[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"denture-complete\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:denture-complete":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100646307","nutritional-intervention-for-older-adults-with-complete-dentures-100646307",false,"NCT07692828","Nutritional Intervention for Older Adults With Complete Dentures","Novel Dietary Guidelines for Elderly Denture-wearers to Ensure Adequate Nutritional Intake, Good Quality of Life and Enhanced Performance on Cognitive Tasks","Inclusion Criteria:\n\n* Men and women aged 60 to 80 years.\n* Systemically healthy individuals or those with controlled chronic systemic conditions under regular medical supervision.\n* Functionally independent individuals, or those with a dedicated family member or caregiver available to provide support throughout the study period.\n* Wearers of both maxillary and mandibular complete removable dentures.\n* Adequate stability, retention, and functionality of both complete dentures allowing the participant to chew effectively during daily meals (accepting minor retention or stability limitations in the mandibular prosthesis, provided routine functional mastication is maintained).\n* Acceptable centric occlusion and jaw relationship allowing functional mastication.\n* Intact oral mucosa without active lesions or severe soreness in the denture-bearing areas.\n\nExclusion Criteria:\n\n* Altered salivary flow (hyposalivation or xerostomia) identified via anamnesis and sialometry, with an unstimulated salivary flow rate \\\u003C 0.1 mL\u002Fmin or a stimulated salivary flow rate \\\u003C 0.5 mL\u002Fmin.\n* Active oral mucosa diseases or lesions (e.g., cheilitis, denture stomatitis, ulcers, or aphthae) verified through intraoral examination.\n* Diagnosis of a major neurocognitive disorder by a qualified professional, verified via medical records and\u002For caregiver interview.\n* Color blindness (daltonism or color vision deficiency).\n* Presence of signs or symptoms of temporomandibular disorders (TMD).\n* Known history of allergy to peanuts or latex.\n* Underweight or severe undernutrition, defined as a Body Mass Index (BMI) \\\u003C 18.5 kg\u002Fm².","ALL","60 Years","80 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this clinical trial is to test a nutritional intervention. This study helps older adults who wear complete removable dentures improve their health.\n\nThe main questions the study aims to answer are:\n\n* What are the participants life experiences living with complete dentures before the intervention?\n* Does the intervention improve the diet quality of the participants?\n* Does the intervention improve nutritional status of the participants?\n* Does the intervention improve chewing performance and muscle strength?\n* Does the intervention increase the thickness of the masticatory muscles?\n* Does the intervention improve stress and muscle health markers in saliva?\n* Does the intervention improve cognitive performance and oral health-related quality of life?\n* Does the intervention improve cerebral blood flow? The study will include a total of 40 participants, who will be assigned to two groups. One group of 20 participants will receive the nutritional intervention, while the other group of 20 participants will maintain their usual diet during the study period. This comparison will allow the investigators to assess the effectiveness of the intervention.\n\nParticipants will:\n\n* Take part in a personal interview about their life experience with dentures.\n* Follow a dietary guide with recommendations on specific food textures for six months.\n* Receive personalized nutritional counseling and participate in healthy cooking workshops.\n* Use a custom-built mobile application to access the educational content of the nutritional guide, view instructional videos uploaded biweekly, and receive automated reminder notifications.\n* Attend clinical follow-up assessments, including chewing performance, muscle assessment, saliva markers, assessment of diet quality and nutritional status, cognitive tests, and oral health-related quality of life.\n* Complete these assessments at three main time points: baseline, 3 months, and 6 months.",[27,28,29],"Edentulism Complete","Denture, Complete","Mastication Disorder",[31,32,33,34,35,36],"Nutritional Intervention","Older Adults","Salivary Biomarkers","Cognitive Performance","OHRQoL","Masticatory Performance","NOT_YET_RECRUITING","2026-07-07",{"date":40,"type":41},"2026-07-09","ACTUAL",{"date":40,"type":21},{"date":44,"type":21},"2028-05-12",{"name":46,"class":47},"Universidad de La Frontera","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":57,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":48},"100569009","examining-the-effects-of-removable-denture-use-in-patients-over-60-years-of-age-100569009","NCT06688669","Examining the Effects of Removable Denture Use in Patients Over 60 Years of Age","Examining the Effects of Removable Denture on Behavior and Cognitive Skills in Geriatric Patients","Inclusion Criteria:\n\n* Patients over the age of 60\n* No systemic condition that would prevent the fabrication of removable dentures\n* Need for new removable dentures for both jaws\n* Ability to read and understand the questions in the tests and surveys\n* No barriers to communication or self-expression\n* No significant physical disability affecting functionality\n* No history of cancer or surgical operation in the head and neck region\n* No conditions or medications that could limit test performance (e.g., Parkinson's disease)\n\nExclusion Criteria:\n\n* Patients under the age of 60\n* Patients who do not require new removable dentures\n* Patients whose missing teeth can be restored with fixed prosthetic restorations and who do not need removable dentures\n* Patients who are illiterate\n* Patients with systemic conditions that prevent the fabrication of removable dentures\n* Patients with conditions like Parkinson's disease that could restrict test performance or who use medications with side effects causing unwanted convulsions\n* Patients with significant balance issues, who frequently lose balance while walking\n* Geriatric patients with temporary or permanent memory loss\n* Patients with any history of cancer in the head and neck region\n* Patients with severe difficulty in communication and self-expression\n* Patients who are not willing to participate in the study",{"count":20,"type":21},"3 Months","OBSERVATIONAL","Patients over the age of 60 who do not currently have any removable dentures but require them will be included in the study. Patients who will receive complete dentures and those who will receive partial dentures will be assessed in separate groups. Before the fabrication of the dentures, the Mini-Mental State Examination Test (MMSE), the physical normative value test (TUG), and the Oral Functional Capacity (OFC) scoring will be conducted. No intervention will be made to the treatment during the prosthetic treatment process.\n\nThe same questionnaires will be administered again three weeks after the completion of the prosthetic treatments. The impact of the use of removable dentures on test results will be evaluated. Additionally, during this session, patients will complete a patient satisfaction test regarding their dentures (OHIP-14 for patients with a removable partial denture indication, and OHIP-edent for patients with a complete denture indication). Patients will be called back after three months, and all tests will be repeated. The relationship between the Mini-Mental State Examination, the TUG test, and the OFC test with patient satisfaction will be assessed and any changes in test scores related to denture use will be investigated.",[61,28,62],"Edentulism","Denture, Partial, Removable",[64,65,66,67],"complete denture","removable partial denture","OHIP-14","mini mental state examination","RECRUITING","2024-11-12",{"date":71,"type":41},"2024-11-14",{"date":73,"type":41},"2024-10-25",{"date":75,"type":21},"2025-05-01",{"name":77,"class":47},"Istanbul University"]