[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"disclosure\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:disclosure":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,78],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":31,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100649105","one-page-truth-telling-aid-for-cancer-disclosure-100649105",false,"NCT07730164","One-Page Truth-Telling Aid for Cancer Disclosure","A One-Page Truth-Telling Aid for Cancer Disclosure in Taiwan: A Two-Arm Pragmatic Randomized Controlled Trial","【Physicians】\n\n* Inclusion Criteria:\n\n  * Physicians who provide clinical care for patients with cancer in participating outpatient departments.\n  * Physicians who are involved in cancer-related truth-telling or disclosure consultations.\n  * Physicians who are willing to participate and provide informed consent.\n* Exclusion Criteria:\n\n  * Physicians who are unable or unwilling to complete study procedures or follow-up assessments.\n\n【Patients】\n\n* Inclusion Criteria:\n\n  * Patients diagnosed with cancer.\n  * Patients who are scheduled to receive cancer-related information from a participating physician, including information about diagnosis, recurrence, metastasis, end-of-life status.\n  * Patients who are able to communicate in Mandarin Chinese or Taiwanese.\n  * Patients who are able to complete questionnaires independently or with assistance from the research assistant.\n  * Patients who are willing to participate and provide informed consent.\n* Exclusion Criteria:\n\n  * Patients who are unable to provide informed consent.\n  * Patients with severe cognitive impairment, severe physical illness, or emotional distress that prevents participation, as judged by the clinical team or research staff.\n  * Patients who are unable to complete the study questionnaires even with assistance.","ALL",{"count":18,"type":19},400,"ESTIMATED","INTERVENTIONAL",[22],"NA","The goal of this clinical trial is to learn whether a one-page communication aid can improve communication between physicians and patients with cancer during cancer-related truth-telling consultations. The one-page aid is designed to help physicians quickly understand patients' preferences and needs before the consultation.\n\nThe main questions it aims to answer are:\n\n* Does the one-page communication aid improve patients' satisfaction with how cancer-related information is explained?\n* Does the one-page communication aid reduce patients' emotional distress after the consultation?\n* Does the one-page communication aid improve physicians' confidence in communicating cancer-related information?\n\nResearchers will compare patients whose physicians receive the one-page communication aid with patients whose physicians provide usual care with a blank sheet for patients to write down questions. This comparison will help determine whether the one-page aid improves communication, emotional outcomes, and physician confidence.\n\nParticipants will:\n\n* Complete questionnaires before and after the consultation\n* Receive either the one-page communication aid or a blank sheet, depending on their physician's group\n* Complete follow-up questionnaires at 3 months and 6 months after the consultation\n\nPhysicians will also complete brief questionnaires about their communication confidence at baseline, 1 week after recruitment of their first enrolled patient, 3 months, and 6 months.",[25,26,27,28,29,30],"Neoplams","Physician-Patient Relations","Communication Research","Disclosure","Communication About Health Information","Preference, Patient",[32],"Cancer truth-telling; disclosure preferences; physician-patient communication; communication aid; oncology care; psychooncology","RECRUITING","2026-07-22",{"date":36,"type":37},"2026-07-28","ACTUAL",{"date":39,"type":37},"2025-11-27",{"date":41,"type":19},"2027-07",{"name":43,"class":44},"Chang Gung University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":45},"100616277","ai-driven-consent-simplification-study-100616277","NCT07303517","AI-Driven Consent Simplification Study","ACCESS: AI-Driven Consent Simplification Study","ACCESS","Inclusion Criteria:\n\nGroup 1:\n\n* Age 60 years and above\n* UCLA patient\n* English speaking\n* Ability to provide informed consent\n\nGroup 2:\n\n* UCLA investigators who are health providers that perform clinical trials\n* Must be clinical research investigatory and staff actively involved in research operations at UCLA\n* English speaking\n\nGroup 3:\n\n* Individuals involved in IRB activities (chairs, committee members, staff)\n* Must be a director or staff at UCLA\n* English speaking\n\nExclusion Criteria:\n\n* Group 1: None\n* Group 2: PI and co-PIs of the study \"Donor Chimerism and Graft Survival Following Combined HLA-Identical Sibling Living Donor Kidney and Hematopoietic Stem Cell Transplantation Utilizing a Conditioning Regimen of Total Lymphoid Irradiation (TLI) and Rabbit Anti-Thymocyte Globulin (rATG)\"\n* Group 3: Individuals from the IRB who have reviewed the study submission for \"Donor Chimerism and Graft Survival Following Combined HLA-Identical Sibling Living Donor Kidney and Hematopoietic Stem Cell Transplantation Utilizing a Conditioning Regimen of Total Lymphoid Irradiation (TLI) and Rabbit Anti-Thymocyte Globulin (rATG)\"",true,"18 Years",{"count":57,"type":19},230,"OBSERVATIONAL","The overarching goal of this pilot is to explore how generative artificial intelligence (genAI) can be used to improve the accessibility and understandability of informed consent materials in clinical research. The study will test the extent to which informed consent text can be improved by large language models (LLM; specifically, ChatGPT and NotebookLM) along with other AI tools (specifically, ElevenLabs) through qualitative and quantitative analyses.\n\nSimplifying such forms using genAI may facilitate better comprehension, ensuring truly informed consent. Improving informed consent form (ICF) comprehension can lead to more informed and willing participation in clinical studies. This improved understanding may result in higher enrollment rates, better subject retention, and more accurate data collection as individuals will have a clearer understanding of study procedures and risks.",[61,62,63,28],"Informed Consent","Comprehension","Communication",[65,66,67,68],"Informed Consent Readability","Plain language","Simplified consent forms","Research ethics","2026-05-04",{"date":71,"type":37},"2026-05-08",{"date":73,"type":37},"2026-01-08",{"date":75,"type":19},"2026-12-01",{"name":77,"class":44},"University of California, Los Angeles",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":20,"phases":89,"briefSummary":90,"conditions":91,"keywords":94,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":106},"100545657","honest-open-proud-for-psychotic-and-bipolar-disorder-in-norway-100545657","NCT06384755","Honest Open Proud for Psychotic and Bipolar Disorder in Norway","Evaluation of a Norwegian Adaptation of the Honest Open Proud Program for Adults With Psychotic and Bipolar Disorders in an Outpatient Setting","HOP-NOR","Inclusion Criteria:\n\n* Diagnosed current psychotic (F 20) or bipolar disorder (F 30) according to International Classification of Diseases 10th Revision (ICD-10)\n* Age 18 to 65\n* Ability to provide written informed consent.\n* Fluent in Norwegian (needed for self-report measures)\n* Experience difficulties with stigma and disclosure regarding mental illness.\n\nExclusion Criteria:\n\n* Intellectual disability\n* Organic disorders","65 Years",{"count":88,"type":19},40,[22],"The purpose of this pilot study is to evaluate the feasibility, acceptability and efficacy of a Norwegian adaptation of the group-based intervention 'Honest Open Proud' among adults with psychotic and bipolar disorders in an outpatient setting.",[92,93,28],"Psychotic Disorders","Bipolar Disorder",[95,96],"Honest Open Proud program","Psychotic and Bipolar disorders","2024-04-30",{"date":99,"type":37},"2024-05-02",{"date":101,"type":37},"2024-04-20",{"date":103,"type":19},"2026-12-31",{"name":105,"class":44},"Oslo University Hospital",2]