[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"early-intervention\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:early-intervention":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,49,83],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100652928","vipeeragent-for-adolescent-mental-health-a-three-arm-parallel-randomized-controlled-trial-100652928",false,"NCT07778758","VIPeerAgent for Adolescent Mental Health: A Three-Arm Parallel Randomized Controlled Trial","Efficacy of VIPeerAgent for Mental Health Intervention in Adolescents: A Three-Arm Parallel Randomized Controlled Trial With Non-Inferiority and Superiority Testing","Inclusion Criteria:\n\n* Adolescents and young adults aged 14-25 years. Experienced at least one moderate stressful life event within the past 6 months, with a score of moderate level or above on one or more items of the Stressful Life Events Scale.\n\nAble to read and communicate in Chinese. Willing to actively participate in the study and provide written informed consent.\n\nA Brief Symptom Inventory-53 (BSI-53) score \\\u003C 63, indicating the absence of a clinically diagnosed psychological disorder.\n\nExclusion Criteria:\n\n* A history of clinically diagnosed severe mental or psychiatric disorders, such as major depressive disorder or schizophrenia.\n\nPresence of suicidal ideation within the past 6 months or current suicidal ideation.\n\nReceipt of professional psychological treatment within the past 12 months.","ALL","14 Years","25 Years",{"count":20,"type":21},234,"ESTIMATED","INTERVENTIONAL",[24],"NA","This three-arm parallel randomized controlled trial aims to evaluate the effectiveness of VIPeerAgent, a virtual peer support agent, in improving mental health outcomes among adolescents and young adults aged 14-25 years experiencing psychological distress without a diagnosed mental disorder. Participants will be randomized to receive support from VIPeerAgent, a human peer mentor, or usual care. The study will assess whether VIPeerAgent is non-inferior to human peer support and superior to usual care in promoting mental health. Outcomes include mental health status, psychological resilience, coping strategies, perceived social support, and emotional intelligence. The findings will provide evidence for the effectiveness and scalability of AI-assisted peer support as an early intervention approach for youth mental health.",[27,28,29],"Youth Mental Health","Psychological Distress in Adolescents and Young Adults","Early Intervention",[31,32,33,34,35],"mental health","Agent","Randomized Controlled Trial","adolescence","youth","NOT_YET_RECRUITING","2026-08-18",{"date":39,"type":40},"2026-08-21","ACTUAL",{"date":42,"type":21},"2026-08-20",{"date":44,"type":21},"2026-12-10",{"name":46,"class":47},"Sun Yat-sen University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":67,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":5},"100609900","implementing-powered-mobility-in-early-childhood-settings-for-children-with-cerebral-palsy-100609900","NCT07220590","Implementing Powered Mobility in Early Childhood Settings for Children With Cerebral Palsy","Bridging the Gap: Implementing A Powered Mobility Intervention Into Early Childhood Settings for Young Children With Cerebral Palsy (GMFCS IV-V)","Inclusion Criteria:\n\nChildren:\n\n1. Diagnosis of cerebral palsy or similar motor impairment\n2. Gross Motor Function Classification System (GMFCS) Levels IV-V\n3. Age 12 to 32 months at enrollment\n4. Enrolled in early intervention services\n\nCaregivers:\n\n1. Parent or legal guardian of an enrolled child participant\n2. Age 18 years or older\n3. English- or Spanish-speaking\n4. Able and willing to participate in home-based data collection, including caregiver coaching sessions, completion of surveys, and video-recorded sessions\n5. Able to provide informed consent\n\nTherapists:\n\n1. Licensed physical therapist or occupational therapist\n2. Employed at participating early intervention or early childhood special education settings\n3. Provide services to children with cerebral palsy or motor delays\n4. No prior powered mobility intervention training required\n5. Willing to complete powered mobility implementation training and participate in study assessments\n\nExclusion Criteria:\n\n1. Inability or unwillingness to provide informed consent\n2. Inability to complete required study procedures","12 Months",{"count":58,"type":21},70,[24],"The goal of this clinical trial is to learn if a therapist training program can help providers in Part C Early Childhood Settings use powered mobility (PM) with young children who have cerebral palsy (Gross Motor Function Classification System Levels IV-V). The study will also look at whether this training is practical and useful for therapists, families, and children.\n\nThe main questions it aims to answer are:\n\n1. Can therapists successfully use the training to provide powered mobility interventions in home and early childhood settings?\n2. Do families and children find the intervention acceptable and helpful?\n3. What benefits do children show in mobility, participation, and engagement after using powered mobility?\n\nIn this study, therapists and families will:\n\n1. Take part in a training program about how to use powered mobility with young children\n2. Use powered mobility devices (Permobil Explorer Mini) with children during everyday routines\n3. Complete surveys, interviews, and observations about their experiences",[62,63,64,65,29,66],"Cerebral Palsy Children","Motor Disabilities","Developmental Disability","Rehabilitation","Assistive Technology",[68,69,70,71,72],"Power Mobility","Implementation Science","Community-engaged research","Caregiver coaching","Pediatric Rehabilitation","RECRUITING","2026-07-02",{"date":76,"type":40},"2026-07-06",{"date":78,"type":40},"2025-10-01",{"date":80,"type":21},"2029-06-30",{"name":82,"class":47},"Oregon Health and Science University",{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":16,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":4,"studyType":22,"phases":95,"briefSummary":96,"conditions":97,"keywords":100,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":5},"100463781","the-effect-of-the-movement-imitation-therapy-in-preterm-mit-pb-in-motor-behaviors-quality-100463781","NCT05319158","The Effect of the Movement Imitation Therapy in Preterm (MIT-PB) in Motor Behavior's Quality.","The Effect of the Movement Imitation Therapy for Preterm Babies (MIT-PB) on Motor Behavior Quality. Quasi-experimental Design.","MIT-PB","Inclusion Criteria:\n\n* Preterm infants born before 32w GA and less than 1500g weight.\n* Infants who show Abnormal General Movements (CS-PR pattern) at 34-36w postmenstrual age (PMA).\n* Families able to understand\u002Fspeak Catalan, Spanish or English.\n* Families willing to participate who have the informed consent\n\nExclusion Criteria:\n\n* Infants with congenital abnormalities and\u002For genetic disorders\n* Infants with invasive ventilation or Continuous Positive Airway Pressure (CPAP) at 36 weeks PMA.\n* Infants with Normal General Movements at 34-36 w PMA.\n* Families not willing to participate.","22 Weeks","32 Weeks",{"count":94,"type":21},36,[24],"This study aims to assess the effect of a parent-administered intervention program based on MIT-PB in preterm with abnormal general movements during the preterm period. We will describe the short and long-term differences between infants exposed to MIT-PB and infants who follow current standard care.",[98,99,29],"Premature Birth","Risk",[101,102,103,104],"neonatal therapy","general movements","high risk neurodevelopment","physiotherapy","2024-12-05",{"date":107,"type":40},"2024-12-10",{"date":109,"type":40},"2022-04-04",{"date":111,"type":21},"2027-03-31",{"name":113,"class":47},"Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta"]