[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"emergency-department-patients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:emergency-department-patients":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,59,94],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":36,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":58},"100652838","single-lumen-midline-catheter-vs-ultrasound-guided-peripheral-iv-as-performed-by-bedside-emergency-department-registered-nurses-100652838",false,"NCT07779317","Single Lumen Midline Catheter vs Ultrasound Guided Peripheral IV as Performed by Bedside Emergency Department Registered Nurses","Superior Venous Access: Single Lumen Midline Catheter vs Ultrasound Guided Peripheral IV as Performed by Bedside Emergency Department Registered Nurses, A Randomized Clinical Trial","SUMMIT","Inclusion Criteria:\n\n* Adults 18 years of age or older\n* Presenting to the Albany Medical Center Emergency Department\n* Require intravenous access\n* Have difficult intravenous access (DIVA) defined by at least one of the following:\n* Two failed attempts at landmark-based or ultrasound-guided peripheral vascular access performed by qualified emergency department staff\n* A history of or active comorbid condition associated with difficult intravenous access, including:\n* Implanted vascular access port (current or previous)\n* End-stage renal disease with dialysis fistula\n* Sickle cell disease\n* Current or previous intravenous drug use\n* Self-reported difficult intravenous access plus one of the following:\n* A history of requiring two or more IV attempts during a previous healthcare encounter (self-reported or documented in the medical record)\n* A previous requirement for a rescue vascular access device after failed IV access, including:\n* Ultrasound-guided peripheral IV\n* Midline catheter\n* Peripherally inserted central catheter (PICC)\n* Central venous catheter (CVC)\n* Intraosseous catheter\n\nExclusion Criteria:\n\n* Younger than 18 years of age\n* Prisoners\n* Non-English-proficient patients\n* Patients in whom the device cannot be adequately stabilized because of tissue injury or treatment involving the available extremities (including burns, complex humeral fractures, or dialysis fistulas)\n* Patients who lack the capacity to provide informed consent and do not have an authorized legal representative available\n* Patients without an identifiable target vein on ultrasonography\n* Patients known to be pregnant\n* Previous enrollment in the study\n* Previous withdrawal from the study\n* Presentation during a period when no study proceduralists are available\n* Patients for whom the informed consent and enrollment process could delay time-sensitive medical care","ALL","18 Years",{"count":20,"type":21},292,"ESTIMATED","INTERVENTIONAL",[24],"NA","Obtaining intravenous (IV) access is one of the most common procedures performed in the emergency department (ED). IV access is necessary for many aspects of patient care, including blood tests, administration of medications and intravenous fluids, and diagnostic imaging. However, some patients have difficult intravenous access (DIVA), making it challenging to successfully place an IV catheter. Difficulty obtaining IV access can lead to delays in diagnosis and treatment, prolonged emergency department stays, multiple needle punctures, and increased patient discomfort.\n\nSeveral specialized IV devices are available for patients with DIVA. Two commonly used ultrasound-guided devices are long peripheral intravenous catheters and single-lumen midline catheters. Both devices are inserted into veins using ultrasound guidance, but they differ in catheter length and expected duration of use. Long peripheral IV catheters are commonly used in emergency departments but may fail relatively quickly. Midline catheters may remain functional for longer periods and may reduce the need for additional IV insertions during a patient's hospital stay. However, these devices have traditionally been inserted by specialized clinicians, such as members of vascular access teams, rather than by bedside emergency department nurses, who perform most vascular access procedures in many emergency departments.\n\nThe purpose of this study is to compare ultrasound-guided single-lumen midline catheters with ultrasound-guided long peripheral IV catheters when both procedures are performed by specially trained bedside emergency department nurses. The study will evaluate whether midline catheters can be inserted as successfully and as safely as long peripheral IV catheters in adult emergency department patients with difficult intravenous access.\n\nParticipants will be randomly assigned to receive either an ultrasound-guided single-lumen midline catheter or an ultrasound-guided long peripheral IV catheter. Researchers will compare the two devices by measuring procedural success, catheter-related complications, catheter dwell time, completion of care using the original device, and patient satisfaction.\n\nThe results of this study may help determine whether bedside emergency department nurses with training and experience in ultrasound-guided vascular access can successfully use single-lumen midline catheters in routine clinical practice. The study will also evaluate which vascular access device provides the best balance of safety, reliability, and patient experience for emergency department patients with difficult intravenous access. This information may help guide future recommendations for vascular access device selection in the emergency department.",[27,28,29,30,31,32,33,34,35],"Difficult Vein Access","Emergency Department Patients","Nurses Role","Midline Catheter","Ultrasound Assistance","Difficult Intravenous Access","Catheterization, Peripheral","Catheterization","Emergency Service, Hospital",[37,38,30,39,40,41,42,43,44,45],"DIVA","Ultrasound-Guided Vascular Access","Single-Lumen Midline Catheter","Long Peripheral Intravenous Catheter","Ultrasound-Guided Peripheral Intravenous Catheter","Emergency Department Nursing","Emergency Nursing","Vascular Access Device","Ultrasound-Guided Intravenous Access","RECRUITING","2026-08-18",{"date":49,"type":50},"2026-08-21","ACTUAL",{"date":52,"type":50},"2026-08-11",{"date":54,"type":21},"2027-03",{"name":56,"class":57},"Albany Medical College","OTHER",1,{"id":60,"slug":61,"hasResults":11,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":67,"targetDuration":4,"studyType":22,"phases":69,"briefSummary":70,"conditions":71,"keywords":75,"overallStatus":84,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":58},"100648876","er-vision-ai-study-100648876","NCT07727590","ER-VISION-AI Study","Multimodal Visual Language Model-Assisted Diagnostic Strategy in the Emergency Department: A Prospective Multicenter Randomized Controlled Trial (ER-VISION-AI Study)","ER-VISION-AI","Inclusion Criteria:\n\n* Age ≥18 years\n* Presentation to a participating emergency department with acute cardiopulmonary symptoms, including chest pain, dyspnea, palpitations, syncope, dizziness, or fever accompanied by cardiopulmonary symptoms\n* Performance of both a standard 12-lead electrocardiogram and chest radiography during the initial emergency department evaluation\n* Availability of initial clinical assessment, vital signs, laboratory findings, and all mandatory clinical information required for the multimodal AI workflow\n* Expected emergency department observation or hospital admission for at least 24 hours\n* Ability and willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Inability or refusal to provide written informed consent\n* Requirement for immediate life-saving intervention that precludes completion of the study workflow\n* Death before completion of the initial emergency department diagnostic assessment\n* Electrocardiographic quality insufficient for reliable physician or Artificial intelligence (AI) interpretation\n* Chest radiographic quality insufficient for reliable physician or Artificial intelligence (AI) interpretation\n* Cardiac pacing rhythm\n* Missing mandatory clinical information required for the multimodal Artificial intelligence (AI) workflow\n* Previous enrollment in the ER-VISION-AI trial\n* Inability to establish a blinded adjudicated reference diagnosis",{"count":68,"type":21},1000,[24],"Prospective, multicenter, randomized, open-label, blinded-endpoint (PROBE-like) clinical trial evaluating whether physician-supervised Generative Pre-trained Transformer (GPT)-assisted multimodal diagnostic support improves diagnostic concordance in emergency department patients presenting with acute cardiopulmonary symptoms.",[72,73,74,28],"Chest Pain","Dyspnea","Acute Cardiopulmonary Disease",[76,77,78,79,80,81,82,83],"Artificial intelligence","Large language model","Emergency department","Electrocardiography","Chest radiography","Multimodal AI","Clinical decision support","Randomized controlled trial","NOT_YET_RECRUITING","2026-07-21",{"date":87,"type":50},"2026-07-27",{"date":89,"type":21},"2027-01-01",{"date":91,"type":21},"2029-12-31",{"name":93,"class":57},"Ewha Womans University Mokdong Hospital",{"id":95,"slug":96,"hasResults":11,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":4,"eligibilityCriteria":100,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":101,"targetDuration":4,"studyType":103,"phases":4,"briefSummary":104,"conditions":105,"keywords":108,"overallStatus":84,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":58},"100642262","pulmonary-artery-pressure-in-predicting-pulmonary-embolism-in-patients-presenting-to-the-emergency-department-with-dyspnea-100642262","NCT07641400","Pulmonary Artery Pressure in Predicting Pulmonary Embolism in Patients Presenting To The Emergency Department With Dyspnea","The Diagnostic Value of The Difference Between Prior and Immediate Pulmonary Artery Pressure in Predicting Pulmonary Embolism in Patients Presenting To The Emergency Department With Dyspnea","Inclusion Criteria:\n\n* Presenting to the emergency department with dyspnea between the specified dates,\n* Being 18 years of age or older,\n* Being evaluated in the emergency department with a preliminary diagnosis of pulmonary embolism,\n* Having a recorded pulmonary artery pressure measurement at the time of hospital admission,\n* Having a previous pulmonary artery pressure measurement in the patient's records,\n* Having sufficient and complete clinical, laboratory, imaging, and echocardiography data available for the study.\n\nExclusion Criteria:\n\n* Patients under 18 years of age,\n* Lack of pulmonary artery pressure data from the time of emergency admission or from the previous period,\n* Lack of necessary clinical, laboratory, or imaging data for pulmonary embolism evaluation,\n* In cases of repeated admissions for the same patient, only the first suitable admission will be considered; other admissions will be excluded from the study,\n* Patients whose data is unavailable in the record system or whose data is insufficient to be analyzed for research purposes.Inclusion Criteria for the Study",{"count":102,"type":21},80,"OBSERVATIONAL","The aim of this study is to determine the usability of echocardiographic PAP changes obtained from emergency department records in the early risk stratification of pulmonary embolism.",[28,106,107],"Pulmonary Hypertension","Pulmonary Embolism",[109,110,111,112,113],"emergency deparment patients","pulmonary hypertension","pulmonary embolism","dispnea","chest pain","2026-06-06",{"date":116,"type":50},"2026-06-11",{"date":118,"type":21},"2026-06-01",{"date":120,"type":21},"2026-10-01",{"name":122,"class":57},"Antalya Health Sciences University"]