[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"crowding-of-teeth\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:crowding-of-teeth":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100650806","effect-of-different-adhesive-systems-on-white-spot-lesions-during-fixed-orthodontic-treatment-100650806",false,"NCT07753512","Effect of Different Adhesive Systems on White Spot Lesions During Fixed Orthodontic Treatment","Effect of Different Adhesive Systems on White Spot Lesions During Fixed Orthodontic Treatment: A Split Mouth Randomized Controlled Trial","Inclusion Criteria:\n\n* healthy patients 12-30 yrs\n* patients undergoing fixed appliance treatment with full mouth bonding\n* presence of at least 7 accessible teeth\n* no cavitated lesion at time of bond up\n\nExclusion Criteria:\n\n* patients with chronic or systematic diseases\n* patients with fluorosis or enamel defects\n* presence of fixed prosthesis\n* patients on medications which could alter salivary flow\n* patients with history of salivary gland disease",true,"ALL","12 Years","30 Years",{"count":21,"type":22},34,"ESTIMATED","INTERVENTIONAL",[25],"NA","The primary goal of this study is to compare the number of white spot lesions during fixed appliance therapy between self-etch and one-step bonding systems.",[28,29],"Malaligned Teeth","Crowding of Teeth",[31,32],"white spot lesions","orthodontic adhesives","NOT_YET_RECRUITING","2026-08-06",{"date":36,"type":37},"2026-08-10","ACTUAL",{"date":39,"type":22},"2027-01-15",{"date":41,"type":22},"2028-06-15",{"name":43,"class":44},"Foundation University Islamabad","OTHER"]