[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"comatose\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:comatose":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100651475","kinetics-and-prognostic-value-of-neurofilament-light-in-post-cardiac-arrest-a-prospective-multicenter-study-100651475",false,"NCT07760636","Kinetics and Prognostic Value of NeuroFilament Light in Post-cardiac Arrest: A Prospective Multicenter Study","CINEFIL","Inclusion Criteria:\n\n* Patients admitted to the ICU for cardiac arrest,\n* Patients who regained consciousness following in-hospital or out-of-hospital cardiac arrest,\n* Patients in a coma upon arrival in the ICU, defined by a Glasgow Coma Scale (GCS) score \\\u003C8,\n* Patients included in the AfterROSC2 cohort,\n\nExclusion Criteria:\n\n* Terminally ill patients (death expected within 3 hours of admission to the ICU),\n* Minors,\n* Patients under legal guardianship,\n* Pregnant women,\n* Patients not enrolled in a social security program,\n* Prior inclusion in the CINEFIL study,\n* Restriction of active therapies prior to the first NFL biomarker assay,\n* Objection by a family member or trusted person, if present","ALL","18 Years",{"count":19,"type":20},270,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to assess the prognostic value of absolute value and kinetic of neurofilament light chain (NFL) collected at different time points (at admission, 12h, 24h, 48h, 72h, 96h, and day 7 after ICU admission) in predicting poor and good neurological outcome in comatose patients after cardiac arrest.",[24,25,26,27],"Cardiac Arrest (CA)","Intensive Care Unit (ICU) Admission","Return of Spontaneous Circulation","Comatose",[29,30,31,32,33],"Cardiac arrest","Coma","Neuroprognostication","Biomarkers","Neurofilament light chain","NOT_YET_RECRUITING","2026-08-10",{"date":37,"type":38},"2026-08-12","ACTUAL",{"date":40,"type":20},"2026-09",{"date":42,"type":20},"2028-06",{"name":44,"class":45},"Assistance Publique - Hôpitaux de Paris","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":46},"100631918","neuro---prognostication-using-late-somatosensory-evoked---potentials-100631918","NCT07506928","NEURO - Prognostication Using Late Somatosensory Evoked - Potentials","NEURO-PULSE","Inclusion Criteria:\n\n* Patients must be aged 18 years or over;\n* Patients must be admitted to the intensive care unit with a cerebrovascular pathology;\n* Patients must be in a comatose state with a Glasgow score strictly less than 8, 24 hours after stopping sedation.\n* Representative of the patient informed of the research and not objecting to it, information and collection of the participant's non-objection if recovery of the ability to understand the content of the information note,\n* The patient is a recipient of or affiliated with a social security scheme.\n\nExclusion Criteria:\n\n* Bilateral lesions of the motor cortex or cortico-spinal fasciculus,\n* Cutaneous infection of the scalp or any other lesion making surface electroencephalography impossible,\n* Patient whose short-term survival (48 - 72 hours) seems compromised,\n* Severe peripheral neuromyopathy,\n* Severe Acute Respiratory Distress Syndrome at the time of screening,\n* Hearing-impaired patients with hearing aids,\n* Pregnant or breastfeeding woman,\n* Patient under legal protection (persons deprived of their liberty or under guardianship).",{"count":55,"type":20},50,"INTERVENTIONAL",[58],"NA","The main aim of this study is to develop a new technique for the passive diagnosis of cognitive-motor dissociation, with the detection of motor intention in a comatose patient by analysing the EEG signal and in particular the ERD\u002FERS amplitudes in the motor cortex after stimulation of the median nerve.",[27,61,62],"Prognosis","Critical Care",[64,65,66,67,68],"Prognostication","Somatosensory evoked - potentials","Neurocritical care","Machine learning","Continuous EEG","2026-03-26",{"date":71,"type":38},"2026-04-02",{"date":73,"type":20},"2026-06-30",{"date":75,"type":20},"2028-06-30",{"name":77,"class":45},"University Hospital, Bordeaux"]