[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"coronary-angiography\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:coronary-angiography":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,42,73,101,138],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100652175","hemostatc-pad-and-sandbag-100652175",false,"NCT07771127","HEMOSTATİC PAD AND SANDBAG","Comparison of Factors Related to Bleeding, Pain, Comfort Level, and Sleep Quality in Patients Undergoing Femoral Coronary Angiography Using a Chitosan-Containing Hemostatic Pad Versus a Sandbag","Inclusion Criteria:\n\n* Patients aged 18 years and older scheduled for femoral coronary angiography (CAG) and\u002For percutaneous coronary intervention (PCI)\n* Patients undergoing a single femoral arterial access procedure\n* Patients with sheath size typically 5-Fr, 6-Fr, or 7-Fr\n* Patients who are conscious, alert, and able to communicate\n* Patients who voluntarily agreed to participate in the study\n\nExclusion Criteria:\n\n* Patients with known allergy to shellfish or chitosan Patients using antihistamines, psychotropic medications, or sleep medications Patients with systolic and\u002For diastolic blood pressure above 150\u002F100 mmHg Patients with known bleeding disorders (e.g., hemophilia) or active bleeding Patients with severe renal or hepatic failure Pregnant or breastfeeding patients Patients with a history of malignancy","ALL","18 Years",{"count":19,"type":20},480,"ESTIMATED","INTERVENTIONAL",[23],"NA","The aim of this study is to compare bleeding outcomes, pain, comfort levels, sleep quality, and associated factors among patients receiving a chitosan-based hemostatic pad versus a sandbag following femoral coronary angiography (CAG) and percutaneous coronary intervention (PCI).\n\nFemoral coronary angiography (CAG) and percutaneous coronary intervention (PCI) are widely performed procedures for the diagnosis and treatment of coronary artery disease (CAD), which remains the leading cause of mortality worldwide (Batmaz \\& Cengiz, 2023; Wardiyana et al., 2024). Hemostasis following CAG and PCI is critical for preventing life-threatening complications, ensuring procedural success, and facilitating recovery. Vascular complications at the femoral arterial puncture site are among the most common adverse events associated with these procedures (Chen et al., 2021). Inadequate hemostasis may result in serious complications such as pseudoaneurysm, arteriovenous fistula, and retroperitoneal hemorrhage, all of which may pose significant risks to patient safety (Sauer et al., 2016). Effective bleeding control is particularly important in patients receiving intensive anticoagulant therapy.\n\nFollowing manual compression, sandbag application is commonly used to maintain hemostasis at the femoral access site. Typically, a sandbag weighing between 2.3 and 5 kilograms is placed over the puncture site, requiring patients to remain in a supine position with restricted mobility for approximately four to six hours (Batmaz \\& Cengiz, 2023). Although prolonged bed rest and sandbag application contribute to hemostasis, they may also lead to adverse patient experiences, including pain, discomfort, urinary retention, restlessness, and impaired sleep quality (Batmaz \\& Cengiz, 2023).\n\nAdvances in medical technology have led to the development of hemostatic devices designed to rapidly control bleeding independently of the body's natural coagulation mechanisms. Among these, chitosan-based hemostatic pads, derived from crustacean shells, have attracted increasing attention. Due to their positive electrical charge, chitosan molecules attract negatively charged erythrocytes and platelets, facilitating the rapid formation of a mechanical barrier and clot within seconds (Arbel et al., 2010; Kılıç et al., 2024). Previous studies have demonstrated that chitosan-based pads may reduce manual compression time and vascular complications such as ecchymosis and hematoma (Ginanjar et al., 2018; Kılıç et al., 2024; Qian et al., 2024). Furthermore, they have been associated with improved patient comfort, earlier mobilization, and shorter hospital stays (Kılıç et al., 2024; Liu, 2025).\n\nThe responsibilities of nurses following CAG and PCI extend beyond bleeding control and include comprehensive monitoring of vital signs, early detection of complications, and the promotion of patient comfort and well-being (Batmaz \\& Cengiz, 2023; Rodrigues et al., 2024). While existing studies have primarily focused on the effectiveness of chitosan-based pads in reducing hematoma formation (Bektaş et al., 2017), evidence regarding their effects on broader patient-centered outcomes remains limited. Therefore, this study seeks to provide a comprehensive evaluation of chitosan-based hemostatic pads and conventional sandbag application with respect to bleeding outcomes, pain, patient comfort, and sleep quality.\n\nAccordingly, the present study aims to compare bleeding, pain, comfort levels, sleep quality, and related factors among patients undergoing femoral CAG and PCI who receive either a chitosan-based hemostatic pad or a sandbag for post-procedural hemostasis.\n\nThe sample size was calculated using a power analysis based on an effect size of 0.40, a significance level of 5% (α = 0.05), and a statistical power of 80% (1-β = 0.80). According to the analysis, a total of 480 participants will be recruited, including 240 patients in the chitosan-based hemostatic pad group and 240 patients in the sandbag group.",[26,27,28],"Coronary Artery Disease","Coronary Angiography","Vascular Access Site Complications","RECRUITING","2026-08-13",{"date":32,"type":33},"2026-08-18","ACTUAL",{"date":35,"type":33},"2026-06-10",{"date":37,"type":20},"2026-12-30",{"name":39,"class":40},"Uludag University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":21,"phases":51,"briefSummary":52,"conditions":53,"keywords":58,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":41},"100584513","timing-of-anticoagulant-administration-during-radial-access-percutaneous-coronary-intervention-the-hera-pci-study-heparin-early-for-radial-access-percutaneous-coronary-intervention-100584513","NCT06890312","Timing of Anticoagulant Administration During Radial Access Percutaneous Coronary Intervention: the HERA-PCI Study (Heparin Early for Radial Access Percutaneous Coronary Intervention)","HERA-PCI","Inclusion Criteria:\n\n* Patients having 18 years old or older, regardless of gender, undergoing percutaneous radial coronary intervention\n* Subject affiliated to a social protection health insurance\n* Subject able to understand the objectives and risks of the research and to provide dated and signed consent\n* Subject who has been informed of the results of the preliminary medical examination\n\nExclusion Criteria:\n\n* Contraindication to the use of heparin (history of heparin-induced thrombocytopenia)\n* Very high bleeding risk defined by recent bleeding (\\\u003C6 months) of type 3 of the BARC classification\n* Subject in an exclusion period (determined by a previous or ongoing study)\n* Inability to give the subject enlightened information (subject in an emergency situation, difficulties in understanding the subject, etc.)\n* Subject under safeguard of justice\n* Subject under guardianship or curatorship\n* Pregnancy\n* Breastfeeding\n* Patient on anticoagulant treatment: anti-vitamin K, direct oral anticoagulants (DOACs).",{"count":50,"type":20},550,[23],"While the reduced hemorrhagic risk of radial access for percutaneous coronary intervention compared to femoral access is well-established, its main complication remains radial artery occlusion, which can occur in up to 30% of patients. Anticoagulation is the primary preventive measure recommended in clinical practice to reduce the risk of this complication, typically involving heparin injection during the procedure in most centers. However, data on the effect of the timing of heparin injection are limited. The investigators hypothesize that injection of heparin before sheath insertion may reduce the rate of radial artery occlusion compared with injection after sheath insertion.",[27,54,55,56,57],"Percutaneous Coronary Intervention","Radial Artery Occlusion","Bleeding","Anticoagulation",[59,60,61,62,63],"Anticoagulant injection timing","Percutaneous coronary intervention","Coronary angiography","Radial artery occlusion prevention","Bleeding events","2026-05-20",{"date":66,"type":33},"2026-05-26",{"date":68,"type":33},"2025-06-05",{"date":70,"type":20},"2028-01",{"name":72,"class":40},"University Hospital, Strasbourg, France",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":82,"phases":4,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":91,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":41},"100614106","incidental-findings-on-coronary-computed-tomography-angiography-100614106","NCT07275281","Incidental Findings on Coronary Computed Tomography Angiography","Incidental Noncardiac Findings on Coronary Computed Tomography Angiography","Inclusion Criteria:\n\n* Adult patients ho underwent CCTA\n\nExclusion Criteria:\n\n* None",{"count":81,"type":20},2000,"OBSERVATIONAL","Coronary CT angiography (CCTA) is increasingly used for ischemic heart disease diagnosis. The rising number of CCTA tests has led to a significant increase in the number of finding unexpected incidental extracardiac diseases.",[85,27,86],"Computed Tomography","Incidental Findings",[88,89,90],"Coronary artery disease","computed tomography","indidental findings","NOT_YET_RECRUITING","2025-12-22",{"date":94,"type":33},"2025-12-30",{"date":96,"type":20},"2026-01-02",{"date":98,"type":20},"2027-02-28",{"name":100,"class":40},"Jordan Collaborating Cardiology Group",{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":105,"acronym":106,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":21,"phases":110,"briefSummary":113,"conditions":114,"keywords":118,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":137},"100437910","phase-2-remote-ischemic-preconditioning-for-renal-and-cardiac-protection-in-congestive-heart-failure-rich-trial-100437910","NCT04982419","Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial","RICH","Inclusion Criteria:\n\n* Age 18 years\n* Diagnosis of heart failure with reduced LVEF \\\u003C50%\n* Pre-procedure intravenous normal saline fluid restriction status\n* Society for Cardiovascular Angiography and Interventions (SCAI) AKI risk score (\\>1%)\n* Referral for coronary angiogram and\u002For PCI\n* Suspected stable coronary artery disease or acute coronary syndrome\n\nExclusion Criteria:\n\n* Inability to give informed consent\n* Unstable BP (SBP \\> 200 or \\\u003C80 mmHg) at the time of enrolment\n* Upper limb peripheral arterial disease\n* Unavailability of at least one arm for RIPC\u002FSham-RIPC application\n* Kidney transplant\n* Renal disease requiring dialysis\n* Prior exposure to contrast media within 72hrs preceding coronary angiography\n* Pregnancy\n* Prisoner",{"count":109,"type":20},240,[111,112],"PHASE2","PHASE3","This is a prospective, double-blind, sham-controlled, multicenter, randomized clinical trial is to study the effects of remote ischemic preconditioning on contrast-associated acute kidney injury, functional capacity, and major adverse kidney events in in patients with congestive heart failure undergoing cardiac catheterization and\u002For percutaneous coronary intervention.",[115,116,117,27,54],"Acute Kidney Injury","Heart Failure","Contrast Induced Nephropathy",[119,120,121,61,60,88,122,123,124,125,126],"Contrast-induced acute kidney injury","Congestive heart failure","Contrast induced nephropathy","Remote ischemic conditioning","acute coronary syndrome","Acute kidney injury","Major adverse kidney events","Ischemic preconditioning","2025-12-09",{"date":129,"type":33},"2025-12-15",{"date":131,"type":33},"2021-11-01",{"date":133,"type":20},"2029-03-31",{"name":135,"class":136},"VA Office of Research and Development","FED",3,{"id":139,"slug":140,"hasResults":11,"nctId":141,"briefTitle":142,"officialTitle":143,"acronym":4,"eligibilityCriteria":144,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":145,"enrollmentInfo":146,"targetDuration":4,"studyType":21,"phases":148,"briefSummary":149,"conditions":150,"keywords":4,"overallStatus":91,"whyStopped":4,"lastUpdateSubmitDate":153,"lastUpdatePostDateStruct":154,"startDateStruct":156,"completionDateStruct":158,"leadSponsor":160,"locationsCount":4},"100560094","the-effect-of-progressive-relaxation-exercise-performed-before-coronary-angiography-100560094","NCT06572670","The Effect of Progressive Relaxation Exercise Performed Before Coronary Angiography","The Effect of Progressive Relaxation Exercise Performed Before Coronary Angiography on Anxiety, Comfort, Pain and Physiological Parameters","Inclusion Criteria:\n\n* Patients who can speak and understand Turkish,\n* Are over 18 years old,\n* Have space and time orientation,\n* Will undergo coronary angiography for the first time,\n* Do not have any psychiatric illness,\n* Do not have vision or hearing problems,\n* Volunteer to participate in the study will be included.\n\nExclusion Criteria:\n\n* Patients who experience any pain or have chronic pain before coronary angiography,\n* Patients who use antihistamines and psychiatric medications,\n* Patients who do not volunteer to participate in the study,\n* Patients who have undergone orthopedic surgery or have any medically diagnosed health problems (orthopedic, neurological, psychological) that prevent relaxation exercises,\n* Patients who have taken sedatives or painkillers up to 5 hours before coronary angiography will not be included in the study.","75 Years",{"count":147,"type":20},70,[23],"This study was planned to examine the effects of progressive relaxation exercise on anxiety, comfort, pain and physiological parameters in patients undergoing coronary angiography. The data of the study will be collected using the Descriptive Characteristics Questionnaire Form, State and Trait Anxiety Inventory, Perianesthesia Comfort Questionnaire, Visual Analog Scale (VAS), Vital Signs Follow-up Form, Complication Follow-up Form and Progressive Relaxation Exercise Application Guidelines.",[27,151,152],"Progressive Relaxation Exercise","Nursing","2024-08-23",{"date":155,"type":33},"2024-08-27",{"date":157,"type":20},"2024-09-15",{"date":159,"type":20},"2025-02-15",{"name":161,"class":40},"TC Erciyes University"]