[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"developmental-dysplasia-of-the-hip-ddh\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:developmental-dysplasia-of-the-hip-ddh":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,85],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100651224","manual-intervention-and-congenital-hip-dysplasia-in-infants-100651224",false,"NCT07756814","Manual Intervention and Congenital Hip Dysplasia in Infants","Exploring a Manual Intervention on the Coxal Bone in Infants With Congenital Hip Dysplasia: A Pilot Study","Inclusion Criteria:\n\n* Confirmed diagnosis of DDH, unilateral or bilateral\n* Graf score between IIa and III (moderate to severe DDH), as stage I may resolve spontaneously\n* Written parental authorization (or delegated parental representation) providing free and informed consent\n* Infant already receiving conservative orthopedic care with a Pavlik harness (the study tests a complementary intervention)\n* Parental availability for the study follow-up\n\nExclusion Criteria:\n\n* Presence of severe congenital anomalies\n* Neuromuscular or genetic diseases affecting muscle tone or bone growth\n* Cardiorespiratory conditions requiring constant monitoring\n* Fractures of the pelvis or lower limbs\n* Prematurity (birth before 37 weeks of gestation)\n* Medical contraindications to the proposed manual intervention\n* Ongoing physiotherapy or any manual therapy treatment outside the study framework\n* Growth retardation (staturo-ponderal), with or without suspected nutritional deficiencies\n* Infant showing distress or intolerance to physical handling during prior care\n* Simultaneous participation in another clinical study","ALL","1 Month","5 Months",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","Developmental dysplasia of the hip (DDH) is a developmental abnormality of the infant hip in which the acetabulum does not adequately cover the femoral head. Standard conservative treatment commonly includes a Pavlik harness. This exploratory randomized pilot study will assess whether a gentle manual intervention applied to the coxal bone, in addition to conventional orthopedic treatment, is associated with a greater change in ultrasound-measured femoral head coverage than conventional orthopedic treatment alone. Thirty infants aged 1 to 5 months with confirmed unilateral or bilateral DDH (Graf IIa to III) will be randomized to two parallel groups. The experimental group will receive one manual intervention session per week for three consecutive weeks in addition to conventional orthopedic treatment. The comparison group will receive conventional orthopedic treatment alone. Ultrasound assessments will be performed at baseline (T0) and after the intervention period (T1). In infants with bilateral DDH, both dysplastic hips will be evaluated at both time points and recorded separately. A secondary objective is to describe parental acceptability of the manual intervention and study procedures. As a pilot study, the project is intended to provide preliminary information on the direction and variability of the intervention effect, parental acceptability, and study feasibility to inform a future larger trial.",[27,28],"Developmental Dysplasia of the Hip (DDH)","Congenital Hip Dysplasia",[30,31,32,33,34],"Developmental dysplasia of the hip","Pilot study","manual therapy","coxal bone","infant","NOT_YET_RECRUITING","2026-08-05",{"date":38,"type":39},"2026-08-11","ACTUAL",{"date":41,"type":21},"2026-08",{"date":43,"type":21},"2027-09",{"name":45,"class":46},"Université de Sherbrooke","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":84},"100637695","computer-assisted-comparison-of-hip-socket-volume-and-surface-shape-after-pediatric-acetabular-osteotomies-100637695","NCT07581717","Computer-Assisted Comparison of Hip Socket Volume and Surface Shape After Pediatric Acetabular Osteotomies","Computer-Assisted Comparative Analysis of Acetabular Volume and Surface Morphology in Pediatric Acetabular Osteotomies (Salter, Dega, San Diego, and Pemberton)","PAVMS","Inclusion Criteria:\n\n1. Age 2 to 18 years\n2. Developmental dysplasia of the hip or residual acetabular dysplasia\n3. Primary Salter, Dega, San Diego, or Pemberton acetabular osteotomy planned at Istanbul University, Istanbul Faculty of Medicine\n4. Preoperative hip MRI available within 6 weeks before surgery\n5. Early postoperative hip MRI available 3 to 8 weeks after surgery\n6. MRI quality adequate for three-dimensional morphometric analysis\n7. Unilateral or bilateral cases eligible\n\nExclusion Criteria:\n\n1. Hip pathology not related to developmental dysplasia of the hip, including Perthes disease, slipped capital femoral epiphysis, neuromuscular dysplasia, or infection\u002Ftrauma sequelae\n2. Previous surgery on the same hip that significantly alters anatomy, including prior pelvic or femoral osteotomy or open reduction, or current metal implant\u002Ffusion\n3. MRI contraindication or safety issue, including MR-incompatible implant\u002Fdevice, severe claustrophobia, or a medical barrier to sedation\u002Fanesthesia\n4. MRI not compatible with protocol or inadequate for analysis","2 Years","18 Years",{"count":58,"type":21},12,"OBSERVATIONAL","The goal of this observational study is to learn how four acetabular osteotomy techniques change the shape of the hip socket in children and adolescents with developmental dysplasia of the hip or residual acetabular dysplasia.\n\nThe main questions it aims to answer are:\n\nHow do virtual Salter, Dega, San Diego, and Pemberton osteotomies differ in acetabular volume and surface shape on participant-specific three-dimensional models? How closely does the virtual result of the osteotomy actually performed match the early postoperative magnetic resonance imaging (MRI)?\n\nParticipants will have a three-dimensional pelvis-acetabulum model created from preoperative MRI. Researchers will perform virtual Salter, Dega, San Diego, and Pemberton osteotomies on that model and measure the resulting acetabular morphology. The virtual result of the osteotomy actually performed will then be compared with the participant's early postoperative MRI.",[27,62,63],"Developmental Dysplasia of the Hip","Acetabular Dysplasia",[65,66,67,68,30,69,70,71,72,73],"Salter osteotomy","Dega osteotomy","San Diego osteotomy","Pemberton osteotomy","Acetabular dysplasia","Magnetic resonance imaging","Three dimensional modeling","Acetabular morphometry","Methodological validation","RECRUITING","2026-06-24",{"date":77,"type":39},"2026-06-26",{"date":79,"type":39},"2026-05-10",{"date":81,"type":21},"2026-10-15",{"name":83,"class":46},"Istanbul University",1,{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":93,"sex":16,"minAge":94,"maxAge":95,"enrollmentInfo":96,"targetDuration":4,"studyType":22,"phases":98,"briefSummary":99,"conditions":100,"keywords":101,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":4},"100630483","evaluation-of-a-software-application-for-assessment-of-developmental-dysplasia-of-the-hip-100630483","NCT07488260","Evaluation of a Software Application for Assessment of Developmental Dysplasia of the Hip","Evaluation of the Concordance Between the Software Application and Standard Ultrasound Assessment in Classifying Hip Types in Infants Screened for Developmental Dysplasia of the Hip (DDH)","EPA-DDH","Inclusion Criteria:\n\n1. Participants whose Parent(s) or Legally Authorized Representative(s) have provided written informed consent;\n2. Participants who need to undergo routine DDH screening and receive an ultrasound as part of the clinical investigation;\n3. Participants of either sex aged between 4 weeks and 6 months weeks.\n\nExclusion Criteria:\n\n1. Participants with open wounds, ulcers, burns, viral or bacterial infections at the site intended for examination;\n2. Participants with significant anatomical abnormalities (e.g. cerebral palsy, joint contracture, suppurative coxitis, other hip or limb deformities, or teratological hip dysplasia) that may affect the feasibility or accuracy of the examination;\n3. Participants with history of trauma, surgical intervention, or post-traumatic\u002Fpost-surgical condition in the area to be examined.",true,"4 Weeks","6 Months",{"count":97,"type":21},150,[24],"The goal of this prospective, multicentre clinical investigation is to evaluate whether an artificial intelligence (AI)-supported software application can assist clinicians in the diagnostic assessment of developmental dysplasia of the hip (DDH) during routine ultrasound screening in infants.\n\nThe main questions it aims to answer are: Does the diagnostic classification generated by the application agree with the classification obtained by physicians using standard ultrasound examination according to the Graf method? Can the application reliably identify key anatomical landmarks and angles required for DDH assessment?\n\nResearchers will compare the AI-generated diagnostic results with those obtained from standard ultrasound examinations performed by physicians to evaluate the level of agreement between the two approaches.\n\nParticipants will:\n\nundergo a routine hip ultrasound examination performed by a physician according to the Graf method,\n\nhave ultrasound images analyzed by the application,\n\nhave the AI-generated results compared with the physician's assessment.",[27],[62,102,103,104,105],"DDH","Hip Ultrasound","Graf Method","Artificial Intelligence","2026-04-02",{"date":108,"type":39},"2026-04-08",{"date":110,"type":21},"2026-07",{"date":112,"type":21},"2027-01",{"name":114,"class":46},"Pentacomp Systemy Informatyczne S.A"]