[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"depression-and-anxiety-symptoms\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:depression-and-anxiety-symptoms":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,46,73,111],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100652568","remote-group-cognitive-behavioral-skills-training-for-mexican-university-students-with-anxiety-or-depression-100652568",false,"NCT07776236","Remote Group Cognitive Behavioral Skills Training for Mexican University Students With Anxiety or Depression","Study of the Cultural Adaptation, Implementation, and Effectiveness of an Online Group Cognitive-behavioral Skills Training Program to Reduce Anxiety and Depression Among University Students","Inclusion Criteria:\n\n* Undergraduate student enrolled in one of the participating universities\n* At least 18 years of age\n* Scoring 10 or more points on the PHQ-9 or the GAD-7\n* Provide informed consent\n\nExclusion Criteria:\n\n* Report that a professional gave them a diagnosis of bipolar disorder or psychosis","ALL","18 Years",{"count":19,"type":20},400,"ESTIMATED","INTERVENTIONAL",[23],"NA","The aim is to assess the effectiveness of remote group cognitive behavioral skills training for reducing symptoms of depression and anxiety among university students in Mexico. The investigators will conduct a two-arm randomised control trial comparing a 10-session online group CBT intervention to a mood monitoring web-based application as an active control group.",[26],"Depression and Anxiety Symptoms",[28,29,30,31,32,33],"depression","anxiety","cognitive behavioral","Mexico","university students","remote group therapy","NOT_YET_RECRUITING","2026-08-19",{"date":37,"type":38},"2026-08-21","ACTUAL",{"date":40,"type":20},"2026-08-18",{"date":42,"type":20},"2029-03",{"name":44,"class":45},"Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente","OTHER",{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":21,"phases":56,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":4},"100652572","ipv-prevention-among-fdp-100652572","NCT07775677","IPV Prevention Among FDP","Adaptation and Pilot Trial of an Intervention to Reduce Intimate Partner Violence and Mental Health Symptoms Among Forcibly Displaced Resettled Congolese Populations in the United States","Inclusion Criteria:\n\n* couples who are:\n\n  * 18 years or older\n  * Married or in a relationship and currently living with your spouse \u002F partner\n  * Came to the U.S. within the past 5 years\n  * Originally from the Democratic Republic of Congo\n  * Fluent in Kinyarwanda, Kinyamulenge, and\u002For Kinyabwisha\n  * Current or past client of the International Rescue Committee\n\nExclusion Criteria:\n\n* 1\\) not fluent in Kinyarwanda, Kinyamulenge or Kinyabwisha, 2) people who are currently seeking legal protection against an abusive partner and\u002For are engaged in IRC provided case management services for IPV.",true,{"count":55,"type":20},107,[23],"Forcibly displaced women and their male partners experience compounding social and structural vulnerabilities to intimate partner violence (IPV) and mental health challenges, yet rigorous studies or examples of evidence-based interventions that seek to prevent and reduce IPV and mental health problems among forcibly displaced populations (FDPs) who seek asylum and rebuild their lives in the United States (US) are scarce. Guided by the the Assessment, Decision, Adaptation, Production, Topical experts-integration, Training, and Testing (ADAPT-ITT) framework, Cascade Implementation Framework, and NIMH experimental therapeutics approach, we propose to address this gap in research and practice by (1) adapting the Economic and Social Empowerment (EA$E) curriculum for US-based FD Congolese couples, (2) using a hybrid type 2 pilot study design to explore preliminary effects of EA$E-US on IPV, mental health outcomes and intermediary outcomes, and (3) examining implementation processes and outcomes",[59,60,26],"PTSD Symptoms","Violence Prevention",[62,63,64],"violence prevention","implementation research","mental health",{"date":66,"type":38},"2026-08-20",{"date":68,"type":20},"2026-11",{"date":70,"type":20},"2028-06-30",{"name":72,"class":45},"George Mason University",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":21,"phases":84,"briefSummary":85,"conditions":86,"keywords":91,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":110},"100651050","cancog-pilot-trial-of-cognitive-rehabilitation-for-cancer-survivors-100651050","NCT07755839","CanCOG®: Pilot Trial of Cognitive Rehabilitation for Cancer Survivors","CanCOG® - Cognitive Rehabilitation in Cancer: A Protocol for a Multicenter Pilot Randomized Controlled Trial With Non-central Nervous System Cancer Survivors","CanCOG®","Inclusion Criteria:\n\n* Adults aged 18 to 65 years whose native language is European Portuguese;\n* Diagnosis of cancer not involving the central nervous system (non-CNS cancer);\n* Disease stage I to III;\n* Completion of primary cancer treatment at least 6 months and no more than 5 years prior to enrollment (with the exception of ongoing hormone therapy and immunotherapy);\n* Score \\\u003C 51 on the Perceived Cognitive Abilities subscale of the FACT-Cog v3. Stable psychiatric and neurological medication regimen for at least 3 months prior to enrollment;\n* Educational level equal to or higher than the 3rd year of primary education;\n* Ability to read and write in Portuguese and provide informed consent to participate.\n\nExclusion Criteria:\n\n* Diagnosis of current severe psychiatric disorders (e.g., schizophrenia, psychosis, bipolar disorder, major depressive disorder, or attention-deficit\u002Fhyperactivity disorder);\n* Diagnosis of communication disorders;\n* Diagnosis of neurodevelopmental disorders or other severe medical conditions (e.g., history of stroke, encephalitis, dementia or neurodegenerative disease, epilepsy, or traumatic brain injury);\n* Presence of metastases or other tumors;\n* History of substance abuse (alcohol or drugs);\n* Current or prior participation in another cognitive rehabilitation intervention.","65 Years",{"count":83,"type":20},60,[23],"Cancer-related cognitive impairment (CRCI) affects a large proportion of non-central nervous system cancer survivors and can negatively impact cognitive functioning and daily life. Cognitive rehabilitation has shown promising results in addressing these difficulties. The goal of this pilot randomized controlled trial is to evaluate the feasibility, acceptability, and preliminary efficacy of the CanCOG®- Cognitive Rehabilitation in Cancer program in Portuguese adult cancer survivors with CRCI.\n\nAdult non-central nervous system cancer survivors (n=60) will be randomly assigned to receive either the CanCOG® intervention or treatment as usual.\n\nCanCOG® is a structured cognitive rehabilitation program designed to help cancer survivors manage cognitive difficulties through cognitive training exercises, psychoeducation, and compensatory strategy training. The program consists of six weekly sessions of 1 hour and 30 minutes each, delivered over six consecutive weeks. Sessions are administered in person in small groups (3-9 participants) and are led by a trained professional.\n\nThe main focus of the study is to assess feasibility outcomes, including recruitment, retention, adherence to the intervention, and completion of study assessments, as well as acceptability and participant satisfaction.\n\nThe study will also explore preliminary effects of the intervention on cognitive functioning (both perceived and objective), symptoms of anxiety and depression, and quality of life. Participants will complete assessments at baseline (2 weeks after the intervention), 2 weeks after the intervention, and at 3- and 6-month follow-ups. Some participants (10-15) will also take part in interviews to provide feedback on their experience with the program.",[87,88,89,26,90],"Cancer-related Cognitive Impairment","Cancer-related Cognitive Dysfunction","Cancer-related Cognitive Difficulties","Quality of Life",[92,93,94,95,96,97,98,99,100],"cancer","cancer survivors","cognitive rehabilitation","cognition","non-pharmacological interventions","RCT","Pilot study","crci","cancer-related cognitive impairment","2026-08-07",{"date":103,"type":38},"2026-08-10",{"date":105,"type":20},"2026-09",{"date":107,"type":20},"2028-05",{"name":109,"class":45},"Aveiro University",1,{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":4,"eligibilityCriteria":117,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":118,"targetDuration":4,"studyType":21,"phases":120,"briefSummary":122,"conditions":123,"keywords":126,"overallStatus":129,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":110},"100644752","phase-2-leveraging-mhealth-to-promote-opioid-use-recovery-and-mental-health-among-residents-of-a-medium-sized-midwestern-city-100644752","NCT07673380","Leveraging mHealth to Promote Opioid Use Recovery and Mental Health Among Residents of a Medium-Sized Midwestern City","Leveraging mHealth to Promote Recovery From Opioid Use Disorder and Commonly Occurring Mental Health Disorders Among Residents of a Medium-Sized Midwestern City","Inclusion Criteria:\n\n* Have a history of opioid and\u002For stimulant use\n* Identify as Black and\u002For African American\n* Seek treatment at local substance use treatment centers\n* Fluent in English\n* U.S. resident\n* 18 years of age or older at the time of data collection.\n\nExclusion Criteria:\n\n* Self-reported cognitive impairment that would limit ability to participate in research.",{"count":119,"type":20},300,[121],"PHASE2","The sequential trial compares recovery and mHealth engagement outcomes among Black participants who participated in the mHealth intervention uMAT-R or uMAT-R + enhanced community engagement. The mHealth intervention seeks to support people in various stages of recovery who are also seeking other forms of substance use treatment. Participants are recruited from community-based substance use treatment facilities and recovery services. Participants must be adults who have or are currently using opioids and\u002For stimulants.",[124,125,26],"Opioid Use","Stimulant Use",[127,128],"Digital health","Community engagement","RECRUITING","2026-06-22",{"date":132,"type":38},"2026-06-29",{"date":134,"type":38},"2025-08-31",{"date":136,"type":20},"2027-02-28",{"name":138,"class":45},"Washington University School of Medicine"]