[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"difficult-intravenous-access\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:difficult-intravenous-access":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,59,93],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":36,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":58},"100652838","single-lumen-midline-catheter-vs-ultrasound-guided-peripheral-iv-as-performed-by-bedside-emergency-department-registered-nurses-100652838",false,"NCT07779317","Single Lumen Midline Catheter vs Ultrasound Guided Peripheral IV as Performed by Bedside Emergency Department Registered Nurses","Superior Venous Access: Single Lumen Midline Catheter vs Ultrasound Guided Peripheral IV as Performed by Bedside Emergency Department Registered Nurses, A Randomized Clinical Trial","SUMMIT","Inclusion Criteria:\n\n* Adults 18 years of age or older\n* Presenting to the Albany Medical Center Emergency Department\n* Require intravenous access\n* Have difficult intravenous access (DIVA) defined by at least one of the following:\n* Two failed attempts at landmark-based or ultrasound-guided peripheral vascular access performed by qualified emergency department staff\n* A history of or active comorbid condition associated with difficult intravenous access, including:\n* Implanted vascular access port (current or previous)\n* End-stage renal disease with dialysis fistula\n* Sickle cell disease\n* Current or previous intravenous drug use\n* Self-reported difficult intravenous access plus one of the following:\n* A history of requiring two or more IV attempts during a previous healthcare encounter (self-reported or documented in the medical record)\n* A previous requirement for a rescue vascular access device after failed IV access, including:\n* Ultrasound-guided peripheral IV\n* Midline catheter\n* Peripherally inserted central catheter (PICC)\n* Central venous catheter (CVC)\n* Intraosseous catheter\n\nExclusion Criteria:\n\n* Younger than 18 years of age\n* Prisoners\n* Non-English-proficient patients\n* Patients in whom the device cannot be adequately stabilized because of tissue injury or treatment involving the available extremities (including burns, complex humeral fractures, or dialysis fistulas)\n* Patients who lack the capacity to provide informed consent and do not have an authorized legal representative available\n* Patients without an identifiable target vein on ultrasonography\n* Patients known to be pregnant\n* Previous enrollment in the study\n* Previous withdrawal from the study\n* Presentation during a period when no study proceduralists are available\n* Patients for whom the informed consent and enrollment process could delay time-sensitive medical care","ALL","18 Years",{"count":20,"type":21},292,"ESTIMATED","INTERVENTIONAL",[24],"NA","Obtaining intravenous (IV) access is one of the most common procedures performed in the emergency department (ED). IV access is necessary for many aspects of patient care, including blood tests, administration of medications and intravenous fluids, and diagnostic imaging. However, some patients have difficult intravenous access (DIVA), making it challenging to successfully place an IV catheter. Difficulty obtaining IV access can lead to delays in diagnosis and treatment, prolonged emergency department stays, multiple needle punctures, and increased patient discomfort.\n\nSeveral specialized IV devices are available for patients with DIVA. Two commonly used ultrasound-guided devices are long peripheral intravenous catheters and single-lumen midline catheters. Both devices are inserted into veins using ultrasound guidance, but they differ in catheter length and expected duration of use. Long peripheral IV catheters are commonly used in emergency departments but may fail relatively quickly. Midline catheters may remain functional for longer periods and may reduce the need for additional IV insertions during a patient's hospital stay. However, these devices have traditionally been inserted by specialized clinicians, such as members of vascular access teams, rather than by bedside emergency department nurses, who perform most vascular access procedures in many emergency departments.\n\nThe purpose of this study is to compare ultrasound-guided single-lumen midline catheters with ultrasound-guided long peripheral IV catheters when both procedures are performed by specially trained bedside emergency department nurses. The study will evaluate whether midline catheters can be inserted as successfully and as safely as long peripheral IV catheters in adult emergency department patients with difficult intravenous access.\n\nParticipants will be randomly assigned to receive either an ultrasound-guided single-lumen midline catheter or an ultrasound-guided long peripheral IV catheter. Researchers will compare the two devices by measuring procedural success, catheter-related complications, catheter dwell time, completion of care using the original device, and patient satisfaction.\n\nThe results of this study may help determine whether bedside emergency department nurses with training and experience in ultrasound-guided vascular access can successfully use single-lumen midline catheters in routine clinical practice. The study will also evaluate which vascular access device provides the best balance of safety, reliability, and patient experience for emergency department patients with difficult intravenous access. This information may help guide future recommendations for vascular access device selection in the emergency department.",[27,28,29,30,31,32,33,34,35],"Difficult Vein Access","Emergency Department Patients","Nurses Role","Midline Catheter","Ultrasound Assistance","Difficult Intravenous Access","Catheterization, Peripheral","Catheterization","Emergency Service, Hospital",[37,38,30,39,40,41,42,43,44,45],"DIVA","Ultrasound-Guided Vascular Access","Single-Lumen Midline Catheter","Long Peripheral Intravenous Catheter","Ultrasound-Guided Peripheral Intravenous Catheter","Emergency Department Nursing","Emergency Nursing","Vascular Access Device","Ultrasound-Guided Intravenous Access","RECRUITING","2026-08-18",{"date":49,"type":50},"2026-08-21","ACTUAL",{"date":52,"type":50},"2026-08-11",{"date":54,"type":21},"2027-03",{"name":56,"class":57},"Albany Medical College","OTHER",1,{"id":60,"slug":61,"hasResults":11,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":4,"eligibilityCriteria":65,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":66,"targetDuration":4,"studyType":22,"phases":68,"briefSummary":69,"conditions":70,"keywords":73,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":58},"100567482","single-lumen-midline-catheter-vs-long-peripheral-intravenous-cather-for-difficult-intravenous-access-in-the-ed-100567482","NCT06668766","Single Lumen Midline Catheter vs Long Peripheral Intravenous Cather for Difficult Intravenous Access in the ED","Superior Ultrasound-Guided Venous Access: Single-Lumen Midline Catheters vs Long Peripheral IVs for Difficult IV Access in the Emergency Department, A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adult (age 18 and older) patients presenting to the AMC ED with difficult IV access defined as any of the following:\n\n  * Two failed attempts at landmark based IV or US-guided peripheral vascular access by qualified ED staff\n  * Self-reported history of difficult IV access and one of the following:\n\n    * History of requiring 2 or more IV attempts on a previous visit (either self-reported or documented in the electronic medical record)\n    * Previous requirement for a rescue device after failed IV access attempt. These devices are as follows:\n* US guided PIV\n* Midline catheter\n* Peripherally inserted central catheter\n* Central venous catheter\n* Intraosseous catheter\n* History of or active comorbid disease state with known difficult IV access\n* Prior or current implanted port device\n* End stage renal disease with fistula\n* Sickle cell disease\n* History of or active intravenous drug use\n\nExclusion Criteria:\n\n* Patients under the age of 18\n* Known Prisoners\n* Non-English-speaking patients\n* Patients in whom the device cannot be stabilized due to tissue or treatments in bilateral extremities or available extremity (burns, complex humeral fractures, dialysis fistulas etc.)\n* Patients lacking capacity to consent\n* Patients unable to sign written consent\n* Patients without identifiable target veins by ultrasonography\n* Known pregnant patients\n* Previously enrolled in this study\n* Previously withdrawn from this study\n* Presented when no study IV proceduralists are available\n* Patients in whom obtaining informed consent and being enrolled in the study would put them at risk for obtaining time sensitive medical care",{"count":67,"type":21},270,[24],"Many patients in the emergency department have veins that are difficult to get an intrevenous (IV) catheter into (called \"difficult IV access\"). These patients may require other methods to obtain access to a vein for administration of the necessary medications. The 2-inch long IV is most commonly used in emergency departments for people with difficulty IV access. Typically, a healthcare worker will use an ultrasound to help to see the veins underneath the skin while inserting the IV into the vein. That is, the ultrasound helps the healthcare worker visualize veins that are deeper in the arm and may not be felt through the skin. Another device that can be used is a 4-inch midline catheter. This device is less commonly used as many emergency departments do not have participants available, but it serves the same purpose as the 2-inch long IVs (that is, to give medicine into the vein and sometimes to take blood). A 4-inch midline catheter is similar to a 2-inch long IV, but has a few differences. First, the 4-inch midline catheter is even longer than the 2-inch long IV. The 4-inch midline catheter is 10-cm (about 4-inches or the size of 4 quarters side-by-side), while the 2-inch long IV is 4.78-cm (nearly 2-inches or two quarters side-by-side). Second, the 4-inch midline catheter is inserted into using a guidewire to help move the catheter in the vein (similar in concept to a train moving along a track), while the 2-inch long IV does not have this guidewire. The guidewire does not hurt and most do not know it is being used. It is just an additional step to help guide the catheter in the vein. The investigators are conducting this research study to determine which catheter is better for patients with difficult IV access: the 4-inch midline catheter or the 2-inch long IV.",[32,30,71,72],"Peripheral Intravenous Catheter","Emergency Department Patient",[74,75,76,77,78,79,80,81,82,83,84],"midline catheter","difficult intravenous access","difficult IV access","USGIV","long peripheral IV","peripheral IV","peripheral intravenous catheter","Emergency department","emergency medicine","single lumen midline catheter","long peripheral intravenous catheter","2026-01-16",{"date":87,"type":50},"2026-01-20",{"date":89,"type":50},"2025-01-01",{"date":91,"type":21},"2027-10-21",{"name":56,"class":57},{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":99,"eligibilityCriteria":100,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":101,"targetDuration":4,"studyType":22,"phases":103,"briefSummary":104,"conditions":105,"keywords":107,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":58},"100593351","ultra-long-peripheral-catheter-versus-accelerated-seldinger-technique-long-peripheral-catheter-in-difficult-iv-access-patients-100593351","NCT07005310","Ultra-Long Peripheral Catheter Versus Accelerated Seldinger Technique Long Peripheral Catheter in Difficult IV Access Patients","Ultra Long Peripheral Catheter Versus Accelerated Seldinger Technique Long Peripheral Catheter in Difficult Intravenous Access Patients: a Pragmatic Randomised Controlled Trial","ULAST","Inclusion Criteria:\n\n* Adult inpatients with DIVA, requiring placement of a long peripheral catheter, will be included in the study.\n* A digital request form for venous access must be completed by the treating physician at the ward.\n* Patients must be proficient in either Dutch or French\n* Patients must have decision-making capacity or be represented by a legal representative.\n\nExclusion Criteria:\n\n* Expected therapy duration of less than 24 hours\n* pregnancy\n* Need for central venous access\n* Inability to locate a deep peripheral vein in the upper extremity prior enrollment in the study\n* Veins located deeper than 1.6cm prior enrollment in the study\n* withdrawal of consent, or presentation at a time when study personnel are unavailable.",{"count":102,"type":21},100,[24],"The aim of this study is to perform a comparative analysis of clinical outcomes associated with the use of an ultra-long peripheral catheter using (catheter-over-the-needle technique) versus an AST-long peripheral catheter in adult patients with difficult intravenous access (DIVA) in a real-world clinical setting. Specifically, the study will assess potential benefits, including longer mean catheter dwell time and improved catheter usability, as well as potential harms, such as increased incidence of catheter-related thrombosis, infections, phlebitis, infiltration, and unplanned catheter removal.",[32,106],"Adults",[108,109,110,111,112],"Long peripheral catheter","Accelerated seldinger technique","Pragmatic randomized controlled trial","Dwell time","complications","NOT_YET_RECRUITING","2025-06-02",{"date":116,"type":50},"2025-06-05",{"date":118,"type":21},"2025-07-01",{"date":120,"type":21},"2026-04-30",{"name":122,"class":57},"University Ghent"]