[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"elevated-cardiovascular-risk\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:elevated-cardiovascular-risk":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":4},"100653881","sacha-inchi-coq10-supplementation-and-cardiovascular-health-100653881",false,"NCT07792005","Sacha Inchi-CoQ10 Supplementation and Cardiovascular Health","Effects of Sacha Inchi-CoQ10 Supplementation on Endothelial-related Cardiovascular Function, Cardiometabolic Risk Factors, and Inflammatory Biomarkers Among Adults at Increased Cardiovascular Risk: A Double-blind Randomized Controlled Trial","Sacha-Q10","Inclusion Criteria:\n\n* Adults aged 40 to 75 years.\n* Male or female.\n* Have one or more cardiovascular risk factors or stable cardiovascular disease, including:\n\nHypertension; Dyslipidaemia; Controlled diabetes mellitus; or High cardiovascular risk, defined as Framingham Risk Score ≥10%.\n\n* Able to provide written informed consent.\n* Able and willing to comply with the study procedures and follow-up visits.\n\nExclusion Criteria:\n\n* Unstable cardiovascular disease.\n* Severe renal impairment.\n* Severe hepatic impairment.\n* Active malignancy.\n* Pregnant or lactating women.\n* Known allergy to any study components.\n* Current use of omega-3, Sacha Inchi oil or Coenzyme Q10 supplements within the past three months.\n* Participation in another clinical trial within the past three months.\n* Impaired decision-making capacity, including cognitive impairment or severe mental disorder.","ALL","40 Years","75 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to learn if Sacha Inchi-CoQ10 supplementation can improve cardiovascular health in adults who have an increased risk of cardiovascular disease. The study will also learn about the safety and tolerability of Sacha Inchi-CoQ10 supplementation.\n\nThe main questions it aims to answer are:\n\nDoes Sacha Inchi-CoQ10 supplementation improve cardiovascular function compared with placebo? Does Sacha Inchi-CoQ10 supplementation improve blood pressure, cholesterol, blood sugar, inflammation, and oxidative stress? Is Sacha Inchi-CoQ10 supplementation safe and well tolerated?\n\nResearchers will compare Sacha Inchi-CoQ10 supplementation with a placebo (a look-alike supplement that does not contain Sacha Inchi-CoQ10) to see whether the supplementation improves cardiovascular health.\n\nParticipants will:\n\nTake Sacha Inchi-CoQ10 supplementation or placebo for 12 weeks Visit the study clinic for screening, baseline, week 6, and week 12 assessments Have cardiovascular assessments, including echocardiography and blood pressure measurements Provide blood samples to assess cholesterol, blood sugar, inflammation, and oxidative stress Have their weight, body composition, and other health measurements assessed Complete questionnaires about their diet, physical activity, and quality of life Record their supplement intake and any symptoms or side effects during the study",[28,29,30],"Cardiovascular Disease (CVD)","Elevated Cardiovascular Risk","Endothelial Dysfunction",[32,33,34,35,36,37,38,39,40],"Sacha Inchi","Coenzyme Q10","Cardiovascular Disease","Endothelial Function","Oxidative Stress","Inflammation","Nutraceutical","Randomized Controlled Trial","Cardiovascular Risk","NOT_YET_RECRUITING","2026-08-27",{"date":44,"type":45},"2026-08-28","ACTUAL",{"date":47,"type":22},"2026-10",{"date":49,"type":22},"2027-12",{"name":51,"class":52},"Hospital Pengajar Universiti Putra Malaysia","OTHER"]