[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"edentulism-complete\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:edentulism-complete":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100648577","comparison-of-non-calibrated-splinting-bodies-and-t-marker-for-complete-arch-implant-scanning-100648577",false,"NCT07723404","Comparison of Non-Calibrated Splinting Bodies and T-Marker for Complete-Arch Implant Scanning","Accuracy of Complete-Arch Implant Scans Obtained Using Non-Calibrated Splinting Bodies and a Mobile Phone-Based Photogrammetry System (T-Marker): A Randomized Crossover Clinical Trial","Inclusion Criteria\n\n* Adults aged 18 years or older.\n* Completely edentulous maxilla rehabilitated with four well-integrated implants connected to multiunit abutments.\n* Patients presenting with a screw-retained interim implant-supported prosthesis or requiring a definitive implant-supported prosthesis.\n* Adequate implant osseointegration with no clinical signs of implant failure.\n* Ability to understand the study procedures and provide written informed consent.\n\nExclusion Criteria\n\n* Fewer than four implants supporting the maxillary prosthesis.\n* Implants located outside the maxillary arch.\n* Failed implants or implants exhibiting mobility.\n* Active peri-implant infection or suppuration.\n* Inability to tolerate intraoral scanning or comply with study procedures.\n* Refusal or inability to provide written informed consent.","ALL","20 Years","60 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized crossover clinical trial aims to compare the accuracy and scanning efficiency of two digital techniques for recording implant positions in completely edentulous patients receiving implant-supported full-arch prostheses. Each participant will undergo digital impressions using both a non-calibrated splinting scan body system (IoConnect) with an intraoral scanner and a mobile phone-based photogrammetry system (T-Marker). The order of the two scanning methods will be randomized.\n\nThe primary outcome is the accuracy (trueness) of implant position recording, assessed by comparing each digital impression with a verified reference model. Secondary outcomes include the time required to complete each digital impression. The findings of this study may help determine whether these digital workflows provide accurate and efficient alternatives for complete-arch implant impressions, thereby supporting clinical decision-making in implant prosthodontics.",[27,28],"Edentulism","Edentulism Complete","RECRUITING","2026-07-22",{"date":32,"type":33},"2026-07-23","ACTUAL",{"date":35,"type":33},"2026-04-01",{"date":37,"type":21},"2027-01-01",{"name":39,"class":40},"Menoufia University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":52,"conditions":53,"keywords":56,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":68,"leadSponsor":70,"locationsCount":41},"100646307","nutritional-intervention-for-older-adults-with-complete-dentures-100646307","NCT07692828","Nutritional Intervention for Older Adults With Complete Dentures","Novel Dietary Guidelines for Elderly Denture-wearers to Ensure Adequate Nutritional Intake, Good Quality of Life and Enhanced Performance on Cognitive Tasks","Inclusion Criteria:\n\n* Men and women aged 60 to 80 years.\n* Systemically healthy individuals or those with controlled chronic systemic conditions under regular medical supervision.\n* Functionally independent individuals, or those with a dedicated family member or caregiver available to provide support throughout the study period.\n* Wearers of both maxillary and mandibular complete removable dentures.\n* Adequate stability, retention, and functionality of both complete dentures allowing the participant to chew effectively during daily meals (accepting minor retention or stability limitations in the mandibular prosthesis, provided routine functional mastication is maintained).\n* Acceptable centric occlusion and jaw relationship allowing functional mastication.\n* Intact oral mucosa without active lesions or severe soreness in the denture-bearing areas.\n\nExclusion Criteria:\n\n* Altered salivary flow (hyposalivation or xerostomia) identified via anamnesis and sialometry, with an unstimulated salivary flow rate \\\u003C 0.1 mL\u002Fmin or a stimulated salivary flow rate \\\u003C 0.5 mL\u002Fmin.\n* Active oral mucosa diseases or lesions (e.g., cheilitis, denture stomatitis, ulcers, or aphthae) verified through intraoral examination.\n* Diagnosis of a major neurocognitive disorder by a qualified professional, verified via medical records and\u002For caregiver interview.\n* Color blindness (daltonism or color vision deficiency).\n* Presence of signs or symptoms of temporomandibular disorders (TMD).\n* Known history of allergy to peanuts or latex.\n* Underweight or severe undernutrition, defined as a Body Mass Index (BMI) \\\u003C 18.5 kg\u002Fm².","80 Years",{"count":20,"type":21},[24],"The purpose of this clinical trial is to test a nutritional intervention. This study helps older adults who wear complete removable dentures improve their health.\n\nThe main questions the study aims to answer are:\n\n* What are the participants life experiences living with complete dentures before the intervention?\n* Does the intervention improve the diet quality of the participants?\n* Does the intervention improve nutritional status of the participants?\n* Does the intervention improve chewing performance and muscle strength?\n* Does the intervention increase the thickness of the masticatory muscles?\n* Does the intervention improve stress and muscle health markers in saliva?\n* Does the intervention improve cognitive performance and oral health-related quality of life?\n* Does the intervention improve cerebral blood flow? The study will include a total of 40 participants, who will be assigned to two groups. One group of 20 participants will receive the nutritional intervention, while the other group of 20 participants will maintain their usual diet during the study period. This comparison will allow the investigators to assess the effectiveness of the intervention.\n\nParticipants will:\n\n* Take part in a personal interview about their life experience with dentures.\n* Follow a dietary guide with recommendations on specific food textures for six months.\n* Receive personalized nutritional counseling and participate in healthy cooking workshops.\n* Use a custom-built mobile application to access the educational content of the nutritional guide, view instructional videos uploaded biweekly, and receive automated reminder notifications.\n* Attend clinical follow-up assessments, including chewing performance, muscle assessment, saliva markers, assessment of diet quality and nutritional status, cognitive tests, and oral health-related quality of life.\n* Complete these assessments at three main time points: baseline, 3 months, and 6 months.",[28,54,55],"Denture, Complete","Mastication Disorder",[57,58,59,60,61,62],"Nutritional Intervention","Older Adults","Salivary Biomarkers","Cognitive Performance","OHRQoL","Masticatory Performance","NOT_YET_RECRUITING","2026-07-07",{"date":66,"type":33},"2026-07-09",{"date":66,"type":21},{"date":69,"type":21},"2028-05-12",{"name":71,"class":40},"Universidad de La Frontera",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":80,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":83,"briefSummary":84,"conditions":85,"keywords":86,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":4},"100640713","printow-occlusal-wear-of-denture-teeth-in-digitally-fabricated-complete-dentures-100640713","NCT07585162","PRINTOW: Occlusal Wear of Denture Teeth in Digitally Fabricated Complete Dentures","A Randomized, Double-Blind, Three-Arm Superiority Trial Comparing Occlusal Wear of 3D-Printed, CAD\u002FCAM-Milled, and Prefabricated Denture Teeth in Digitally Fabricated Complete Dentures in Edentulous Patients","Printow","Inclusion Criteria:\n\n* Written informed consent provided by the participant\n* Age ≥ 18 years\n* Fully edentulous maxilla and mandible requiring rehabilitation with new complete removable dental prostheses\n* Patients with or without mandibular implants (implant overdenture or conventional denture)\n* Clinical indication for fabrication of new maxillary and mandibular complete removable dental prostheses\n* Currently wearing complete dentures, or a maxillary denture combined with a mandibular denture or overdenture\n* Ability and willingness to attend all scheduled follow-up visits for the duration of the study\n\nExclusion Criteria:\n\n* Contraindications to the medical devices used, e.g. known hypersensitivity or allergy;\n* Known or suspected non-compliance, drug or alcohol abuse; Inability to follow the procedures of the investigation;\n* Enrolment of the investigator, his\u002Fher family members, employees and other dependent persons;\n* Reported severe bruxism or clenching habits, identified through patient interview and clinical examination, including self-reported grinding or clenching, partner reports, morning jaw discomfort, and other signs of parafunctional activity;\n* Width of the edentulous maxilla \\>80 mm;\n* Width of the edentulous mandible \\>80 mm; Vertical prosthetic space \\\u003C38 mm (maxilla or mandible);\n* Depression: Geriatric Depression Scale \\>9;\n* Xerostomia: UFR ≤ 0.2ml\u002F2min;\n* Dementia: Clock-Drawing Test ≤5;\n* Active peri-implant disease or instability of the two mandibular implants at baseline when implants are present;\n* Presence of an implant-retained prosthesis in the maxilla;\n* Planned implant-related surgical intervention during the study period.","18 Years",{"count":82,"type":21},45,[24],"This randomized controlled trial evaluates the occlusal wear of denture teeth fabricated using three digital workflows: 3D-printed denture teeth, CAD\u002FCAM-milled double cross-linked denture teeth, and prefabricated denture teeth. Occlusal wear will be assessed over 24 months using digital superimposition techniques. The study aims to determine whether 3D-printed denture teeth demonstrate superior wear resistance compared to CAD\u002FCAM-milled denture teeth.",[28,27],[27,87,88,89,90,91,92,93],"Complete dentures","Digital dentistry","3D printing","CAD\u002FCAM","Occlusal wear","Denture teeth","Randomized controlled trial","2026-05-08",{"date":96,"type":33},"2026-05-13",{"date":98,"type":21},"2026-09-01",{"date":100,"type":21},"2032-12-30",{"name":102,"class":40},"Najla Chebib"]