[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"end-stage-chronic-kidney-disease-treated-with-hemodialysis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:end-stage-chronic-kidney-disease-treated-with-hemodialysis":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100648862","randomized-trial-evaluating-the-effect-of-light-therapy-using-glasses-versus-a-sham-device-on-the-evolution-of-self-reported-depressive-disorders-in-chronic-hemodialysis-patients-100648862",false,"NCT07729358","Evaluation of the Effect of Light Therapy on the Evolution of Self-reported Depressive Disorders in Chronic Hemodialysis Patients","Randomized Trial Evaluating the Effect of Light Therapy Using Glasses Versus a Sham Device on the Evolution of Self-reported Depressive Disorders in Chronic Hemodialysis Patients","LUMIDIAL-2","Inclusion Criteria:\n\n* Patient informed about the nature, process, and objectives of the study and having signed a free and informed consent to participate,\n* Patient treated with conventional hemodialysis for at least 3 months and currently undergoing dialysis 3 times a week,\n* Patient covered by the french national social welfare\n\nNon-Inclusion Criteria:\n\n* Patient who has initiated or modified antidepressive treatment within the 4 weeks prior to the inclusion visit,\n* Patient with initiation of antidepressive treatment within the 10 weeks following the inclusion visit (screening and intervention periods),\n* Patient who has initiated or modified anxiolytic, hypnotic, or melatonin treatment within the 4 weeks prior to the inclusion visit,\n* Patient presenting with binocular blindness or age-related macular degeneration (AMD),\n* Patient receiving medical and\u002For surgical treatment for a retinal condition,\n* Patient who has undergone ocular surgery within the 12 weeks prior to the inclusion visit,\n* Patient scheduled for ocular surgery within the 10 weeks following the inclusion visit (screening and intervention periods),\n* Patient suffering from neurocognitive disorders, schizophrenia or other primary psychotic disorders, or bipolar disorder or related conditions,\n* Pregnant or breastfeeding patient,\n* Patient unable to understand the French language both orally and in writing, making self-assessment impossible,\n* Patient currently participating in another interventional research protocol, except for the IDE-3D protocol (RIPH2) conducted by the CH Annecy Genevois,\n* Patient who has already been randomized in the present study,\n* Patient under guardianship, curatorship, or placed under judicial protection.\n\nRandomisation criteria\n\nThe patient will be considered eligible for randomization if they have a HADS-D screening score dated within a maximum of 15 days and meet one of the following two criteria:\n\n* HADS-D screening score ≥ 8 and \\\u003C 15,\n* HADS-D screening score ≥ 15, provided that a medical follow-up assessment has been conducted following this diagnosis during the screening period, and that it does not lead to the recommendation for the initiation or modification of antidepressant treatment and\u002For psychotherapy within the 10 weeks following the inclusion visit (screening and intervention periods).","ALL","18 Years",{"count":20,"type":21},340,"ESTIMATED","INTERVENTIONAL",[24],"NA","Hemodialysis is an intensive treatment, with a lifestyle dictated by the organization of the dialysis center. This treatment is associated with a decrease in quality of life, an increase in sleep disorders, and depressive disorders.\n\nLight therapy could be a non-pharmacological option for treating depressive states in chronic hemodialysis patients. Indeed, the production of melatonin is stimulated by exposure to light of a defined intensity for 30 minutes in the morning. This hormone influences our sleep-wake cycle. In the general population, light therapy has demonstrated its benefits for depression. This practice could therefore improve sleep quality and mood in chronic hemodialysis patients who experience depressive symptoms.\n\nThe objective of this research is to evaluate the effect of light therapy on the reduction of depressive disorders experienced by chronic hemodialysis patients. Light therapy will be administered using glasses called \"Luminette®,\" three times a week for five weeks, on the days of dialysis sessions in the morning at the center or at home for patients undergoing afternoon dialysis",[27,28],"End-stage Chronic Kidney Disease Treated With Hemodialysis","Depressive Disorders",[30,31,32,33],"Mental health","Light Therapy","Therapeutic and Preventive Strategies","Patient Quality of Life","NOT_YET_RECRUITING","2026-08-13",{"date":37,"type":38},"2026-08-17","ACTUAL",{"date":40,"type":21},"2026-08-15",{"date":42,"type":21},"2028-12-15",{"name":44,"class":45},"Centre Hospitalier Annecy Genevois","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":59,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":5},"100641558","evaluation-of-depression-screening-methods-administered-by-registered-nurses-in-chronic-hemodialysis-patients-100641558","NCT07651436","Evaluation of Depression Screening Methods Administered by Registered Nurses in Chronic Hemodialysis Patients","IDE-3D","Inclusion Criteria:\n\n* Patient informed about the nature, process, and objectives of the study and having signed a free and informed consent to participate,\n* Patient treated with conventional hemodialysis for at least 3 months and currently undergoing dialysis 3 times a week,\n* Patient covered by the french national social welfare\n\nExclusion Criteria:\n\n* Patient suffering from dementia\n* Pregnant or breastfeeding patient\n* Patient unable to understand the French language both orally and in writing, - making self-assessment impossible\n* Patient currently participating in another interventional research protocol or in an exclusion period from such research\n* Patient who has already been included in this study\n* Patient under guardianship, curatorship, or placed under judicial protection.",{"count":55,"type":21},450,[24],"Hemodialysis is a vital replacement therapy for patients with end-stage chronic kidney disease, but it imposes a heavy, demanding, and prolonged management, associated with a significant deterioration in quality of life. Hemodialysis patients are exposed to numerous physical, organizational, and social constraints, including repeated and prolonged sessions at the center, dietary and fluid restrictions, chronic fatigue, and frequent comorbidities. Therefore, depressive disorders in hemodialysis patients represent a major public health issue.\n\nThe literature reports a high prevalence of depressive symptoms among hemodialysis patients, ranging from 22% to 60%, significantly higher than that observed in the general population. These disorders are associated with a significant deterioration in quality of life, increased hospitalizations, lower therapeutic adherence, an increased risk of suicide, and excess mortality. Despite these important clinical consequences, depressive disorders often remain underdiagnosed in hemodialysis.\n\nCurrent guidelines, including those from the Haute Autorité de Santé (HAS), emphasize the importance of regular quality of life assessments in patients with chronic kidney disease and recommend the use of validated questionnaires. However, they do not formalize a specific operational strategy for screening depressive disorders in routine hemodialysis practice, contributing to their under-evaluation.\n\nThe gold standard diagnosis of depressive disorders relies on a structured psychiatric interview, which is difficult to reconcile with the organizational constraints of dialysis centers. Standardized self-assessment tools, such as the Hospital Anxiety and Depression Scale (HADS), particularly its depression subscale (HADS-D), have been widely used. The HADS-D has the advantage of excluding somatic symptoms and has been validated in hemodialysis patients.\n\nHowever, self-assessment relies on the patient's ability to express their subjective experience. Thus, the self-administration of standardized questionnaires in these patients is often challenging due to their age, comorbidities, fatigue, and functional limitations, often necessitating the intervention of healthcare staff. In contrast, registered nurses (IDE) working in hemodialysis possess longitudinal clinical knowledge of patients, acquired over repeated sessions, which can serve as a relevant lever for rapid and standardized screening of depressive symptoms. To date, the diagnostic performance of structured nursing hetero-evaluation remains poorly documented.\n\nThe IDE-3D study aims to evaluate the ability of nurses to identify depressive symptoms in hemodialysis patients using structured tools, comparing the nursing hetero-evaluation of the HADS-D with the self-assessment conducted by the patient. It is part of a pragmatic approach aimed at improving the screening of depressive disorders in hemodialysis, structuring the care pathway, and enhancing the integration of mental health into the overall management of hemodialysis patients.",[28,27],[60,61,30],"Epidemiology","Diagnostic strategies","RECRUITING","2026-07-22",{"date":65,"type":38},"2026-07-23",{"date":67,"type":38},"2026-06-26",{"date":69,"type":21},"2028-10",{"name":44,"class":45}]