[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"deconditioning\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:deconditioning":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100647579","exercise-to-improve-outcomes-in-pancreatic-cancer-100647579",false,"NCT07710495","Exercise to Improve Outcomes in Pancreatic Cancer","Exercise-Based Pre-, Peri- and Post-Surgery Intervention to Improve Clinical and Translational Outcomes in Patients Undergoing Whipple's Procedure: A Feasibility Study.","ExO-PanC","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Planned to undergo upfront pancreatoduodenectomy (Whipple's procedure) for a suspected malignant periampullary mass.\n* Able and willing to provide written informed consent.\n\nExclusion Criteria:\n\n* \\\u003C18 years age\n* Cardiopulmonary exercise test (CPET) contraindications\n* Physical inability to perform CPET or undertake the program.\n* Lacking the capacity to consent\n* Unable to understand instructions in English\n* Not scheduled for surgery\n* A new diagnosis of Type 1 or Type 3c diabetes requiring management with insulin prescription will be excluded from the study.","ALL","18 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","Pancreatic cancer surgery (Whipple's procedure) is a major operation that can lead to reduced physical fitness, delayed recovery, and difficulty starting chemotherapy after surgery. Exercise before and after surgery may help improve recovery, but it is not known whether a personalised exercise programme delivered throughout the surgical pathway is practical or acceptable for patients.\n\nThe Exercise to Improve Outcomes in Pancreatic Cancer (ExO-PanC) study is a single-arm feasibility study that will recruit adults with suspected pancreatic ductal adenocarcinoma who are scheduled to undergo Whipple's procedure. Participants will receive an individualised exercise programme before surgery, during their hospital stay, and after discharge until the start of adjuvant chemotherapy. The programme will include aerobic exercise and resistance training prescribed according to each participant's fitness level.\n\nThe primary objective is to determine whether this exercise programme is feasible by assessing recruitment, participant adherence, compliance with the prescribed exercise programme, and retention. Secondary exploratory objectives include evaluating surgical complications, initiation of adjuvant chemotherapy, physical fitness, quality of life, nutritional status, and blood, stool, and tumour biomarkers associated with clinical outcomes. Findings from this feasibility study will inform the design of a future multicentre randomised controlled trial evaluating the effectiveness of the ExO-PanC programme.",[27,28],"Pancreas Adenocarcinoma (MSI-H)","Deconditioning",[30,31,32],"prehabilitation","rehabilitation","exercise","RECRUITING","2026-07-13",{"date":36,"type":37},"2026-07-17","ACTUAL",{"date":39,"type":21},"2026-07-06",{"date":41,"type":21},"2030-06-01",{"name":43,"class":44},"University of Surrey","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":4},"100568648","ai-assisted-telerehabilitation-system-atlas-for-post-discharge-continuation-of-rehabilitative-care-100568648","NCT06683963","AI-Assisted TelerehabiLitAtion System (ATLAS) for Post-discharge Continuation of Rehabilitative Care","Inclusion Criteria:\n\n1. Rehabilitation Diagnostic Group (RDG): Total Knee Replacement \u002F Deconditioning\n2. Age 60 and above\n3. Speak English\u002FMandarin\n4. Able to follow instructions, no cognitive impairment\n5. No MDRO (MultiDrug Resistant Organism)\n6. Suitable and able to wear motion sensor on upper and lower limbs\n7. Suitable and able to engage in Rebee exercises\n\nExclusion Criteria:\n\n1. Not under RDG: Total Knee Replacement \u002F Deconditioning\n2. Below 60 years old\n3. Unable to speak English\u002FMandarin\n4. Cognitive impaired, unable to follow instructions\n5. Has MDRO\n6. Not suitable to wear motion sensor on upper and lower limbs\n7. Refusal to participate \u002F give informed consent","60 Years","99 Years",{"count":55,"type":21},450,[24],"The study team proposes ATLAS (AI-Assisted TelerehabiLitAtion System) a two-part solution. The first-Rebee AI-assisted telerehabilitation device-assists in inpatient rehabilitation, and allows patients to continue with their physical rehabilitation when discharged and waiting for Day Rehabilitation Centre (DRC). The second-a structured programme to train and familiarise patients and caregivers to Rebee over patients' Community Hospital (CH) inpatient rehabilitation stay-adopts an evidence-based approach to increase uptake and adherence to Rebee.",[59,28],"Rehabilitation","NOT_YET_RECRUITING","2024-11-09",{"date":63,"type":37},"2024-11-12",{"date":65,"type":21},"2024-12",{"date":67,"type":21},"2025-11",{"name":69,"class":44},"SingHealth Community Hospitals"]