[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"confluent-and-reticulated-papillomatosis-carp\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:confluent-and-reticulated-papillomatosis-carp":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100628520","early-phase-1-topical-minocycline-for-carp-100628520",false,"NCT07462702","Topical Minocycline for CARP","Topical Minocycline Foam for Treatment of Confluent and Reticulated Papillomatosis (CARP)","Inclusion Criteria:\n\n* Age ≥ 9 years\n* Clinical diagnosis of CARP\n\nExclusion Criteria:\n\n* Current or recent (within 6 months) use of oral minocycline\n* Pregnancy or breastfeeding\n* History of intracranial hypertension, autoimmune disorder, liver\u002Fkidney disease\n* Immunocompromised status\n* Hypersensitivity to tetracyclines\n* Unstable medical condition\n* Inability or unwillingness to provide informed consent","ALL","9 Years",{"count":19,"type":20},35,"ESTIMATED","INTERVENTIONAL",[23],"EARLY_PHASE1","This proof-of-concept trial evaluates the efficacy, safety, and patient satisfaction of topical minocycline foam (AMZEEQ®) in patients aged 9 and older with confluent and reticulated papillomatosis (CARP). Participants will apply AMZEEQ® to one side of the body and a topical emollient to the other for 5 weeks, followed by an optional extension period. The study aims to assess whether topical minocycline is a well-tolerated and effective alternative to oral antibiotics.",[26],"Confluent and Reticulated Papillomatosis (CARP)",[28,29,30,31,32,33,34],"Topical Minocycline","Confluent and reticulated papillomatosis (CARP)","CARP","Confluent and reticulated papillomatosis","Minocycline","Tetracycline","Pruritus","NOT_YET_RECRUITING","2026-07-20",{"date":38,"type":39},"2026-07-21","ACTUAL",{"date":41,"type":20},"2026-09-15",{"date":43,"type":20},"2028-02",{"name":45,"class":46},"Medical University of South Carolina","OTHER"]