[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"efficacy-validation-of-deep-microspicule-cream-for-anti-aging-and-whitening-on-mature-skin\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:efficacy-validation-of-deep-microspicule-cream-for-anti-aging-and-whitening-on-mature-skin":13},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":27,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100652405","efficacy-validation-of-deep-microspicule-cream-for-anti-aging-and-whitening-on-mature-skin-100652405",false,"NCT07774260","Efficacy Validation of Deep Microspicule Cream for Anti-aging and Whitening on Mature Skin","Inclusion Criteria:\n\n* Healthy male or female participants aged 40-65 years.\n* Presence of at least one facial aging or hyperpigmentation feature (e.g., eye area sagging, eye bags, crow's feet, fine lines, freckles, sun spots, uneven skin tone, or dullness).\n* Willing to complete 3 study visits within 4 weeks, comply with instrumental measurements, and maintain product logs.\n* Willing to sign the Informed Consent Form (ICF).\n\nExclusion Criteria:\n\n* Received facial aesthetic treatments (e.g., lasers, chemical peels, microneedling, energy-based therapies) within 4 weeks.\n* Used topical\u002Foral retinoic acid or strong whitening creams (e.g., high-concentration hydroquinone) within 4 weeks.\n* Severe sensitive skin, active atopic dermatitis, or obvious facial skin lesions\u002Finfections.\n* Facial salon or exfoliation treatments more frequent than once every 2 weeks.\n* Known allergy to seaweed-derived ingredients or product preservative systems.\n* Uncontrolled systemic diseases (e.g., diabetes, kidney\u002Fliver\u002Fcardiovascular diseases, severe infections, endocrine disorders, or cancer).\n* Pregnant, lactating, or planning to become pregnant.\n* Deemed unsuitable for participation by the investigator.",true,"ALL","40 Years","65 Years",{"count":20,"type":21},10,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study is a single-center, prospective, split-face self-controlled pilot trial designed to evaluate the anti-aging and whitening efficacy of the \"Deep Microspicule Cream\" (containing patented crystal microspicules encapsulating Penghu seaweed extract) on mature skin.",[13],[28],"Microspicule, Anti-aging, Whitening","NOT_YET_RECRUITING","2026-08-14",{"date":32,"type":33},"2026-08-19","ACTUAL",{"date":35,"type":21},"2026-09-01",{"date":37,"type":21},"2026-10-30",{"name":39,"class":40},"Chung Shan Medical University","OTHER"]