67],"spinal pain","chronic pain","musculoskeletal pain","occupational health","surgeons","rehabilitation","exercise","NOT_YET_RECRUITING","2026-03-18",{"date":71,"type":37},"2026-03-20",{"date":73,"type":22},"2026-03-30",{"date":41,"type":22},{"name":76,"class":44},"Claus Kjærgaard",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":23,"phases":86,"briefSummary":87,"conditions":88,"keywords":89,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":103},"100503830","rtms-and-steroid-joint-steroid-injection-in-chronic-spinal-pain-100503830","NCT05840354","RTMS and Steroid Joint Steroid Injection in Chronic Spinal Pain","Repetitive Transcranial Magnetic Stimulation Combined with Steroid Joint Injection for the Treatment of Chronic Spinal Pain: Protocol for a Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n* Currently receiving recurrent steroid joint injections for control of chronic spinal pain at the St. Joseph's Health Centre Pain Clinic in London, Ontario, Canada,\n* Have pain in the spinal region of an intensity ≥4 out of 10 in the week before your most recent steroid joint injection,\n* Have received at least 2 steroid joint injections within the last 12 months at regular intervals\n* Have had a consistent medication regimen for the past 3 months.\n\nExclusion Criteria:\n\n* Unable to read, understand, and speak English and are not able to give consent\n* Known or suspected serious spinal pathology (tumour, fracture, dislocation, scoliosis)\n* Spinal surgery in the past 12 months\n* History of uncontrolled mental health condition(s)\n* Meet any specific rTMS-related exclusion criteria listed on the safety screening questionnaire (S1; Rossi et al., 2008).",{"count":85,"type":22},40,[25],"Chronic spinal pain (CSP) is one of the most common chronic pain conditions globally. Steroid joint injections (SJI) are a routine treatment option for patients with CLBP that is recalcitrant to other treatments. However, SJI has been shown to have limited long-term efficacy with patients often requiring another injection within months to adequately control pain. One option to prolong the analgesic effects of SJI is to use a type of noninvasive brain stimulation called repetitive transcranial magnetic stimulation (rTMS). Previous studies have shown rTMS may be capable of providing long-term pain relief in patients with chronic back pain. However, the literature on rTMS in patients with CSP is limited and no study has explored rTMS in patients receiving recurrent SJI for pain control.\n\nIn this pilot randomized controlled trial study, we'll be investigating if combining rTMS with SJI in CSP individuals will enhance or prolong the analgesic effects of SJI alone.\n\nThe investigators hypothesize that a combined rTMS and SJI intervention will be feasible, tolerable, and safe and will have larger and longer-lasting effects on CSP than a sham rTMS and SJI intervention.",[28],[90,91,92,93,62],"repetitive transcranial magnetic stimulation","steroid joint injection","inflammatory markers","inflammation","2025-02-03",{"date":96,"type":37},"2025-02-05",{"date":98,"type":37},"2023-06-20",{"date":100,"type":22},"2025-12-31",{"name":102,"class":44},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's",2]