[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"effect-of-pericardial-closure-on-the-right-ventricular-function-post-cardiac-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:effect-of-pericardial-closure-on-the-right-ventricular-function-post-cardiac-surgery":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":4,"maxAge":4,"enrollmentInfo":16,"targetDuration":4,"studyType":19,"phases":20,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":5},"100657215","does-the-pericardial-closure-reduces-early-right-ventricular-dysfunction-after-cardiac-surgery-a-randomized-controlled-trial-100657215",false,"NCT07836426","Does the Pericardial Closure Reduces Early Right Ventricular Dysfunction After Cardiac Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients undergoing following surgeries\n\n  * aortic valve replacement (AVR).\n  * mitral valve replacement (MVR).\n  * combined coronary and\u002For valvular heart surgeries.\n  * coronary artery by-pass graft (CABG).\n\nExclusion Criteria:\n\n* • right ventricular dysfunction\n\n  * RV dilatation (RV diameter \\> 4.5)\n  * RV infarction\n  * pacemaker stimulation,\n  * severe left heart insufficiency (LV-EF ≤ 40%).\n  * tricuspid valve insufficiency \\> 2°.\n  * pulmonary valve insufficiency ≥2°,\n  * atrial fibrillation\u002Fflutter,\n  * pulmonary hypertension,\n  * state after pulmonary artery embolism.\n  * chronic obstructive pulmonary disease \\> GOLD 2, prior cardiac surgery.","ALL",{"count":17,"type":18},90,"ESTIMATED","INTERVENTIONAL",[21],"NA","The right ventricular (RV) function has a major influence on the outcomes of cardiac surgery\\[1,2\\]. Also affects the prognosis of patients undergoing heart surgery, where the development of right ventricular failure after surgery is linked to higher rates of morbidity and mortality\\[3\\]. Significant clinical consequences result from perioperative impairment of RV function, including increased need for inotropic support, prolonged intensive care unit admission, higher rates of hospital readmission, and a higher risk of in-hospital mortality.\\[2,4\\]. Regardless of the use of cardiopulmonary bypass, longitudinal evaluations of RV systolic function, such as tricuspid annular plane systolic excursion (TAPSE) and tricuspid annular systolic velocity (TASV\u002FS'), frequently decrease following elective coronary artery bypass grafting (CABG) \\[6,7\\]. Loss of pericardial restriction during pericardiotomy, ischemia from inadequate myocardial protection, and postoperative adhesions that modify RV shape and contraction patterns are theories explaining these perioperative alterations \\[4,8\\]. This study employed standard transthoracic echocardiography and speckle-tracking deformation analysis for the assessment of the effect of closing the pericardium on RV function post operatively versus leaving it open.",[24,25],"Effect of Pericardial Closure on the Right Ventricular Function Post Cardiac Surgery","Open Heart Surgery","NOT_YET_RECRUITING","2026-09-21",{"date":29,"type":30},"2026-09-23","ACTUAL",{"date":32,"type":18},"2026-12-10",{"date":34,"type":18},"2029-12",{"name":36,"class":37},"Assiut University","OTHER"]