[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"depression-during-the-menopausal-transition\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:depression-during-the-menopausal-transition":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100568258","sleep-and-light-intervention-sali-for-menopausal-mood-dysfunction-100568258",false,"NCT06678880","Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction","Chronobiological Basis of Depression During the Menopause Transition","SALI","Inclusion Criteria:\n\n* Women aged 45-75 years old\n* Experiencing significant down, sad or hopeless feelings that are affecting their daily life\n* These mood changes started or got worse during the menopause transition\n* Irregular or no menstrual cycle for at least 6 months\n* Non-smoking\n* Located in San Diego County\n\nExclusion Criteria:\n\n* Untreated sleep apnea\n* Migraine headaches that are triggered or worsened by bright light\n* Currently suicidal or psychotic\n* History of bipolar disorder\n* A medical condition or job where fatigue or changes in sleep schedule could be unsafe\n* Planning to start, stop, or change medications in the next 4 months","FEMALE","45 Years","75 Years",{"count":21,"type":22},120,"ESTIMATED","INTERVENTIONAL",[25],"NA","\\*\\*Participants must live in San Diego County\\*\\*\n\nThe purpose of this study is to learn more about an experimental Sleep \\& Light Intervention (SALI) for menopausal mood changes or depression. Researchers want to find out whether adjusting the body's internal clock-which helps regulate sleep, hormones, mood, and energy- can improve symptoms such as depression, poor sleep, and low energy during menopause.",[28,29,30],"Depression","Depression During the Menopausal Transition","Menopausal Depression",[32,33,34,35,36,37],"Menopause","depression","sleep and light intervention","melatonin","circadian rhythm","Chronobiology","RECRUITING","2026-08-03",{"date":41,"type":42},"2026-08-05","ACTUAL",{"date":44,"type":42},"2025-03-11",{"date":46,"type":22},"2029-02-28",{"name":48,"class":49},"University of California, San Diego","OTHER"]