[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"diabetes-complication\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:diabetes-complication":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,41,75],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100647021","effect-of-resisted-blood-flow-restriction-100647021",false,"NCT07685119","Effect of Resisted Blood Flow Restriction","Effect of Resisted Blood Flow Restriction on Balance and Physical Function in Patients With Type II Diabetes","BFR-DM2","Inclusion Criteria Diagnosed with type 2 diabetes mellitus (T2DM) for at least 5 years. Age between 50 and 60 years. medically stable and cleared for participation in a low-to-moderate intensity exercise program.\n\nNot currently engaged in structured resistance training. Able to walk independently without assistive devices. Berg Balance Scale (BBS) score between 21 and 40, indicating moderate balance impairment.\n\nExclusion Criteria History of recent cardiovascular events or uncontrolled hypertension. Peripheral arterial disease or deep vein thrombosis. Severe diabetic neuropathy or retinopathy. Musculoskeletal disorders affecting exercise performance. Cognitive impairments or psychiatric illness interfering with adherence to protocol.\n\nSmokers. Uncontrolled diabetes.","ALL","50 Years","60 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to investigate the effect of adding resisted blood flow restriction (BFR) training to a standard exercise program in adults aged 50-60 with Type 2 Diabetes Mellitus (T2DM). The main questions it aims to answer are:\n\nDoes adding BFR training significantly increase muscle strength compared to standard exercise alone? Does the BFR intervention lead to measurable improvements in balance and physical function? Researchers will compare a group performing standard therapeutic exercise combined with BFR to a control group performing the same exercise program without BFR to see if the BFR group achieves superior gains in strength and functional independence.\n\nParticipants will:\n\nComplete a 12-week supervised exercise program in an outpatient setting. Wear compression cuffs on their limbs during low-intensity resistance exercises (for the BFR group).\n\nUndergo assessments for muscle strength (via handheld dynamometry), balance, and functional mobility before and after the intervention.",[28],"Diabetes Complication","NOT_YET_RECRUITING","2026-07-02",{"date":32,"type":33},"2026-07-06","ACTUAL",{"date":35,"type":22},"2026-06-30",{"date":37,"type":22},"2026-12-01",{"name":39,"class":40},"Cairo University","OTHER",{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":23,"phases":53,"briefSummary":54,"conditions":55,"keywords":61,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":74},"100635561","effects-of-leg-ergometer-versus-arm-ergometer-on-blood-glucose-exercise-tolerance-weight-and-psychological-stress-among-gestational-diabetic-patients-100635561","NCT07554287","Effects of Leg Ergometer Versus Arm Ergometer on Blood Glucose, Exercise Tolerance, Weight, and Psychological Stress Among Gestational Diabetic Patients","GDM","Inclusion Criteria:\n\n1. Female participants aged 18-35 years.\n2. Gestational age 14-28 weeks (second trimester).\n3. Singleton pregnancy (confirmed by obstetric record) only to avoid complications of multiple gestation.\n4. Include both primigravida and multigravida (i.e., first or subsequent pregnancy).\n5. Women with first time GDM in pregnancy.\n6. Women with clinical diagnosis of gestational diabetes according to hospital\u002FWHO criteria or hospital diagnostic test.\n7. Blood glucose levels:\n\n   Random capillary glucose \\\u003C 200 mg\u002FdL at screening (to exclude overt diabetes)\n8. Blood pressure:\n\n   * Systolic BP \\\u003C 140 mmHg and Diastolic BP \\\u003C 90 mmHg (no confirmed gestational hypertension).\n   * If BP ≥140\u002F90 mmHg, confirm with repeat measurement 4 hours apart; exclude if persistent.\n9. Willingness to participate and provide written informed consent.\n10. Medically cleared by obstetrician to participate in moderate aerobic exercise.\n\nExclusion Criteria:\n\n1. Previous Cesarean section or medically indicated bed rest.\n2. Known pre-existing diabetes mellitus (Type 1 or Type 2 prior to pregnancy).\n3. Known major obstetric complications (e.g., placenta previa, severe pre- eclampsia).\n4. Patients having multiple\u002Ftwin\u002Ftriplet pregnancies.\n5. Known major fetal anomaly.\n6. Anemic women with Hb \\\u003C 9 g\u002FdL (excluded to prevent exercise intolerance).\n7. Uncontrolled cardiovascular disease, musculoskeletal, or medical contraindications to exercise.\n8. Psychiatric conditions severe enough to hinder informed consent.\n9. Any other medical condition that, in the opinion of the obstetrician, makes participation unsafe.","FEMALE","18 Years","35 Years",{"count":52,"type":22},108,[25],"The current study is a single-blind, parallel-group randomized controlled trial involving 108 participants with diabetes during pregnancy. The trial will compare leg ergometer with arm ergometer. Interventions will be delivered three times per week for eight weeks. The primary outcomes are glucose, exercise tolerance, weight, and psychological stress. Assessments will be conducted at baseline and after eight weeks. The trial will be carried out at Jinnah hospital, Services hospital, Sir Ganga Ram Hospital, Lahore. The hypothesis is that the leg ergometer including aerobic exercise will result in greater reduction in glucose and exercise tolerance, weight and stress management than arm ergometer.",[56,57,58,59,28,60],"Diabetes During Pregnancy","Pregnancy Complications","Pregnancy in Diabetes","Gestational Diabetes Mellitus (GDM)","Gestational",[62,63,46,60],"gestational diabetes","diabetes in pregnancy","RECRUITING","2026-06-16",{"date":67,"type":33},"2026-06-18",{"date":69,"type":33},"2026-05-26",{"date":71,"type":22},"2026-10-15",{"name":73,"class":40},"Lahore University of Biological and Applied Sciences",1,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":82,"sex":17,"minAge":49,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":85,"phases":4,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":74},"100611514","evaluation-of-perioperative-myocardial-injury-in-patients-undergoing-below-knee-lower-extremity-surgery-100611514","NCT07241572","Evaluation of Perioperative Myocardial Injury in Patients Undergoing Below-Knee Lower Extremity Surgery","Evaluation of Perioperative Myocardial Injury in Patients Undergoing Below-knee Lower Extremity Surgery With Peripheral Nerve Block","Inclusion Criteria:\n\n* Patients over 18 years of age\n* Patients undergoing below-knee lower extremity surgery\n* Patients with ASA classifications I, II, III, and IV\n* Patients who have consented before the procedure\n* Patients who are literate and able to give consent\n\nExclusion Criteria:\n\n* Patients in whom regional anesthesia is contraindicated\n* Patients who refuse to participate in the study",true,{"count":84,"type":22},54,"OBSERVATIONAL","The aim of this observational study was to detect myocardial damage by monitoring high-sensitive troponin I levels in patients undergoing below-knee extremity surgery with peripheral nerve block.\n\nThe primary question it aims to answer is:\n\nHow effective are peroperative high-sensitive troponin I levels in predicting myocardial damage?\n\nHigh-sensitive troponin I levels will be monitored intraoperatively and at 24 and 48 hours postoperatively.",[88,28],"Myocardial Ischemia",[90,91,92,93],"myocardial injury","Troponın I","diabetic neuropaty","MINS","2025-11-24",{"date":96,"type":33},"2025-12-01",{"date":98,"type":33},"2025-09-01",{"date":100,"type":22},"2026-01-10",{"name":102,"class":40},"Ankara City Hospital Bilkent"]