[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dental-extraction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dental-extraction":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100647610","insomnia-and-post-dental-surgery-pain-a-prospective-study-100647610",false,"NCT07712432","Insomnia and Post-Dental Surgery Pain: A Prospective Study","Effect of Insomnia on Post-operative Dental Surgical Pain: a Prospective Observational Study in an Adult Population.","INDOLC","Inclusion Criteria:\n\n* Age over or egual 18 years.\n* Need for odontoiatric surgical intervention (dental extractions).\n* Willingness to participate in the study by completing the proposed questionnaires.\n* Good understanding of the Italian language.\n* Ability to understand and sign the informed consent form.\n\nExclusion Criteria:\n\n* Pharmacological therapy interfering with sleep or pain at the time of recruitment.\n* Acute pain or ongoing infections at the time of recruitment.\n* Relevant comorbidities.\n* Pregnancy.\n* Impossibility to complete the follow-up.","ALL","18 Years",{"count":20,"type":21},90,"ESTIMATED","OBSERVATIONAL","The purpose of this prospective observational study is to evaluate the relationship between preoperative sleep disturbances-specifically insomnia-and postoperative pain intensity following oral surgical procedures. Recent scientific literature highlights a bidirectional relationship between sleep disorders and pain in dentistry, suggesting that disturbed sleep may actively exacerbate subsequent pain perception. Although postoperative pain, swelling, and masticatory difficulties are common after dental extractions, clinical data investigating the direct impact of preoperative sleep quality on these surgical outcomes remain scarce. This study will enroll adult patients undergoing routine dental extractions and allocate them into two cohorts based on their baseline sleep quality: patients without preoperative sleep disturbances and patients with preoperative sleep disturbances. Pain levels and sleep parameters will be assessed using validated questionnaires before the surgery and at a 7-day follow-up. The primary objective is to determine whether the presence of preoperative insomnia leads to a significant increase in perceived postoperative surgical pain.",[25,26,27],"Dental","Dental Extraction","Insomnia",[27,29],"Oral disease","NOT_YET_RECRUITING","2026-07-14",{"date":33,"type":34},"2026-07-17","ACTUAL",{"date":36,"type":21},"2026-06",{"date":38,"type":21},"2027-06",{"name":40,"class":41},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":49,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":66,"locationsCount":42},"100537281","mix-of-demineralized-freeze-dried-bone-allograft-and-deproteinized-bovine-bone-mineral-a-possible-solution-for-alveolar-ridge-preservation-100537281","NCT06275789","Mix of Demineralized Freeze-Dried Bone Allograft and Deproteinized Bovine Bone Mineral: a Possible Solution for Alveolar Ridge Preservation?","Inclusion Criteria:\n\n* Patients in good health\n* Require the extraction of at least one premolar or molar with future implant placement\n* Sufficient keratinized gingiva (equal or more than 2mm prior to extraction),\n* No more than 3mm of buccal bone loss\n* Flapless extraction possible\n* Full mouth plaque index of less than 25%\n\nExclusion Criteria:\n\n* Nicotine consumption equivalent to or more than 10 cigarettes per day\n* Electronic cigarette usage\n* A history of irradiation of head and neck area\n* Immunodeficiency disease\n* Uncontrolled systemic health problems (hypertension crisis 180\u002F120, hyperthyroidism, diabetes with HbA1c over 7, recent history of stroke, cancer) History of medications that affect bone remodeling process (bisphosphonates, RANK-L inhibitors)\n* Previous adverse reaction to the biomaterials used\n* Pregnancy\u002Flactation, or those who are trying to become pregnant.\n* Active uncontrolled or untreated periodontal disease\n* Periapical lesions greater than 1 cm and soft tissue pathology",true,{"count":51,"type":21},30,"INTERVENTIONAL",[54],"NA","The purpose of the study is to compare a new grafting material for alveolar ridge preservation to a commonly used and well studied material. Alveolar ridge dimensions as well as histology will be compared.",[57,26,58],"Alveolar Ridge Preservation","Bone Graft","RECRUITING","2025-09-05",{"date":62,"type":34},"2025-09-12",{"date":64,"type":34},"2024-01-26",{"date":36,"type":21},{"name":67,"class":41},"Nova Southeastern University"]