[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"coronary-angiography-cag\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:coronary-angiography-cag":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,48,84,113,136],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100652055","ccta-based-vs-cag-based-cabg-a-multicenter-pragmatic-non-inferiority-trial-100652055",false,"NCT07769008","CCTA-Based vs CAG-Based CABG: A Multicenter Pragmatic Non-Inferiority Trial","Coronary Computed Tomography Angiography-Based Versus Coronary Angiography-Based Coronary Artery Bypass Grafting: A Multicenter Pragmatic Non-Inferiority Randomized Controlled Trial","CtaCAB","Inclusion Criteria:\n\n* Referred to CABG treatment\n\nExclusion Criteria:\n\n* Under the age of 18 years\n* Unable to provide informed consent\n* Emergency CABG\n* Redo-CABG\n* Prior PCI with coronary stent implantation\n* Cardiogenic shock\n* Unable to undergo CAG or CCTA examination or deemed unsuitable by the investigator, such as:\n\nKnown allergy to iodinated contrast media; Active hyperthyroidism or uncontrolled thyroid disease; Estimated glomerular filtration rate (eGFR) \\\u003C 30 mL\u002Fmin\u002F1.73 m²; Atrial fibrillation with rapid ventricular response or severe arrhythmias not amenable to rate control;\n\n* Pregnancy, lactation, or childbearing potential without effective contraception in female participants\n* Concurrent participation in another interventional trial","ALL","18 Years",{"count":20,"type":21},826,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to find out if using a non-invasive heart scan (called coronary computed tomography angiography, or CCTA) to plan coronary artery bypass grafting (CABG) works as well as the standard invasive approach (called coronary angiography, or CAG) for people with blocked heart arteries.\n\nThe main questions it aims to answer are:\n\nDo people who have surgery planned with the non-invasive heart scan have similar health outcomes at 1 year as those who have surgery planned with the standard invasive approach? How does the non-invasive approach compare in terms of heart attacks, strokes, unplanned repeat procedures, and longer hospital stays? Researchers will compare two groups of participants. One group will have their surgery planned using only the CCTA . The other group will have their surgery planned using only the CAG. Both groups will undergo the CABG per local protocol.\n\nParticipants will:\n\nBe randomly assigned (like flipping a coin) to one of the two planning approaches Undergo CABG as scheduled Return for follow-up visits at sugery days, 7 days, 1 month, 6 months, and 1 year after surgery Have a follow-up CCTA scan at 7 days and 1 year to check if the new bypass grafts are working well",[27,28,29,30],"Coronary Artery Disease","Coronary Artery Bypass Grafting","Coronary Computed Tomography Angiography","Coronary Angiography (CAG)",[32,33,34,35],"Major Adverse Cardiovascular Events (MACE)","Coronary Artery Bypass Grafting (CABG)","Coronary Computed Tomography Angiography(CCTA)","Coronary Angiography(CAG)","RECRUITING","2026-08-17",{"date":39,"type":40},"2026-08-19","ACTUAL",{"date":37,"type":40},{"date":43,"type":21},"2029-08",{"name":45,"class":46},"Ruijin Hospital","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":70,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":47},"100647502","serpentine-vs-traditional-hydrophilic-guidewire-tracking-in-complex-radial-anatomy-100647502","NCT07707427","Serpentine vs Traditional Hydrophilic Guidewire Tracking in Complex Radial Anatomy","Comparison of the \"Serpentine\" Technique Versus Hydrophilic Guidewire 0,035'' for Navigating Radial and Brachial Artery Loops, Tortuosity and Sharp Angulation During Transradial Access.","S-TRACK","Inclusion Criteria:\n\n* Age ≥18 years\n* Feasibility of TRA\n* Indication for coronary angiography\n* Angiographic documentation of radial or brachial artery loop\u002Ftortuosity\n* Written informed consent\n\nExclusion Criteria:\n\n* STEMI - high risk NSTEMI presentation\n* Hemodynamic instability\n* Anatomical contraindications (e.g., arteriovenous fistula)\n* Significant calcification of the radial or brachial artery on angiographic evaluation.",{"count":57,"type":21},204,[24],"Coronary angiography and angioplasty are commonly performed through the radial artery. In some patients, anatomical variations of the radial and brachial arteries, such as loops, increased tortuosity or sharp angulations may pose challenges to equipment advancement.\n\nBoth the hydrophilic guidewire 0,035'' approach and the \"Serpentine\" technique have been described in the literature as techniques for overcoming radial anatomical challenges, with the hydrophilic guidewire approach being the more commonly used method.\n\nIn practical terms, both techniques involve the use of the same standard materials, with differences relating mainly to operator handling and technical manipulation. This study does not introduce any experimental device, material, or treatment; instead, it aims to compare the established approach using a 0.035'' hydrophilic guidewire with the emerging \" Serpentine\" technique with respect to effectiveness, procedural time, and safety.",[61,30,62,63,64,65,66,67,68,69],"Transradial Access(TRA)","Percutaneous Coronary Intervention (PCI)","Radial Artery Loop","Radial Artery Tortuosity","Serpentine Technique","Hydrophilic Guidewire","Complex Radial Anatomy","Vascular Complications","Coronary Catheterization",[71,72,30,62,73,74,65,66,67,68],"Coronary catheterization","Transradial access(TRA)","Radial artery loop","Radial artery tortuosity","2026-07-15",{"date":77,"type":40},"2026-07-16",{"date":79,"type":40},"2026-05-14",{"date":81,"type":21},"2029-11",{"name":83,"class":46},"University Hospital of Patras",{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":4,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":91,"enrollmentInfo":92,"targetDuration":4,"studyType":22,"phases":94,"briefSummary":95,"conditions":96,"keywords":97,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":47},"100590628","effect-of-virtual-reality-glasses-on-stress-muscle-tension-and-physiological-parameters-before-angiography-100590628","NCT06969885","Effect of Virtual Reality Glasses on Stress, Muscle Tension, and Physiological Parameters Before Angiography","The Effect of Virtual Reality Glasses Applied Before Coronary Angiography on Patients' Stress Levels, Muscle Tension, and Certain Physiological Parameters","Inclusion Criteria: - 18-65 years of age,\n\n* Scheduled to undergo CAG,\n* American Society of Anesthesiologists (ASA) score I or II,\n* Turkish-speaking patients will be included.\n\nExclusion Criteria: Patients with nausea,\n\n* with dizziness,\n* with headache,\n* with any known psychiatric disease and mental perception problem,\n* pregnant,\n* with a history of epilepsy,\n* with vision, hearing and perception problems,\n* with closed space phobia,\n* with a history of dizziness, nausea, etc. due to previous virtual reality use will not be included in the study.","65 Years",{"count":93,"type":21},60,[24],"Today, cardiovascular diseases are the leading cause of morbidity and mortality worldwide. Coronary angiography (CAG), a commonly used invasive procedure for diagnosing coronary artery disease, may trigger fear, stress, and anxiety in patients due to its invasive nature, lack of information, uncertainty, and the possibility of receiving a life-threatening diagnosis.These emotional responses activate stress mechanisms, leading to catecholamine release, increased heart rate, blood pressure, respiration, sweating, and muscle tension. Elevated stress can also cause lactic acid accumulation, increased oxygen demand, and muscular contraction, potentially resulting in coronary artery spasms or arrhythmias, and increasing procedural risks. Therefore, reducing stress before CAG is crucial to improving procedural outcomes and patient recovery.\n\nTo address preoperative anxiety and stress, both pharmacologic and non-pharmacologic interventions are used. Among the non-pharmacologic options, virtual reality (VR) has emerged as an effective method to distract and calm patients, reducing anxiety, stress, and pain. Studies in various patient populations suggest VR glasses can be beneficial in managing psychological distress. However, no study has been found in the literature evaluating the effect of VR on stress-induced muscle tension in patients undergoing CAG. This gap highlights the potential contribution of this study to current knowledge.\n\nThis study aims to investigate the effect of using VR glasses before coronary angiography on patients' stress levels, muscle tension, and selected physiological parameters.",[30],[98,99,100,101,102],"Coronary Angiography","Virtual Reality Glasses","Stress","Muscle Tension","Physiological Parameters","NOT_YET_RECRUITING","2025-05-13",{"date":106,"type":40},"2025-05-14",{"date":108,"type":21},"2025-07-01",{"date":110,"type":21},"2025-12-30",{"name":112,"class":46},"Yuksek Ihtisas University",{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":4,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":120,"targetDuration":4,"studyType":22,"phases":121,"briefSummary":122,"conditions":123,"keywords":124,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":132,"leadSponsor":134,"locationsCount":47},"100576028","effect-of-foot-massage-after-coronary-angography-on-back-pan-and-vtal-sgns-100576028","NCT06779955","Effect of Foot Massage After Coronary Angıography on Back Paın and Vıtal Sıgns","The Research Was Planned As a Randomized Controlled Experimental Study to Evaluate the Effects of Foot Massage on Back Pain and Vital Signs in Patients Undergoing Coronary Angiography.","Inclusion Criteria:\n\n* Literate\n* Over 18 years of age,\n* Transfemoral CAG,\n* No vision or hearing problems,\n* Dorsal pedal and posterior tibial pulses are normal,\n* No back pain in the last week before CAG,\n\nExclusion Criteria:\n\n* No physiological or hemodynamic instability during and after CAG,\n* Sensory disorders that impair the perception of back pain (paraplegia)\n* Active bleeding at the site of cardiac dysrhythmia or catheter insertion,\n* Known hemorrhagic disorders,\n* History of spinal surgery or herniated disc in the lower back,\n* Inflammation or infection in the leg or sole,\n* Serious health problems in the feet,\n* Not using opioid agents, tranquilizers or anesthetics before, during and 4 hours after CAG",{"count":93,"type":21},[24],"The aim of the study was to evaluate the effect of foot massage on patients' back pain and vital signs after coronary angiography. It is important for the transfer of nonpharmacological methods to clinical applications",[30],[125,126,127],"CAD","NURSİNG","ayak masajı","2025-01-15",{"date":130,"type":40},"2025-01-17",{"date":128,"type":21},{"date":133,"type":21},"2025-10-15",{"name":135,"class":46},"ayşenur kahveci",{"id":137,"slug":138,"hasResults":11,"nctId":139,"briefTitle":140,"officialTitle":141,"acronym":4,"eligibilityCriteria":142,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":143,"targetDuration":4,"studyType":22,"phases":145,"briefSummary":146,"conditions":147,"keywords":148,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":153,"completionDateStruct":154,"leadSponsor":156,"locationsCount":4},"100571870","effects-of-white-noise-and-earplugs-on-patients-physiological-parameters-pain-comfort-and-procedure-satisfaction-100571870","NCT06725875","Effects of White Noise and Earplugs on Patients' Physiological Parameters, Pain, Comfort and Procedure Satisfaction","Effects of White Noise and Earplugs Applied During Coronary Angiography on Patients' Physiological Parameters, Pain, Comfort and Procedure Satisfaction: A Randomized Controlled Experimental Study","Inclusion Criteria:\n\n* Patients who do not have vision, hearing, speech or comprehension problems, are 18 years of age or older, are open to communication and cooperation, do not have a psychiatric disease and agree to participate in the study will be included in the study.\n\nExclusion Criteria:\n\n* Those with cognitive impairment or any auditory problems that may affect the test results, or those using psychoactive drugs will not be included in the study.",{"count":144,"type":21},90,[24],"Coronary artery disease (CAD) is the leading cause of mortality and morbidity worldwide. Coronary Angiography (CAG) is an invasive method used in the diagnosis and treatment of CAD. Invasive methods such as coronary angiography cause pain. The sympathetic nervous system is stimulated and vital functions can be affected by the increased stress level of the pain experienced. In the angiography laboratory, patients are awake, aware of everything, and can easily hear the sounds of the monitor and the comments and conversations of the healthcare team. This auditory exposure can further trigger the patient's fear and anxiety and increase their pain. Increased anxiety can lead to an increase in the intensity of perceived pain and a decrease in pain tolerance. In addition to anxiety, catastrophizing such as fear of death can also be a means for disability and complications. In the literature, it is recommended to use nonpharmacological methods together with pharmacological treatment to increase pain tolerance and improve patient comfort and satisfaction in patients affected by invasive procedures. Nonpharmacological methods, unlike pharmacological agents, do not cause any harm to patients. It can help to keep physiological parameters such as blood pressure, respiration and pulse rate at normal levels and to increase comfort and satisfaction with the procedure. Sound therapy, which is a non-pharmacological method, turns the person's attention from negative stimuli to positive and hopeful feelings and can reduce stress, anxiety and pain.\n\nNon-pharmacological methods such as white noise therapy and using earplugs that prevent sound permeability can be used to distract the patient's attention from the source of stress and focus on other thoughts. It is suggested that patients exposed to 50 to 55 dB white noise experience pain relief and have an effect on heart rate and oxygen saturation (12). As a result of our literature review, no studies were found where white noise was applied during coronary angiography. This situation reveals the originality of our study. With white noise, the patient can be isolated from ambient sounds during the procedure and the stress experienced can be controlled, the increase in pain intensity and decrease in tolerance that may occur due to stress can be controlled, and the patient's comfort and satisfaction level during the procedure can be increased. We think that the patient's compliance during the procedure can be increased.\n\nThe noise in the units affects the anxiety levels of the patients. The literature supports that the use of earplugs increases the comfort of the patient. In the study investigating the effect of auditory interventions on pain and comfort, it was determined that the pain level and heart rate were lower and the comfort level was higher in patients using earplugs compared to the control group. More evidence is needed on the effect of earplugs on physiological parameters, pain, comfort and procedure satisfaction of the patients by applying them to different patient groups. As a result of our literature review, no study was found where earplugs were applied during the coronary angiography procedure. This situation reveals another originality of our study.\n\nThe nurse involved in every step of coronary angiography aims to ensure that the patient benefits from the procedure to a high extent and to increase the quality of the procedure by integrating innovative methods. Nursing practices that increase the quality of the procedure are included in national and international nursing care guidelines. Therefore, in order to implement quality nursing care, it is necessary to increase the number of randomized controlled experimental studies and to increase the level of evidence. The fact that our study was a pre-test post-test randomized controlled double-blind study will increase the level of evidence in this regard. This situation reveals another originality of our study.\n\nThis study will use a randomized pre-test and post-test control group experimental design. It is planned that a total of 150 patients will participate in the study; 50 in the white noise group, 50 in the earplug group, and 50 in the control group. Data of the study will be collected via ''Personal information form, Numeric Pain Scale (NPS), Numeric Satisfaction Scale (NMS), Numeric Comfort Scale (NKS)''. A web-based randomization system will be used to determine the groups in the study. Pulse rate, respiratory rate, systolic blood pressure (SBP), diastolic blood pressure (DBP) and oxygen saturation values (SpO2) will be evaluated before, during, and after the procedure. Pain, satisfaction, and comfort levels will be evaluated at the end of the procedure. Interventions will be performed by the researcher and the patients will be observed throughout the intervention.",[30],[149],"White noise, earplug, coronary angiography, nurse, pain, comfort","2024-12-09",{"date":152,"type":40},"2024-12-10",{"date":152,"type":21},{"date":155,"type":21},"2025-02-25",{"name":157,"class":46},"Di̇lek Soylu"]