[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"congenital-hip-dysplasia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:congenital-hip-dysplasia":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,77],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100651224","manual-intervention-and-congenital-hip-dysplasia-in-infants-100651224",false,"NCT07756814","Manual Intervention and Congenital Hip Dysplasia in Infants","Exploring a Manual Intervention on the Coxal Bone in Infants With Congenital Hip Dysplasia: A Pilot Study","Inclusion Criteria:\n\n* Confirmed diagnosis of DDH, unilateral or bilateral\n* Graf score between IIa and III (moderate to severe DDH), as stage I may resolve spontaneously\n* Written parental authorization (or delegated parental representation) providing free and informed consent\n* Infant already receiving conservative orthopedic care with a Pavlik harness (the study tests a complementary intervention)\n* Parental availability for the study follow-up\n\nExclusion Criteria:\n\n* Presence of severe congenital anomalies\n* Neuromuscular or genetic diseases affecting muscle tone or bone growth\n* Cardiorespiratory conditions requiring constant monitoring\n* Fractures of the pelvis or lower limbs\n* Prematurity (birth before 37 weeks of gestation)\n* Medical contraindications to the proposed manual intervention\n* Ongoing physiotherapy or any manual therapy treatment outside the study framework\n* Growth retardation (staturo-ponderal), with or without suspected nutritional deficiencies\n* Infant showing distress or intolerance to physical handling during prior care\n* Simultaneous participation in another clinical study","ALL","1 Month","5 Months",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","Developmental dysplasia of the hip (DDH) is a developmental abnormality of the infant hip in which the acetabulum does not adequately cover the femoral head. Standard conservative treatment commonly includes a Pavlik harness. This exploratory randomized pilot study will assess whether a gentle manual intervention applied to the coxal bone, in addition to conventional orthopedic treatment, is associated with a greater change in ultrasound-measured femoral head coverage than conventional orthopedic treatment alone. Thirty infants aged 1 to 5 months with confirmed unilateral or bilateral DDH (Graf IIa to III) will be randomized to two parallel groups. The experimental group will receive one manual intervention session per week for three consecutive weeks in addition to conventional orthopedic treatment. The comparison group will receive conventional orthopedic treatment alone. Ultrasound assessments will be performed at baseline (T0) and after the intervention period (T1). In infants with bilateral DDH, both dysplastic hips will be evaluated at both time points and recorded separately. A secondary objective is to describe parental acceptability of the manual intervention and study procedures. As a pilot study, the project is intended to provide preliminary information on the direction and variability of the intervention effect, parental acceptability, and study feasibility to inform a future larger trial.",[27,28],"Developmental Dysplasia of the Hip (DDH)","Congenital Hip Dysplasia",[30,31,32,33,34],"Developmental dysplasia of the hip","Pilot study","manual therapy","coxal bone","infant","NOT_YET_RECRUITING","2026-08-05",{"date":38,"type":39},"2026-08-11","ACTUAL",{"date":41,"type":21},"2026-08",{"date":43,"type":21},"2027-09",{"name":45,"class":46},"Université de Sherbrooke","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":76},"100266486","the-medacta-international-sms-post-marketing-surveillance-study-100266486","NCT02748408","The Medacta International SMS Post-Marketing Surveillance Study","The Medacta SMS Femoral Stem Component. A Multi-National, Multi-Centre, Clinical Surveillance Study","Inclusion Criteria:\n\n* Individuals with a severely painful and\u002For disabling hip joint with osteoarthritis, traumatic arthritis or developmental dysplasia of the hip or avascular necrosis of the femoral head.\n* In order to take part in this study, all study participants must be between the ages of 18 and 75 years of age, at the time of surgery.\n* Scheduled for a primary total hip replacement.\n\nExclusion Criteria:\n\n* Active infection\n* Pregnancy\n* Mental illness where the known condition is likely to compromise the patient's ability to consent, affect the patient's assessment of their progress or complete the 10 year cycle of follow-up appointments and reviews\n* Grossly distorted anatomy (surgeon's discretion)\n* Osteomalacia where uncemented implant fixation is contraindicated\n* Active rheumatoid arthritis.\n* Osteoporosis\n* Metabolic disorders which may impair bone formation where uncemented implant fixation is contraindicated\n* Muscular atrophy or neuromuscular disease\n* Allergy to implant material\n* Any patient who cannot or will not provide informed consent for participation in the study\n* Those whose prospects for a recovery to independent mobility would be compromised by known coexistent, medical problems","18 Years","75 Years",{"count":57,"type":21},550,"OBSERVATIONAL","This is a Post-Marketing Surveillance of SMS femoral stem prosthesis.",[61,62,63,28,64],"Arthrosis","Traumatic Arthritis","Rheumatoid Polyarthritis","Avascular Necrosis of the Femoral Head","RECRUITING","2025-09-23",{"date":68,"type":39},"2025-09-29",{"date":70,"type":4},"2015-07",{"date":72,"type":21},"2032-07",{"name":74,"class":75},"Medacta International SA","INDUSTRY",4,{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":11,"sex":16,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":89,"conditions":90,"keywords":102,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":116},"100371538","global-hip-dysplasia-registry-100371538","NCT04117685","Global Hip Dysplasia Registry","A Prospective, Global Hip Dysplasia Registry with Follow-up to Skeletal Maturity: an Analysis of Risk Factors, Screening Practices and Treatment Outcomes","GHDR","Inclusion Criteria:\n\n* Between the ages of 0 and 10 years at time of initial diagnosis\n* Referred for DDH screening due to specific risk factors OR diagnosed with DDH\n* Diagnosis confirmed with appropriate ultrasonographic or radiographic imaging\n\nExclusion Criteria:\n\n* Known or suspected neuromuscular, collagen, chromosomal or lower extremity congenital anomalies\n* Teratologic hip dislocation (syndromic-associated dislocations)\n* Over 10 years of age at initial diagnosis\n* Received prior treatment for DDH without appropriate imaging or documentation","1 Minute","10 Years",{"count":88,"type":21},5000,"Developmental dysplasia of the hip (DDH) is the most common hip condition affecting infants and children. DDH represents a spectrum of issues affecting the hip joint - a \"ball-and-socket\" joint. When the femoral head (the \"ball) is seated properly in the acetabulum (the \"socket\"), the hip is stable and can develop normally. However, when the femoral head is not well-seated, the hip can become unstable or dislocate. This instability or dislocation of the femoral head prevents the hip joint from developing normally during infancy and early childhood. If left undetected or untreated, it can lead to debilitating complications later in life.\n\nDevelopment of a comprehensive, prospective international registry for all infants and children with DDH will provide the potential to impact all infants born, not only in British Columbia, but around the world. The purpose of this initiative is to identify best practices and standardize treatment and management strategies in order to optimize clinical and functional outcomes for patients with DDH. This registry includes targeted specific outcomes that will be investigated, in addition to the general collection of data on all patients diagnosed with any form of DDH up to the age of 10 years.",[91,92,93,94,95,28,96,97,98,99,100,101],"Hip Dislocation, Congenital","Hip Dysplasia, Congenital, Nonsyndromic","Congenital Dysplasia of the Hip","Congenital Hip Dislocation","Congenital Hip Displacement","Dislocation of Hip, Congenital","Dislocation, Congenital Hip","Displacement, Congenital Hip","Dysplasia, Congenital Hip","Hip Displacement, Congenital","Hip, Dislocation Of, Congenital",[103,104,105,106],"hip dysplasia","ddh","developmental dysplasia of the hip","congenital hip dysplasia","2024-11-13",{"date":109,"type":39},"2024-11-18",{"date":111,"type":39},"2016-09-01",{"date":113,"type":21},"2028-12-31",{"name":115,"class":46},"University of British Columbia",1]