[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dental\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dental":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,43,67,97],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100647610","insomnia-and-post-dental-surgery-pain-a-prospective-study-100647610",false,"NCT07712432","Insomnia and Post-Dental Surgery Pain: A Prospective Study","Effect of Insomnia on Post-operative Dental Surgical Pain: a Prospective Observational Study in an Adult Population.","INDOLC","Inclusion Criteria:\n\n* Age over or egual 18 years.\n* Need for odontoiatric surgical intervention (dental extractions).\n* Willingness to participate in the study by completing the proposed questionnaires.\n* Good understanding of the Italian language.\n* Ability to understand and sign the informed consent form.\n\nExclusion Criteria:\n\n* Pharmacological therapy interfering with sleep or pain at the time of recruitment.\n* Acute pain or ongoing infections at the time of recruitment.\n* Relevant comorbidities.\n* Pregnancy.\n* Impossibility to complete the follow-up.","ALL","18 Years",{"count":20,"type":21},90,"ESTIMATED","OBSERVATIONAL","The purpose of this prospective observational study is to evaluate the relationship between preoperative sleep disturbances-specifically insomnia-and postoperative pain intensity following oral surgical procedures. Recent scientific literature highlights a bidirectional relationship between sleep disorders and pain in dentistry, suggesting that disturbed sleep may actively exacerbate subsequent pain perception. Although postoperative pain, swelling, and masticatory difficulties are common after dental extractions, clinical data investigating the direct impact of preoperative sleep quality on these surgical outcomes remain scarce. This study will enroll adult patients undergoing routine dental extractions and allocate them into two cohorts based on their baseline sleep quality: patients without preoperative sleep disturbances and patients with preoperative sleep disturbances. Pain levels and sleep parameters will be assessed using validated questionnaires before the surgery and at a 7-day follow-up. The primary objective is to determine whether the presence of preoperative insomnia leads to a significant increase in perceived postoperative surgical pain.",[25,26,27],"Dental","Dental Extraction","Insomnia",[27,29],"Oral disease","NOT_YET_RECRUITING","2026-07-14",{"date":33,"type":34},"2026-07-17","ACTUAL",{"date":36,"type":21},"2026-06",{"date":38,"type":21},"2027-06",{"name":40,"class":41},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":42},"100547120","impact-of-preoperative-dental-screening-in-reducing-infective-endocarditis-risk-in-surgical-valve-replacement-patients-100547120","NCT06403839","Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Surgical Valve Replacement Patients","Impact of Targeted Preoperative Dental Screening on Post-procedural Risk of Infective Endocarditis in Patients Undergoing Surgical Valve Replacement: a Prospective Observational Study","DENSVAR","Inclusion Criteria:\n\n* Patients undergoing surgical valve replacement\n\nExclusion Criteria:\n\n* None",{"count":52,"type":21},1000,"In Odense University Hospital preoperative dental screening (PDS) protocol for patients treated with surgical valve replacement was changed from mandatory to targeted PDS to from march 2024.\n\nThe investigators will therefore compare the risk of IE before vs after march 2024.",[55,25,56],"Surgical Valve Replacement","Endocarditis","RECRUITING","2025-08-12",{"date":60,"type":34},"2025-08-15",{"date":62,"type":34},"2020-01-01",{"date":64,"type":21},"2028-03-01",{"name":66,"class":41},"Odense University Hospital",{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":4,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":17,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":4,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":86,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":4},"100585323","the-effect-of-bulk-filling-flowable-composite-on-caries-recurrence-in-deep-marginal-elevation-a-randomized-clinical-trial-100585323","NCT06900868","The Effect of Bulk Filling Flowable Composite on Caries Recurrence in Deep Marginal Elevation: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Adults patients (20-50)\n* Good oral hygiene (plaque index 0 or 1 )\n* Patient approving to participate in the study\n* Absence of parafunctional habits and\u002For bruxism\n* No sign of irreversible pulpitis\n* No periapical radiolucency\n* Deep subgingival margin\n* Molars class II with subgingival margin\n\nExclusion Criteria:\n\n* • Patients with known allergic or adverse reaction to the tested materials.\n\n  * Systematic disease that may affect participation.\n  * Xerostomic patients.\n  * Bad oral hygiene (plaque index 2 or 3 )\n  * Heavy smokers\n  * Patients undergoing or will start orthodontic treatment\n  * Patients with removable prothesis",true,"20 Years","50 Years",{"count":77,"type":21},50,"INTERVENTIONAL",[80],"NA","Deep marginal elevation usinge a bioactive dental material in deep subgingival Class II restorations, S-PRG filler-containing materials offer significant benefits due to their bioactive properties, Their ability to release fluoride, remineralization potential and acid neutralization, reducing the risk of recurrent caries, particularly at the gingival margin(Imazato et al. 2023). The antibacterial and antifungal effects help inhibit biofilm formation, enhancing the longevity of restorations. Additionally, these materials support better marginal adaptation by reducing microleakage and improving bond durability (Imazato et al. 2023) This type of composite may improve the outcomes of deep subgingival margin elevation, benefiting both restorative success and periodontal health(Imazato et al. 2023).",[83,84,25,85],"DME","Dental Caries","Deep Margin Elevation",[87],"Deep margin elevation","2025-03-22",{"date":90,"type":34},"2025-03-28",{"date":92,"type":21},"2025-03-20",{"date":94,"type":21},"2026-04-20",{"name":96,"class":41},"Future University in Egypt",{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":73,"sex":17,"minAge":74,"maxAge":75,"enrollmentInfo":105,"targetDuration":4,"studyType":78,"phases":106,"briefSummary":107,"conditions":108,"keywords":109,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":4},"100583378","clinical-performance-of-high-viscosity-bioactive-injectable-composite-in-deep-marginal-elevation-100583378","NCT06875544","Clinical Performance of High Viscosity Bioactive Injectable Composite in Deep Marginal Elevation","Clinical Performance of High Viscosity Bioactive Injectable Composite in Deep Marginal Elevation Randomized Controlled Trail","Randomized","Inclusion Criteria:\n\n1. Adult Patient (20-50 years old)\n2. Good oral hygiene (plaque index 0 or 1)\n3. Patient approval\n4. Absence of parafunctional habits and\u002For bruxism\n5. No endodontic treatment\n6. No abscess\n7. No partial or fixed denture\n\nExclusion Criteria:\n\n1. Patients with known allergic or adverse reaction to the tested materials.\n2. Bad oral hygiene\n3. Systematic disease that may affect participation.\n4. Xerostomic patients.\n5. Patients with active periodontal disease.\n6. Heavy smokers (those who smoke greater than or equal to 25 or more cigarettes a day)\n7. Orthodontic treatment patient",{"count":77,"type":21},[80],"Using a bioactive resin composite in subgingival Class II cavities can provide enhanced caries resistance by releasing multiple ions, including fluoride. This approach offers greater resistance to caries due to the incorporation of surface pre-reacted glass filler (S-PRG) technology (Imazato, Nakatsuka et al., 2023).\n\nThis type of composite may improve the outcomes of deep subgingival margin elevation, benefiting both restorative success and periodontal health.",[83,25,85],[110],"deep margin elevation","2025-03-08",{"date":113,"type":34},"2025-03-13",{"date":115,"type":21},"2025-03",{"date":117,"type":21},"2026-04",{"name":96,"class":41}]