[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"colonic-cancer\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:colonic-cancer":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,69],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100647901","abdominal-massage-after-colon-surgery-for-cancer-100647901",false,"NCT07713472","Abdominal Massage After Colon Surgery for Cancer","Benefits of Abdominal Massage After Colon Surgery for Cancer Following an ERAS Protocol (MATRAC_Ter): a Multicenter, Prospective, Randomized Clinical Trial","MATRAC_Ter","Inclusion Criteria:\n\n* Adults programmed to undergo surgery involving right, transverse or left colectomy due to cancer with anastomosis, regardless the approach (laparoscopy.\n* Laparotomy and Robot-assisted). Patients must be able to follow the colorectal surgery unit's ERAS protocol.\n* All included patients are required to have signed a study specific written informed consent form prior to inclusion in the trial.\n\nExclusion Criteria:\n\n* Patients required emergency surgery (obstruction or peritonitis),\n* A stoma for whatever reason,\n* Rectal cancer,\n* BMI \\> 40,\n* Psychiatric disorders,\n* An associated procedure, extensive resection,\n* Pregnancy, deprivation of liberty by judicial or administrative decision, or being under legal protection and patients with a hierarchical link to the principal investigator.","ALL","18 Years",{"count":20,"type":21},225,"ESTIMATED","INTERVENTIONAL",[24],"NA","Postoperative ileus is a transient gastrointestinal dysmotility following abdominal surgery that leads to bloating, abdominal distention, visceral pain, nausea, vomiting, and delayed passage of flatus and stool. This paralytic state lasts longer when surgery involves the distal rather than the proximal digestive tract. Its incidence following colorectal surgery is between 10% and 30%. The main factors of postoperative ileus include age, predisposed constipation, method of anesthesia, type of surgical approach, perioperative analgesia, inflammatory reactions, and the psychopathology of the patient.\n\nEnhanced recovery after surgery (ERAS) provides patients with optimal means to counteract or minimize the deleterious effects of surgery, in particular toward minimizing postoperative ileus. Expert consensus among surgeons, anesthesiologists, physiotherapists, dieticians, and other team members has been reached that stated 24 clinical statements concerning preoperative, peroperative and postoperative periods that should be included in current rehabilitation programs in colorectal surgery.\n\nIn China, massage, a 3000-year-old therapy guided by the theory of Yin and Yang, is widely used to treat various diseases. Chapelle and Bowe showed that abdominal massage reduced experimental postoperative ileus in a rat model and suggested that the effect was due to the attenuation of inflammation.\n\nAbdominal massage has not widely been applied after colorectal surgery. Due to the scarcity of literature on abdominal massage, it has never been considered to be part of ERAS recommendations in colorectal surgery. Nevertheless, massage involving profound maneuvering of the viscera through abdominal palpation and breathing has been used as part of the local postoperative protocol in our department for many years with interesting results, and no complication has been reported. To our knowledge, only one study has explored the effect of mechanical abdominal massage on the duration of ileus after colectomy.\n\nThe aim of this prospective, multicenter randomized controlled trial (RCT) is to compare return of intestinal transit using the GI-2 criteria as defined by the time to first defecation and time to tolerance of solid food following the operation in two groups of patients following an ERAS protocol for colonic cancer surgery, one with and the other without early postoperative abdominal massage.",[27],"Colonic Cancer",[29,30,31,32,33],"Postoperative ileus","Surgery","Colonic cancer","Abdominal massage","Physiotherapy","NOT_YET_RECRUITING","2026-07-16",{"date":37,"type":38},"2026-07-20","ACTUAL",{"date":40,"type":21},"2026-07",{"date":42,"type":21},"2028-08-31",{"name":44,"class":45},"University Hospital, Grenoble","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":46},"100376726","butyrophilins-role-in-colon-cancer-100376726","NCT04185272","Butyrophilins Role in Colon Cancer","Role of Butyrophilins in Colon Cancers Aggressiveness Evaluation","Inclusion Criteria:\n\n* Patient is older than 18 years old,\n* Signed participation consent,\n* Non-metastatic colon cancer immediately resectable or metastatic and liver synchronous for which it was decided a combined colic and liver surgery (metastatic patient at the outset) in multidisciplinary consultation meeting.\n* Performance Status (PS) 0 or 1\n* affiliated to the social security or beneficiary\n\nExclusion Criteria:\n\n* Rectal cancer, colon cancer recurrence\n* Emergency of colon cancer Surgery\n* History of inflammatory disease of the digestive tract (Crohn's disease or ulcerative colitis)\n* Patient who received neoadjuvant therapy other than chemotherapy\n* Patient treated with immune-suppressors or long-course corticosteroids \\\u003C12 months\n* Pregnant women or likely to be pregnant (without effective contraception) or breastfeeding,\n* Person in urgent situation, person under legal protection measure, or unable to express his \u002F her consent,\n* Impossibility of submitting to the medical examination of the test for geographical, social or psychological reasons",{"count":55,"type":21},200,[24],"quantification of BTNL molecules in colon cancer in order to determinate if their could be used as a prognostic marquer",[27],"RECRUITING","2025-06-13",{"date":62,"type":38},"2025-06-15",{"date":64,"type":38},"2020-06-30",{"date":66,"type":21},"2028-06",{"name":68,"class":45},"Institut Paoli-Calmettes",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":78,"phases":4,"briefSummary":79,"conditions":80,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":87,"leadSponsor":89,"locationsCount":46},"100472603","chinese-colorectal-cancer-database-100472603","NCT05434026","Chinese Colorectal Cancer Database","CCCD","Inclusion Criteria:\n\n* adenocarcinoma of the colon by biopsy\n* tolerable to surgery\n* be able to understand and willing to participate in this trial with signature\n\nExclusion Criteria:\n\n* can not tolerate the surgery\n* history of serious mental illness\n* the researchers believe the patients should not enrolled in",{"count":77,"type":21},200000,"OBSERVATIONAL","1. To establish the Chinese people's own clinical data database of colorectal cancer, reflecting the law and characteristics of colorectal cancer patients in China.\n2. Based on colorectal cancer surgery, collect clinical data, especially data on clinical manifestations, complications, laboratory tests, auxiliary examinations, postoperative clinical effects, surgical complications, and colorectal cancer recurrence, so as to lead the direction of clinical practice and academic research of colorectal cancer surgery in China. It provides a certain basis for future research on colorectal cancer.\n3. Provide academic consultation and data support to national health authorities.",[27,81,82],"Rectal Cancer","Prospective Studies","2022-08-01",{"date":85,"type":38},"2022-08-03",{"date":85,"type":21},{"date":88,"type":21},"2032-06-22",{"name":90,"class":45},"Beijing Friendship Hospital"]