[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"congenital-peumonia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:congenital-peumonia":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":4,"maxAge":4,"enrollmentInfo":16,"targetDuration":4,"studyType":19,"phases":20,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100658259","effect-of-melatonin-on-pulmonary-hypertension-in-full-term-neonates-100658259",false,"NCT07850934","Effect of Melatonin on Pulmonary Hypertension in Full Term Neonates","Inclusion criteria :\n\n* Term neonates with gestational age ≥ 37 weeks.\n* Mean Pulmonary artery pressure greater than 25mmHg with clinical manifestations as tachypnea, tachycardia, hypoxemia and hypotension\n\nExclusion criteria :\n\n* Congenital methemoglobinemia.\n* Major congenital cardiac anomalies especially duct dependent systemic circulation.\n* Bleeding tendency.\n* Patients on other pulmonary vasodilators","ALL",{"count":17,"type":18},52,"ESTIMATED","INTERVENTIONAL",[21],"NA","The aim of the study\n\n1. To evaluate safety and efficacy of melatonin as an adjuvant therapy to inhaled nitric oxide generated by NO generator in the treatment of pulmonary hypertension in full term neonates.\n2. To assess the effect of inhaled nitric oxide and melatonin on cerebral perfusion.",[24,25,26],"Congenital Peumonia","Persistent Pulmonary Hypertension of Newborn","Congenital Diaphragmatic Hernia",[28,29],"Nitric oxide generator","Melatonin","RECRUITING","2026-09-28",{"date":33,"type":34},"2026-09-30","ACTUAL",{"date":36,"type":34},"2025-07-01",{"date":38,"type":18},"2026-12-01",{"name":40,"class":41},"Ain Shams University","OTHER"]