[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"delayed-gastric-emptying\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:delayed-gastric-emptying":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,48,76,103,134,166,198],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100652915","prevalence-and-measurement-of-delayed-gastric-emptying-in-patients-receiving-extracorporeal-membrane-oxygenation-100652915",false,"NCT07779174","Prevalence and Measurement of Delayed Gastric Emptying in Patients Receiving Extracorporeal Membrane Oxygenation","A Prospective Observational Study Exploring the Prevalence and Measurement of Delayed Gastric Emptying in Critically Ill Adults Receiving Extracorporeal Membrane Oxygenation","PROPEL-ECMO","* INCLUSION CRITERIA (non-ECMO group):\n\n  * Within 72 hours of Guy's \\& St Thomas' ICU admission\n  * Mechanically ventilated adults (≥18 years)\n  * Receiving enteral nutrition (liquid nutrition) via a gastric (nasogastric or orogastric) feeding tube\n  * Informed consent \u002F advice for participation by consultee\n  * Availability of study investigator or other trained healthcare professional on site to complete gastric emptying (stomach emptying) measurements\n* INCLUSION CRITERIA (ECMO group):\n\n  * Within 72 hours of Guy's \\& St Thomas' ICU admission\n  * Mechanically ventilated adults (≥18 years)\n  * Receiving enteral nutrition (liquid nutrition) via a gastric (nasogastric or orogastric) feeding tube\n  * Informed consent \u002F advice for participation by consultee\n  * Availability of study investigator or other trained healthcare professional on site to complete gastric emptying (stomach emptying) measurements\n  * Receiving either veno-venous or veno-arterial ECMO\n* EXCLUSION CRITERIA:\n\n  * Pregnancy\n  * History of gastroparesis (long-term slow stomach emptying)\n  * Current acute or long-term gastrointestinal pathology (stomach or bowel problem) that may influence gastric emptying (e.g. inflammatory bowel disease, coeliac disease, pancreatic exocrine insufficiency)\n  * Current contraindication to enteral nutrition (liquid nutrition) (e.g. clinical or radiological evidence of bowel obstruction, bowel ischaemia, ileus, upper gastrointestinal bleeding)\n  * Enteral nutrition (liquid nutrition) through a gastrostomy, jejunostomy or nasojejunal feeding tube\n  * Current or previous oesophageal, stomach or major small bowel surgery\n  * Known anatomical abnormality of the stomach (e.g. hiatus hernia)\n  * Pericardial \u002F abdominal drains or surgical wounds obstructing site of ultrasound scanning\n  * Nuclear medicine therapeutic administration, or diagnostic scintigraphy investigation in the previous 72 hours\n  * Unlikely to survive or withdrawal of life-sustaining treatment expected in the next 48 hours","ALL","18 Years","80 Years",{"count":21,"type":22},72,"ESTIMATED","OBSERVATIONAL","* The goal of this observational study is to learn whether the stomach takes longer to empty in patients on the intensive care unit who are receiving ECMO (a machine that temporarily takes over the role of the lungs and heart) compared to patients receiving support through a breathing machine (mechanical ventilation) only. It will also find the best way to measure stomach emptying at the bedside.\n* The main questions it aims to answer are:\n\n  * What is the prevalence of slow stomach emptying and other stomach or bowel problems in patients receiving ECMO, compared to patients receiving mechanical ventilation but not receiving ECMO? (Stage A)\n  * What is the best bedside method to measure stomach emptying in patients receiving ECMO? (Stage B)\n* Stage A of the study will involve measuring stomach emptying in study participants within four days of ICU admission, using two bedside methods:\n\n  * 'Residual volumes' (removing liquid nutrition left in the stomach with a syringe, after this has been given through the participant's usual feeding tube)\n  * A stomach ultrasound scan The researchers will check for differences between patients receiving ECMO versus no ECMO, and how this relates to the nutrition patients receive and how well or unwell they become in ICU.\n* In a smaller subgroup of patients receiving ECMO and participating in Stage B of the study, the researchers will also use scintigraphy. This is a standard research scan that tracks how the stomach empties by mixing a small, safe amount of radioactivity in the participant's usual liquid nutrition. The researchers will compare stomach emptying results from 'residual volumes' and stomach ultrasound with scintigraphy.",[26,27,28,29],"Gastric Emptying","Delayed Gastric Emptying","Critical Illness","ExtraCorporeal Membrane Oxygenation (ECMO)",[31,28,32,33,34],"Gastric emptying","Extracorporeal Membrane Oxygenation","Delayed gastric emptying","Nutrition","NOT_YET_RECRUITING","2026-08-19",{"date":38,"type":39},"2026-08-21","ACTUAL",{"date":41,"type":22},"2026-09",{"date":43,"type":22},"2028-06",{"name":45,"class":46},"Guy's and St Thomas' NHS Foundation Trust","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":74,"locationsCount":47},"100621827","hba1c-levels-and-gastric-emptying-assessed-by-gastric-ultrasound-100621827","NCT07375680","HbA1c Levels and Gastric Emptying Assessed by Gastric Ultrasound","Evaluation of the Effect of Hemoglobin A1c Levels on Gastric Emptying Assessed by Gastric Ultrasound","Inclusion Criteria:\n\nAdults aged 18 to 70 years. ASA physical status I-III. Scheduled for elective surgery under general anesthesia. Ability to provide written informed consent.\n\nExclusion Criteria:\n\nScheduled for emergency surgery. Refusal or inability to provide informed consent. Pregnancy. Age \\\u003C18 years or \\>70 years. History of gastric surgery. Neuromuscular disease. Current use of opioid or anticholinergic medications.","70 Years",{"count":57,"type":22},134,"Delayed gastric emptying increases the risk of pulmonary aspiration during general anesthesia. Diabetes mellitus and poor long-term glycemic control have been associated with impaired gastric motility. Hemoglobin A1c (HbA1c) is a marker of long-term glycemic control; however, its relationship with gastric emptying in surgical patients is not fully understood.\n\nThis prospective observational study aims to evaluate the association between HbA1c levels and gastric emptying using preoperative bedside gastric ultrasonography. Adult patients scheduled for elective surgery under general anesthesia will undergo gastric ultrasound examination after standard fasting. Gastric antral cross-sectional area and estimated gastric volume will be assessed and compared according to HbA1c levels.\n\nThe findings of this study may help improve preoperative risk stratification for aspiration and support individualized anesthetic management in patients with impaired glycemic control.",[27,60,61],"Diabetes Mellitus","Pulmonary Aspiration",[63,64,65,66],"Hemoglobin A1c","Gastric Ultrasonography","General Anesthesia","Preoperative Assessment","RECRUITING","2026-04-06",{"date":70,"type":39},"2026-04-08",{"date":72,"type":39},"2026-02-15",{"date":41,"type":22},{"name":75,"class":46},"Kutahya Health Sciences University",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":82,"sex":17,"minAge":83,"maxAge":18,"enrollmentInfo":84,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":86,"conditions":87,"keywords":91,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":47},"100491093","gastric-assessment-of-pediatric-patients-undergoing-surgery-100491093","NCT05674643","Gastric Assessment of Pediatric Patients Undergoing Surgery","Inclusion Criteria:\n\n* Perioperative patients with ASA classification 1-2\n* Ages: 2 years- less than 18 years\n* Locations: Longwood and Waltham campuses of Boston Childrens Hospital\n\nExclusion Criteria:\n\n* History of gastrointestinal surgery\n* Gastrostomy\n* Known GI dysmotility (cohort 1 only)\n* Acetaminophen allergy (cohort 1 only)\n* Liver or renal dysfunction- pre-diagnosed or, if available, when serum biomarkers are 2 standard deviations above the highest value considered normal for age. (cohort 1 only)\n* Consumption of acetaminophen in the 4 hours prior (cohort 1 only)",true,"2 Years",{"count":85,"type":22},60,"The goal of this pilot prospective cohort study is to examine the reproducibility of gastric volume and emptying as measured by gastric ultrasound and its correlation to a gold-standard test for gastric emptying in the perioperative period in pediatric patients. The main questions it aims to answer are:\n\n* What is the reliability (inter-rater variability between expert and novice assessors, and intra-rater variability) of a) the gastric antral cross-sectional area (CSA) and b) gastric volume using the Perlas US qualitative grading assessment, measured by using an ultrasound device in pediatric patients undergoing general anesthesia for elective surgery?\n* What is the correlation between ultrasound assessment of gastric emptying by the antral-CSA and gastric emptying determined by the acetaminophen absorption test (AAT), the gold standard?\n\nThe study will include two cohorts. Cohort assignment will be based on age and anesthesia induction plan. Subjects \\>7yrs of age and expected to get an IV induction will be assigned to Cohort #1. Subjects \\\u003C7yrs of age and not expected to get an IV induction will be assigned to Cohort #2.\n\n* Cohort 1 will include abdominal ultrasound for gastric assessment AND the acetaminophen absorption test which includes administering enteral acetaminophen (tylenol) with 6 oz of water and drawing of blood samples through a peripheral intravenous line.\n* Cohort 2 will include subjects for whom a peripheral intravenous line placement is not part of routine pre-operative care. Procedures for Cohort 2 will include abdominal ultrasound only in the pre-op area (no tylenol). This cohort is included to examine the reliability of measurements across age groups.",[88,27,89,90],"Fasting","Aspiration Pneumonia","Respiratory Aspiration of Gastric Content",[92,93],"gastric ultrasound","pre-operative fasting","2026-03-27",{"date":96,"type":39},"2026-04-02",{"date":98,"type":39},"2023-02-01",{"date":100,"type":22},"2028-12-31",{"name":102,"class":46},"Boston Children's Hospital",{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":110,"targetDuration":4,"studyType":112,"phases":113,"briefSummary":115,"conditions":116,"keywords":119,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":4},"100627650","intraoperative-pyloric-balloon-dilatation-to-reduce-delayed-gastric-emptying-after-pppd-100627650","NCT07451392","Intraoperative Pyloric Balloon Dilatation to Reduce Delayed Gastric Emptying After PPPD","Intraoperative Pyloric Balloon Dilatation to Decrease Post PPPD Delayed Gastric Emptying. Does It Help? RCT Study","Inclusion Criteria:\n\n* Adult patients (≥18 years) scheduled for elective PPPD due to tumors of the pancreatic head, distal bile duct, or ampulla of Vater.\n* Patients with no prior history of gastric surgery or severe gastroparesis.\n* Patients with no contraindications to balloon dilatation or intraoperative endoscopic procedures\n\nExclusion Criteria:\n\n* Patients with prior gastric surgery, pyloric stenosis, or history of severe gastroparesis.\n* Patients with severe comorbidities that may preclude safe surgery (ASA class IV or higher).\n* Patients who require emergency surgery or have unresectable disease.\n* Patients with active gastrointestinal bleeding or severe malnutrition",{"count":111,"type":22},70,"INTERVENTIONAL",[114],"NA","Pylorus-preserving pancreatoduodenectomy (PPPD) is a standard surgical treatment for tumors of the pancreatic head and surrounding areas. However, it is frequently associated with delayed gastric emptying (DGE), a complication that can lead to nausea, vomiting, and prolonged hospital stays. This study is a randomized controlled trial designed to evaluate if a simple intraoperative maneuver (pneumatic balloon dilatation of the pylorus) can reduce the incidence of early postoperative vomiting and DGE.\n\nParticipants will be randomly assigned to either the intervention group, receiving pyloric dilatation during surgery, or the control group, receiving standard surgery without dilatation. Researchers will monitor postoperative symptoms, gastric emptying function, and overall recovery to determine if this maneuver effectively improves patient outcomes.",[27,117,118],"Postoperative Nausea and Vomiting","Gastric Emptying Time",[27,120,121,122,123,124],"Pylorus-Preserving Pancreatoduodenectomy","PPPD","Pyloric Balloon Dilatation","Early Postoperative Vomiting","Pylorospasm","2026-02-28",{"date":127,"type":39},"2026-03-05",{"date":129,"type":22},"2026-04",{"date":131,"type":22},"2027-05",{"name":133,"class":46},"Assiut University",{"id":135,"slug":136,"hasResults":11,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":4,"eligibilityCriteria":140,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":141,"targetDuration":143,"studyType":23,"phases":4,"briefSummary":144,"conditions":145,"keywords":152,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":47},"100479104","compliance-with-eras-protocol-in-pancreatic-surgery-stress-response-and-outcomes-100479104","NCT05518643","Compliance With ERAS Protocol in Pancreatic Surgery, Stress Response and Outcomes","Enhanced Recovery Program, Patient Reported Outcomes, Surgery-specific Outcomes and Stress Response After Pancreatic Surgery: A Prospective Observational Cohort Study by the Thessalic Pancreas Study Group (ThePANas).","Inclusion Criteria:\n\n* all pancreatic surgery patients\n* above the age of 18\n* fluent greek speakers\n* without communication barriers\n\nExclusion Criteria:\n\n* younger than 18 years-old\n* unable or unwilling to participate\n* other surgical procedures\n* communication barriers\n* lost to follow-up",{"count":142,"type":22},120,"1 Year","The purpose of this study is to evaluate the impact of compliance with enhanced recovery after surgery (ERAS) program on patient reported outcomes (PROs), surgery-specific outcomes and stress response after pancreatic surgery.\n\nThis prospective observational study will include all consecutive patients undergoing pancreatic surgery over a period of three years (2022 - 2025) at two sites, namely University General Hospital of Larissa and IASO Thessalias, in Greece. Patients will be prospectively enrolled after written informed consent. Data will be collected on patient characteristics, surgical and anaesthetic techniques, complications, and length of stay. Quality of life questionnaires will be administered to patients preoperatively, on the fith postoperative day, first follow-up after discharge, one month and six months after the operation. The stress response will be assessed by measuring the Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio (NLR and PLR) preoperatively, and on the first five postoperative days. Data will be collected on pancreatic surgery-specific complications such as delayed gastric emptying (DGE), post-pancreatectomy haemorrhage (PPH) and postoperative pancreatic fistula (POPF) formation. Anonymised data will be uploaded by the principal investigator on a protected excel spreadsheet for analysis.",[146,147,148,27,149,150,151],"ERAS","Pancreas Cancer","Pancreas; Fistula","Surgery-Complications","Pancreatic Hemorrhage","PROMs",[146,147,151,153,149,154,155,156],"Stress response to surgery","PLR","NLR","Quality of Life","2025-04-16",{"date":159,"type":39},"2025-04-22",{"date":161,"type":39},"2022-07-15",{"date":163,"type":22},"2025-06",{"name":165,"class":46},"University of Thessaly",{"id":167,"slug":168,"hasResults":11,"nctId":169,"briefTitle":170,"officialTitle":171,"acronym":172,"eligibilityCriteria":173,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":174,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":176,"conditions":177,"keywords":184,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":189,"lastUpdatePostDateStruct":190,"startDateStruct":192,"completionDateStruct":194,"leadSponsor":196,"locationsCount":47},"100567777","intra-abdominal-hypertension-and-abdominal-compartment-syndrome-in-patients-after-pancreatic-procedures-100567777","NCT06672601","Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures.","The HYPA Study: Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients Undergoing Open and Robotic Pancreatic Procedures","HYPA","Inclusion Criteria:\n\n* Patients ≥ 18-year-old\n* Indication for elective pancreatic procedure\n* Written informed consent\n\nExclusion Criteria:\n\n* Patients \\\u003C18 years old.\n* Contraindication for urinary catheter placement.\n* Refusal to participate in the study.",{"count":175,"type":22},150,"This study investigates the development of intra-abdominal hypertension and compartment syndrome in patients undergoing elective pancreatic procedures. Main objective is to determine the proportion of patients after pancreatic operation who develop elevated intra-abdominal pressure and assess its association with postoperative complication rates. Another goal of the study is to compare open versus robotic pancreatic procedures regarding the occurrence of intra-abdominal hypertension and abdominal compartment syndrome.",[178,179,180,181,27,182,183],"Intra Abdominal Pressure","Abdominal Compartment Syndrome","Pancreatic Surgery","Pancreatic Fistula After Pancreaticoduodenectomy","Anastomotic Leaks","Overload Fluid",[185,186,187,188],"Intra-abdominal hypertension","Compartment syndrome","Pancreatic surgery","Robotic surgery","2024-11-07",{"date":191,"type":39},"2024-11-08",{"date":193,"type":22},"2025-01-01",{"date":195,"type":22},"2028-03-31",{"name":197,"class":46},"Charles University, Czech Republic",{"id":199,"slug":200,"hasResults":11,"nctId":201,"briefTitle":202,"officialTitle":202,"acronym":4,"eligibilityCriteria":203,"healthyVolunteers":11,"sex":17,"minAge":204,"maxAge":4,"enrollmentInfo":205,"targetDuration":4,"studyType":112,"phases":207,"briefSummary":208,"conditions":209,"keywords":214,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":219,"lastUpdatePostDateStruct":220,"startDateStruct":222,"completionDateStruct":224,"leadSponsor":226,"locationsCount":47},"100550891","the-impact-and-effect-of-traditional-chinese-medicine-treatment-on-organ-failure-in-critically-ill-patients-100550891","NCT06452966","The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients","Inclusion Criteria:\n\n* Age 20 and above\n* Surgical ICU patients\n* The use of Chinese medicine must be approved by the attending physician in the surgical intensive care unit\n\nExclusion criteria:\n\n* Patients' family members refuse TCM intervention","20 Years",{"count":206,"type":22},350,[114],"Critically ill patients are at risk of or suffering from one or more key organs or organ system failure. This study will measure the effect of traditional Chinese medicine(TCM) interventions on critically ill patients admitted to the intensive care unit (ICU).\n\nThe goal of this clinical trial is to learn if traditional Chinese medicine(TCM) is effective for prevention and treatment of organ failure in ICU patients. Patients in this group will receive intervention for 2 weeks.\n\nA multi-center non-randomized real word data study, will include 3 groups: intervention group (TCM)(n=70), control group and historical control group (admitted to the same ICU in the period of 01.2019 to 12.2023).\n\nMain outcomes include sequential organ failure assessment (SOFA) score, ICU length of stay, hospital length of stay, number of days of respirator uses and western medicine medication used study follow up will be 2 weeks.",[210,211,27,212,213],"Organ Failure, Multiple","Indigestion","Respiratory Failure","Morality",[215,216,217,218],"acupuncture","chinese medicine","Organ Failure","intensive care","2024-06-06",{"date":221,"type":39},"2024-06-11",{"date":223,"type":39},"2024-05-07",{"date":225,"type":22},"2027-05-30",{"name":227,"class":46},"China Medical University Hospital"]