[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"claustrophobia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:claustrophobia":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,46,72,98],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100535845","comparing-radiotherapy-immobilization-systems-for-anxious-hnc-patients-100535845",false,"NCT06257121","Comparing Radiotherapy Immobilization Systems for Anxious HNC Patients","A Pilot Study to Assess the Use of Surface-guided Radiotherapy in Head and Neck Cancer Patients Who Suffer From Anxiety","CRISP","Inclusion Criteria:\n\n* Eighteen years of age or older\n* Able to fluently speak, read and write French or English\n* Histologically confirmed head and neck cancer\n* Patients treated with radiotherapy as primary treatment\n* Identified as having moderate mask anxiety \u002F claustrophobia (i.e. a score of 10 or more on the Generalized Anxiety Disorder 7 item (GAD-7) questionnaire and \u002F or a score of 28 or more on the Claustrophobia questionnaire (CLQ) suffocation subscale and \u002F a score of 24 or more on the CLQ restriction subscale\n* An Eastern Cooperative Oncology Group (ECOG) Performance Status grade of 0-2\n* Able to understand and sign consent form\n* Patients must be willing to comply with treatment plan and other study procedures\n\nExclusion Criteria:\n\n* Patients with significantly altered mental status or with psychological, familial, sociological or geographical condition potentially hampering compliance with the study\n* Patients who cannot stay still during fraction because of a disorder or physical condition (e.g., Parkinson's disease)","ALL","18 Years",{"count":20,"type":21},15,"ESTIMATED","INTERVENTIONAL",[24],"NA","Background: Radiotherapy is a mainstay of treatment for ENT cancers, and its indication is frequent. Patients are positioned and immobilized using a thermoplastic mask, which is attached to the treatment table for the duration of each daily treatment. The mask's purpose is to prevent patient movement and ensure reproducible positioning. The advantages of using thermoplastic masks come at a cost for many patients. It is well established that mask fixation and mask anxiety are major concerns for patients, adversely affecting their quality of life and hindering treatment compliance. Surface-guided radiotherapy (SGRT) enables patients to be positioned and their movements monitored in real time during treatment. This technique has become more widely available in recent years, and is attractive because it does not involve ionizing radiation. However, although preliminary data have suggested a potential reduction in anxiety, this technique has not been evaluated for ENT RT in anxious\u002Fclaustrophobic patients who cannot tolerate immobilization masks.\n\nObjective: Investigators propose a pilot study to evaluate the feasibility and tolerability of using SGRT to manage position for patients with ENT cancer who report claustrophobia\u002Fanxiety.\n\nMethodology: 15 participants will be recruited by the treating radiation oncologist from among patients scheduled to undergo radiation therapy at CHUM for their ENT cancer and identifying as claustrophobic\u002Fanxious. Participants who consent will be scheduled to undergo their radiotherapy using SGRT. Patients will be systematically treated with Volumetric Modulated Arc Therapy (VMAT) using SGRT on the linear accelerator with the Optical Surface Management System (OSMS) for the duration of the radiotherapy.\n\nMeasures: Patients' anxiety will be assessed using the GAD-7 and the CLQ throughout the treatment process. The feasibility and accuracy of radiotherapy treatment will be assessed using planning and daily pre-treatment examinations. In addition, skin toxicity will be assessed weekly.\n\nAnalyses: 1) Descriptive analyses, i.e. frequencies for categorical variables and means and standard deviations for continuous variables. 2) Estimation of confidence intervals.\n\nAnticipated outcomes: Completion of this pilot project will enable investigators to plan and refine the methodological and organizational aspects for a large-scale study, i.e., a Phase III clinical trial comparing the use of SGRT with the use of a thermoplastic immobilization mask for anxious patients.",[27,28,29],"Head and Neck Cancer","Claustrophobia","Anxiety",[31,29,28,32,33],"Head and neck cancer","Surface-guided imagery","Radiation therapy","NOT_YET_RECRUITING","2026-08-17",{"date":37,"type":38},"2026-08-19","ACTUAL",{"date":40,"type":21},"2026-10-15",{"date":42,"type":21},"2029-02-01",{"name":44,"class":45},"Centre hospitalier de l'Université de Montréal (CHUM)","OTHER",{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":4},"100616724","phase-2-evaluation-of-the-effectiveness-of-a-cardiac-coherence-exercise-on-mri-success-and-image-quality-in-claustrophobic-patients-100616724","NCT07309328","Evaluation of the Effectiveness of a Cardiac Coherence Exercise on MRI Success and Image Quality in Claustrophobic Patients","COCARI","Inclusion Criteria:\n\n* Patient aged 7 years or older\n* Undergoing a 1.5T or 3T MRI scan as part of routine care\n* Self-reported claustrophobia on the imaging department admission form\n* Explicit consent to participate in the study, provided by the patient or a legal representative (for minors)\n* Affiliated with or beneficiary of a social security system\n\nExclusion Criteria:\n\n* Patient under legal protection or guardianship\n* Pregnant or breastfeeding woman\n* Inability to complete questionnaires and\u002For perform the cardiac coherence exercise as judged by the investigator","7 Years",{"count":55,"type":21},220,[57,58],"PHASE2","PHASE3","Claustrophobia, an intense fear of confined spaces, can significantly impair the success of MRI examinations by causing patient movement or early termination of the scan, leading to poor image quality. Cardiac coherence, a breathing technique aimed at synchronizing heart rate and reducing anxiety, has shown benefits in stress management. This randomized controlled trial aims to evaluate whether the use of a guided cardiac coherence exercise during MRI can improve exam success rates and image quality in self-reported claustrophobic patients compared to standard care (cartoons for children, music for adults). The primary outcome is the proportion of interpretable MRI scans with good-quality images, assessed blindly by a radiologist. Secondary outcomes include exam duration, use of the emergency call button, patient satisfaction, and perceived comfort. A total of 220 patients aged 7 years and older will be enrolled over 12 months at the Fondation Adolphe de Rothschild Hospital.",[28,61],"MRI","2025-12-29",{"date":64,"type":38},"2025-12-30",{"date":66,"type":21},"2026-01",{"date":68,"type":21},"2027-12",{"name":70,"class":71},"Fondation Ophtalmologique Adolphe de Rothschild","NETWORK",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":22,"phases":82,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":97},"100615762","internet-based-cognitive-behavioral-therapy-for-mri-related-anxiety-100615762","NCT07296822","Internet-Based Cognitive Behavioral Therapy for MRI-Related Anxiety","A Randomized Controlled Trial of Internet-Based Cognitive Behavioral Therapy for MRI-Related Anxiety","MRTightxiety","Inclusion Criteria:\n\n* self-perceived problems with doing MRI examinations\n\nExclusion Criteria:\n\n* difficulty understanding written text\n* severe mental health problems",{"count":81,"type":21},60,[24],"The aim of the study is to investigate whether internet-based cognitive behavioural therapy (iCBT) can help patients who have difficulty undergoing magnetic resonance imaging (MRI). The main question to be answered is\n\n\\- Can patients undergo MRI with less anxiety using iCBT?\n\nThe patients will undergo a four-week treatment that includes information about MRI, anxiety management, relaxation and retention. The end goal is to simulate an MRI scan in a mock scanner where participants can report their anxiety. Half of the participants will be randomized to receive the treatment before (intervention group) the simulated MRI scan and half will receive the treatment after the simulated MRI scan (control group). Up to 60 patients will be included plus some pilot patients.",[29,28,85],"Magnetic Resonance Imaging (MRI)","RECRUITING","2025-12-08",{"date":89,"type":38},"2025-12-22",{"date":91,"type":38},"2025-05-01",{"date":93,"type":21},"2026-12-31",{"name":95,"class":96},"Johan Kihlberg","OTHER_GOV",1,{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":4,"eligibilityCriteria":104,"healthyVolunteers":105,"sex":17,"minAge":106,"maxAge":107,"enrollmentInfo":108,"targetDuration":4,"studyType":110,"phases":4,"briefSummary":111,"conditions":112,"keywords":113,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":97},"100506571","premedication-for-claustrophobic-patients-for-mri-scan-100506571","NCT05876117","Premedication for Claustrophobic Patients for MRI Scan","Clonidine and Lorazepam Premedication for Claustrophobic Patients During MRI Scan","Inclusion Criteria:\n\n* diagnosed with claustrophobia\n* previous incomplete MRI because of claustrophobia\n* adult patients\n* good treatment compliance\n* reliable Claustrophobia Questionnaire (CLQ) diary\n* reliable General Anxiety Disorder Questionnaire (GAD) diary\n* informed consent for diary review\n* consent for clinical record quality assurance review\n\nExclusion Criteria:\n\n* poor treatment compliance\n* cognitive disorder\n* inability to provide consent\n* major neuropsychiatric disorder\n* unreliable diary\n* cannabis use\n* excessive alcohol intake\n* previous adverse\u002Fallergic reactions to clonidine\n* previous adverse\u002Fallergic reactions to lorazepam",true,"20 Years","99 Years",{"count":109,"type":21},50,"OBSERVATIONAL","Claustrophobia is an irrational fear of restriction and suffocation. It is a specific phobia, according to DSM 5. Claustrophobic patients may fear that restriction of their limbs will hinder their ability to move quickly towards safety. MRI may trigger claustrophobia, because this diagnostic procedure involves a patient laying in a narrow tube. Premedication before MRI scan may occasionally reduce claustrophobia.\n\nProspective observational crossover study of claustrophobic patients who are undergoing MRI scan. At alternate MRI scan sessions, each patient receives rotational premedication using Lorazepam 1mg; or Clonidine tablet 0.2mg; or combined Clonidine 0.2mg + Lorazepam 1mg.\n\nPatient will use Claustrophobia Questionnaire, a validated tool, to collect data on the days before and after each MRI scan. CLQ is a patient-administered tool used to assess claustrophobia. In addition, patient will use General Anxiety Disorder Questionnaire, a validated tool, to collect data on the days before and after each MRI scan. GAD-7 is a patient-administered tool that is used to assess anxiety.",[28],[114],"Claustrophobia MRI","2025-01-23",{"date":117,"type":38},"2025-01-27",{"date":119,"type":38},"2020-07-04",{"date":121,"type":21},"2025-12-31",{"name":123,"class":45},"Salem Anaesthesia Pain Clinic"]